Invitrogen

F4/80 Monoclonal Antibody (BM8), PE-eFluor™ 610, eBioscience™

Product Image Gallery

F4/80 Antibody in Flow Cytometry (Flow) — Staining of mouse resident peritoneal exudate cells with Anti-Mouse CD11b APC (Product # 17-0112-82) and 0.5 µg of Rat IgG2a K Isotype Control PE-eFluor® 610 (Product # 61-4321-82) (left) or 0.5 µg of Anti-Mouse F4/80 Antigen PE-eFluor® 610 (right). Cells in the large scatter population were used for analysis.

Product Details

61-4801-82

Applications	Tested Dilution	Publications
Immunohistochemistry (Frozen) (IHC (F))	-	View 1 publication 1 publication
Flow Cytometry (Flow)	1 µg/test	View 111 publications 111 publications
Miscellaneous PubMed (Misc)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Mouse
Published species	Hamster, Human, Mouse
Host/Isotype	Rat / IgG2a, kappa
Recommended Isotype Control	Rat IgG2a kappa Isotype Control (eBR2a), PE-eFluor™ 610, eBioscience™
Class	Monoclonal
Type	Antibody
Clone	BM8
Conjugate	PE-eFluor™ 610 Alexa Fluor 488 Alexa Fluor 532 Alexa Fluor 561 Alexa Fluor 660 Alexa Fluor 700 APC APC-eFluor 780 Biotin eFluor 450 eFluor 506 eFluor 570 eFluor 660 FITC Functional Grade PE PE-Cyanine5 PE-Cyanine7 PerCP-Cyanine5.5 Super Bright 436 Super Bright 600 Super Bright 645 Super Bright 702 Super Bright 780 Unconjugated
Excitation/Emission Profile	View spectra
Form	Liquid
Concentration	0.2 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.2
Contains	0.09% sodium azide
Storage conditions	4° C, store in dark, DO NOT FREEZE!
RRID	AB_2574612

Product Specific Information

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 160 kDa surface receptor. It belongs to the EGF-TM7 family of proteins. As such it contains seven EGF-like domains on its extracellular N-terminus, seven transmembrane spanning sequences, and an intracellular C-terminal domain showing homology to other TM7 superfamily members. The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as well. Expression of F4/80 commences during early myeloid development in vivo and can be upregulated on BM cells stimulated in vitro with M-CSF. Some populations of macrophages, especially in the lymphoid microenvironment, may be devoid of F4/80.

Applications Reported: This BM8 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This BM8 antibody has been tested by flow cytometric analysis of mouse resident peritoneal exudate cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

PE-eFluor® 610 can be excited with laser lines from 488-561 nm and emits at 607 nm. We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red®). Please make sure that your instrument is capable of detecting this fluorochome.

Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 488-561 nm; Emission: 607 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.

PloS one

Robinson EK,Covarrubias S,Zhou S,Carpenter S

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Sep 15 00:00:00 EDT 2021

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.

PloS one

Robinson EK,Covarrubias S,Zhou S,Carpenter S

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Sep 15 00:00:00 EDT 2021

Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH.

STAR protocols

Daemen S,Chan MM,Schilling JD

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jun 18 00:00:00 EDT 2021

Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.

Frontiers in immunology

Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR

61-4801 was used in Flow cytometry/Cell sorting to show dendritic cell PTPN2 might explain the central role for PTPN2 in the immune system to maintain immune tolerance.

Mon Apr 12 00:00:00 EDT 2021

Host deficiency in ephrin-A1 inhibits breast cancer metastasis.

F1000Research

Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness.

Frontiers in medicine

Hasan S,Johnson MC,Kini AR,Baldea AJ,Muthumalaiappan K

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Nov 03 00:00:00 EST 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Zhao SJ,Liu H,Chen J,Qian DF,Kong FQ,Jie J,Yin GY,Li QQ,Fan J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.

Cell death discovery

Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.

Immunity

Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W

61-4801 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying itching associated with cutaneous wound healing, focusing on the contribution of soluble factors released during healing.

Tue Aug 18 00:00:00 EDT 2020

Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.

Frontiers in immunology

Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Aug 17 00:00:00 EDT 2020

Pulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.

