Product References
Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer.
Breast cancer research and treatment
Jerjees DA,Alabdullah M,Green AR,Alshareeda A,Macmillan RD,Ellis IO,Rakha EA
MA5-13789 was used in immunohistochemistry to study the prognostic and clinical value of Ki67 proliferation index and HER2 expression in luminal breast cancer
Sun Jun 01 00:00:00 EDT 2014
Expression of the epidermal growth factor system in human middle ear cholesteatoma.
Acta oto-laryngologica
Thorup MB,Munk M,Poulsen SS,Gaihede M,Nexo E,Sorensen BS,Ovesen T
MA5-13789 was used in immunohistochemistry to study the expression of the EGFR system in patients with middle ear cholesteatoma
Sat Feb 01 00:00:00 EST 2014
CYT-1 isoform of ErbB4 is an independent prognostic factor in serous ovarian cancer and selectively promotes ovarian cancer cell growth in vitro.
Gynecologic oncology
Paatero I,Lassus H,Junttila TT,Kaskinen M,Bützow R,Elenius K
MA5-13789 was used in immunohistochemistry to study the role and prognostic value of ErbB4 CYT-1 isoform expression in serous ovarian cancer
Mon Apr 01 00:00:00 EDT 2013
Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.
Breast cancer research : BCR
Ko E,Park SE,Cho EY,Kim Y,Hwang JA,Lee YS,Nam SJ,Bang S,Park J,Kim DH
MA5-13789 was used in immunohistochemistry to study the clinicopathological significance of cystatin M loss in invasive breast cancer
Mon Sep 12 00:00:00 EDT 2011
Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.
Diagnostic pathology
Gulati S,Ytterhus B,Granli US,Gulati M,Lydersen S,Torp SH
MA5-13789 was used in immunohistochemistry to study the prognostic value of c-erbB2 expression in anaplastic astrocytomas
Tue Mar 23 00:00:00 EDT 2010
HER-family gene amplification and expression in resected pancreatic cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
te Velde EA,Franke AC,van Hillegersberg R,Elshof SM,de Weger RW,Borel Rinkes IH,van Diest PJ
MA5-13789 was used in immunohistochemistry to study the immunohistochemical expression of HER1-4 and gene amplification of HER2 in resected pancreatic cancer
Thu Oct 01 00:00:00 EDT 2009
Prognostic significance of oncogenic markers in ductal carcinoma in situ of the breast: a clinicopathologic study.
The breast journal
Altintas S,Lambein K,Huizing MT,Braems G,Asjoe FT,Hellemans H,Van Marck E,Weyler J,Praet M,Van den Broecke R,Vermorken JB,Tjalma WA
MA5-13789 was used in immunohistochemistry to evaluate oncogenic markers with prognostic significance in breast ductal carcinoma in situ
Wed Jul 08 00:00:00 EDT 2009
The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis.
Cancer research
Naresh A,Thor AD,Edgerton SM,Torkko KC,Kumar R,Jones FE
MA5-13789 was used in immunohistochemistry to study the role of HER4/4ICD and BH3-only protein in tamoxifen-induced apoptosis
Fri Aug 01 00:00:00 EDT 2008
Expression of tumor necrosis factor alpha converting enzyme in endocrine cancers.
American journal of clinical pathology
Kirkegaard T,Naresh A,Sabine VS,Tovey SM,Edwards J,Dunne B,Cooke TG,Jones FE,Bartlett JM
MA5-13789 was used in immunohistochemistry to study the immunohistochemical expression of TACE in endocrine cancers and its potential role in breast cancer apoptosis
Thu May 01 00:00:00 EDT 2008
Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.
Oncogene
Sundvall M,Peri L,Määttä JA,Tvorogov D,Paatero I,Savisalo M,Silvennoinen O,Yarden Y,Elenius K
MA5-13789 was used in immunocytochemistry to study the localization and function of alternative ErbB4 intracellular domains
Thu Oct 18 00:00:00 EDT 2007
Coexpression of c-erbB 1-4 receptor proteins in human glioblastomas. An immunohistochemical study.
Journal of experimental & clinical cancer research : CR
Torp SH,Gulati S,Johannessen E,Dalen A
MA5-13789 was used in immunohistochemistry to study the coexpression of c-erbB 1-4 receptor proteins in human glioblastomas
Sat Sep 01 00:00:00 EDT 2007
Phosphorylated HER-2 tyrosine kinase and Her-2/neu gene amplification as predictive factors of response to trastuzumab in patients with HER-2 overexpressing metastatic breast cancer (MBC).
