|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Rabbit Polyclonal to F - box hCdc4 (69 kDa isoform) Protein|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23468 detects F-box hCdc4 in Human samples.
PA1-23468 has been successfully used in ELISA and Western Blot procedures.
PA1-23468 immunogen corresponds to Rabbit Polyclonal to F - box hCdc4 (69 kDa isoform) Protein.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of malignancies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.