Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)RSQTNTA RIDGLR
Homology: Rat, human amino acid residues are identical.
ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAPB; DRT; EK6; ELK; ELK-related protein tyrosine kinase; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH tyrosine kinase 2; EPH-like kinase 6; EPHB3; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 1; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPHT3; ETK2; FLJ37986; HEK-6; HEK2; Hek5; MGC87492; NET; Neuronally-expressed EPH-related tyrosine kinase; PCBC; soluble EPHB1 variant 1; Tyro5; TYRO6; Tyrosine-protein kinase receptor EPH-2
Gene Aliases: 9330129L11; AW488255; C130099E04Rik; Cek6; ELK; Elkh; ENSMUSG00000074119; EPHB1; Ephb2; EPHT2; Epth2; Erk; HEK6; NET
Molecular Function: transmembrane signal receptor