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Evinacumab Antibody (MA5-42049) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human ANGPTL3 protein expressed in CHO cells using a Evinacumab biosimilar monoclonal antibody (Product # MA5-42049). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Product Details
MA5-42049
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human ANGPTL3
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
30mM histidine, pH 5.8, with 10% sucrose, 0.006% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911192
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Evinacumab is a biosimilar that targets ANGPTL3. This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: REGN 1500
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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