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Invitrogen
Epstein Barr Virus Monoclonal Antibody (1H1)
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Product Details
MA1-22677
Product Specifications
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H1
Immunogen
Hybridization of Sp2/0 myeloma cells with spleen cells of a Balb/c mice immunized with purified EBV
Conjugate
Form
Liquid
Amount
100 µg
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
Product Specific Information
MA1-22677 detects EBV in Virus samples.
MA1-22677 has been successfully used in Immunofluorescence procedures.
MA1-22677 immunogen corresponds to Hybridization of Sp2/0 myeloma cells with spleen cells of a Balb/c mice immunized with purified EBV.
Target Information
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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