|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant protein corresponding to C-terminal cytoplasmic domain of human EAAT2|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12360 targets Excitatory Amino Acid Transporter 2 in IHC (P) applications and shows reactivity with Human samples.
The MA5-12360 immunogen is recombinant protein corresponding to C-terminal cytoplasmic domain of human EAAT2.
Human excitatory amino acid transportes regulating neurotransmitter concentrations at the excitatory glutamatertic synapses of the mammalian central nervous system. They reduce extracellular glutamate concentration modulating synaptic signaling which helps reduce the risk of excitotoxicity. Expression of EATT2 is restricted to motor cortex area of the brain. EATT1 blocks the transport mediated by EATT2. EATT2 shares homology to L-glutamate transporter (GLT-1) from brain tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.