European journal of cancer (Oxford, England : 1990)
Giuliani R,Durbecq V,Di Leo A,Paesmans M,Larsimont D,Leroy JY,Borms M,Vindevoghel A,Jerusalem G,D'Hondt V,Dirix L,Canon JL,Richard V,Cocquyt V,Majois F,Reginster M,Demol J,Kains JP,Delree P,Keppens C,Sotiriou C,Piccart MJ,Cardoso F
MA5-13789 was used in immunohistochemistry to identify prognostic indicators of response/resistance to trastuzumab in metastatic breast cancer
Thu Mar 01 00:00:00 EST 2007
Expression of the epidermal growth factor system in endometrioid endometrial cancer.
Gynecologic oncology
Ejskjaer K,Sørensen BS,Poulsen SS,Forman A,Nexø E,Mogensen O
MA5-13789 was used in immunohistochemistry to study the expression of the EGF system in endometrioid endometrial cancer
Mon Jan 01 00:00:00 EST 2007
Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1.
Molecular and cellular biology
Muraoka-Cook RS,Caskey LS,Sandahl MA,Hunter DM,Husted C,Strunk KE,Sartor CI,Rearick WA,McCall W,Sgagias MK,Cowan KH,Earp HS
MA5-13789 was used in Western Blotting to demonstrate that heregulin-induced HER4 activity inhibits cell proliferation and delays G(2)/M progression in breast cancer cells.
Fri Sep 01 00:00:00 EDT 2006
Essential erbB family phosphorylation in osteosarcoma as a target for CI-1033 inhibition.
Pediatric blood & cancer
Hughes DP,Thomas DG,Giordano TJ,McDonagh KT,Baker LH
MA5-13789 was used in immunohistochemistry to study the role of erbB family phosphorylation in osteosarcoma
Mon May 01 00:00:00 EDT 2006
Ovarian granulosa cell tumors frequently express EGFR (Her-1), Her-3, and Her-4: An immunohistochemical study.
Gynecologic oncology
Leibl S,Bodo K,Gogg-Kammerer M,Hrzenjak A,Petru E,Winter R,Denk H,Moinfar F
MA5-13789 was used in immunohistochemistry to study the immunohistochemical expression of EGFR family members in ovarian granulosa cell tumors
Sat Apr 01 00:00:00 EST 2006
Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation.
The Journal of pathology
Rakha EA,Putti TC,Abd El-Rehim DM,Paish C,Green AR,Powe DG,Lee AH,Robertson JF,Ellis IO
MA5-13789 was used in immunohistochemistry to study the morphological and immunophenotypic features of breast carcinomas with basal and myoepithelial differentiation
Wed Mar 01 00:00:00 EST 2006
Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas.
BMC cancer
Kountourakis P,Pavlakis K,Psyrri A,Rontogianni D,Xiros N,Patsouris E,Pectasides D,Economopoulos T
MA5-13789 was used in immunohistochemistry to study the prognostic value of HER3 and HER4 expression in colorectal adenocarcinomas
Tue Feb 28 00:00:00 EST 2006
The role of HER1-HER4 and EGFRvIII in hormone-refractory prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Edwards J,Traynor P,Munro AF,Pirret CF,Dunne B,Bartlett JM
MA5-13789 was used in immunohistochemistry to study the role of HER1-HER4 and EGFRvIII in hormone-refractory prostate cancer
Sun Jan 01 00:00:00 EST 2006
NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis.
Oncogene
Prentice LM,Shadeo A,Lestou VS,Miller MA,deLeeuw RJ,Makretsov N,Turbin D,Brown LA,Macpherson N,Yorida E,Cheang MC,Bentley J,Chia S,Nielsen TO,Gilks CB,Lam W,Huntsman DG
MA5-13789 was used in immunohistochemistry to investigate the association of NRG1 gene rearrangements with poor prognosis in breast cancer treatment
Thu Nov 10 00:00:00 EST 2005
Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix.
