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|Tested species reactivity||Virus|
|Published species reactivity||Virus|
|Host / Isotype||Mouse / IgG1, kappa|
|Clone||CS1, CS2, CS3, CS4|
|Immunogen||EBV-encoded recombinant latent membrane protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA5-12172 targets Epstein-Barr Virus in IHC (P) applications and shows reactivity with Bacteria samples.
The MA5-12172 immunogen is eBV-encoded recombinant latent membrane protein.
The Epstein-Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a cancer-causing virus of the herpes family, which includes herpes simplex virus 1 and 2, and is one of the most common viruses in humans. Epstein-Barr virus occurs worldwide and causes infectious mononucleosis (glandular fever). There is also strong evidence that the virus has a primary role in the pathogenesis of multiple autoimmune diseases, particularly dermatomyositis, systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Epstein-Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction.
MA5-12172 was used in immunohistochemistry to study the changes in germinal center after the Epstein-Barr virus infection
|Kurth J,Hansmann ML,Rajewsky K,Küppers R||Proceedings of the National Academy of Sciences of the United States of America (100:4730)||2003|