Gynecologic oncology
Lee CM,Shrieve DC,Zempolich KA,Lee RJ,Hammond E,Handrahan DL,Gaffney DK
MA5-13789 was used in immunohistochemistry to study the prognostic value of EGFR family member expression and phospo-Akt levels in cervical carcinoma treated with radiation therapy
Tue Nov 01 00:00:00 EST 2005
Expression of the epidermal growth factor system in human endometrium during the menstrual cycle.
Molecular human reproduction
Ejskjaer K,Sørensen BS,Poulsen SS,Mogensen O,Forman A,Nexø E
MA5-13789 was used in immunohistochemistry to study the importance of the EGF system in the growth of the human endometrium
Mon Aug 01 00:00:00 EDT 2005
Paclitaxel and carboplatin as first-line chemotherapy combined with gefitinib (IRESSA) in patients with advanced breast cancer: a phase I/II study conducted by the Hellenic Cooperative Oncology Group.
Breast cancer research and treatment
Fountzilas G,Pectasides D,Kalogera-Fountzila A,Skarlos D,Kalofonos HP,Papadimitriou C,Bafaloukos D,Lambropoulos S,Papadopoulos S,Kourea H,Markopoulos C,Linardou H,Mavroudis D,Briasoulis E,Pavlidis N,Razis E,Kosmidis P,Gogas H
MA5-13789 was used in immunohistochemistry to investigate the efficacy of the combination of paclitaxel, carboplatin and gefitinib against advanced breast cancer
Fri Jul 01 00:00:00 EDT 2005
Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival.
Cancer
Wiseman SM,Makretsov N,Nielsen TO,Gilks B,Yorida E,Cheang M,Turbin D,Gelmon K,Huntsman DG
MA5-13789 was used in immunohistochemistry to study the frequency and prognostic value of coexpression of HER-1, HER-2, HER-3, and HER-4 by breast carcinoma
Sun May 01 00:00:00 EDT 2005
H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Molecular cancer therapeutics
Carón RW,Yacoub A,Zhu X,Mitchell C,Han SI,Sasazuki T,Shirasawa S,Hagan MP,Grant S,Dent P
MA5-13789 was used in western blot to investigate the mechanism for radioresistance induced by H-RAS V12 in HCT116 cells
Tue Feb 01 00:00:00 EST 2005
Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma.
British journal of cancer
Abd El-Rehim DM,Pinder SE,Paish CE,Bell JA,Rampaul RS,Blamey RW,Robertson JF,Nicholson RI,Ellis IO
MA5-13789 was used in immunohistochemistry to study the expression of EGFR family members in invasive breast cancers
Mon Oct 18 00:00:00 EDT 2004
Exquisite antitumour response to trastuzumab in a patient with no evidence of Ras-Raf-MAPK and PI3K-Akt pathways activation.
Breast (Edinburgh, Scotland)
Mano MS,Awada A,Minisini A,Durbecq V,Di Leo A,Piccart M
MA5-13789 was used in immunohistochemistry to report on a case of a patient with HER2-overexpressing metastatic breast cancer highly sensitive to trastuzumab treatment
Sun Aug 01 00:00:00 EDT 2004
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes, chromosomes & cancer
Adélaïde J,Huang HE,Murati A,Alsop AE,Orsetti B,Mozziconacci MJ,Popovici C,Ginestier C,Letessier A,Basset C,Courtay-Cahen C,Jacquemier J,Theillet C,Birnbaum D,Edwards PA,Chaffanet M
MA5-13789 was used in immunohistochemistry to investigate a specific chromosomal aberration in breast and pancreatic cancer cell lines
Fri Aug 01 00:00:00 EDT 2003
CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling.
Genes & development
Yu WH,Woessner JF,McNeish JD,Stamenkovic I
MA5-13789 was used in immunohistochemistry and western blot to study the role of CD44 in forming a HSPG/MMP7/HB-EGF/ErbB4 complex and its role in regulating female reproductive organ remodelling
Fri Feb 01 00:00:00 EST 2002
Radiosensitization of malignant glioma cells through overexpression of dominant-negative epidermal growth factor receptor.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lammering G,Valerie K,Lin PS,Mikkelsen RB,Contessa JN,Feden JP,Farnsworth J,Dent P,Schmidt-Ullrich RK
MA5-13789 was used in western blot to study the role of a dominant-negative EGFR in the radiosensitization of malignant glioma cells
Thu Mar 01 00:00:00 EST 2001