ACS nano

Perry JL,Tian S,Sengottuvel N,Harrison EB,Gorentla BK,Kapadia CH,Cheng N,Luft JC,Ting JP,DeSimone JM,Pecot CV

61-4801 was used in Flow cytometry/Cell sorting to utilize PRINT (particle replication in nonwetting templates) nanoparticles as a vehicle to deliver CpG into murine lungs through orotracheal instillations.

Tue Jun 23 00:00:00 EDT 2020

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer.

Journal of hematology & oncology

Lu CS,Shiau AL,Su BH,Hsu TS,Wang CT,Su YC,Tsai MS,Feng YH,Tseng YL,Yen YT,Wu CL,Shieh GS

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2020

Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells.

Oncogene

Cheng R,Billet S,Liu C,Haldar S,Choudhury D,Tripathi M,Hav M,Merchant A,Hu T,Huang H,Zhou H,Bhowmick NA

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

CTNNB1/β-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes.

Science advances

Chen M,Lu P,Ma Q,Cao Y,Chen N,Li W,Zhao S,Chen B,Shi J,Sun Y,Shen H,Sun L,Shen J,Liao Q,Zhang Y,Hong J,Gu W,Liu R,Ning G,Wang W,Wang J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

p40 -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection.

Frontiers in immunology

Li Y,Lv M,Su C,Long S,Zhang W,Conway KL,Li W,Xavier RJ,Shi HN

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.

Frontiers in immunology

Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.

Cellular & molecular immunology

Du X,Wu Z,Xu Y,Liu Y,Liu W,Wang T,Li C,Zhang C,Yi F,Gao L,Liang X,Ma C

61-4801 was used in Flow cytometry/Cell sorting to analyze Tim-3 expression on different subpopulations of liver macrophages and further investigate the potential roles of Tim-3 on hepatic macrophages in methionine and choline-deficient diet (MCD)-induced NASH mice.

Fri Nov 01 00:00:00 EDT 2019

Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.

Nature communications

Kusano T,Ehirchiou D,Matsumura T,Chobaz V,Nasi S,Castelblanco M,So A,Lavanchy C,Acha-Orbea H,Nishino T,Okamoto K,Busso N

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2019

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.

PLoS genetics

Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila.

Cell reports

Zhang R,Earnest JT,Kim AS,Winkler ES,Desai P,Adams LJ,Hu G,Bullock C,Gold B,Cherry S,Diamond MS

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Sep 03 00:00:00 EDT 2019

TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding.

Journal of translational medicine

Liu C,Li P,Li H,Wang S,Ding L,Wang H,Ye H,Jin Y,Hou J,Fang X,Shu Q

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Sep 02 00:00:00 EDT 2019

Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis.

Purinergic signalling

Rothweiler S,Feldbrügge L,Jiang ZG,Csizmadia E,Longhi MS,Vaid K,Enjyoji K,Popov YV,Robson SC

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun Sep 01 00:00:00 EDT 2019

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Nature

Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.

Molecular metabolism

Yang H,Xie T,Li D,Du X,Wang T,Li C,Song X,Xu L,Yi F,Liang X,Gao L,Yang X,Ma C

61-4801 was used in Flow cytometry/Cell sorting to study T cell immunoglobulin domain and mucin domain-3 as a regulator in renal inflammation.

Wed May 01 00:00:00 EDT 2019

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.

Nature communications

Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Feb 22 00:00:00 EST 2019

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Scientific reports

Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jan 30 00:00:00 EST 2019

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.

Scientific reports

Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Nov 02 00:00:00 EDT 2018

Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.

The Journal of biological chemistry

Spurthi KM,Sarikhani M,Mishra S,Desingu PA,Yadav S,Rao S,Maity S,Tamta AK,Kumar S,Majumdar S,Jain A,Raghuraman A,Khan D,Singh I,Samuel RJ,Ramachandra SG,Nandi D,Sundaresan NR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Aug 24 00:00:00 EDT 2018

Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression.

The Journal of biological chemistry

Hamlin AN,Chinnarasu S,Ding Y,Xian X,Herz J,Jaeschke A,Hui DY

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jun 22 00:00:00 EDT 2018

Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

American journal of physiology. Gastrointestinal and liver physiology

Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Insulin resistance causes inflammation in adipose tissue.

The Journal of clinical investigation

Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Apr 02 00:00:00 EDT 2018

Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells.

International journal of molecular sciences

Lee CR,Lee W,Cho SK,Park SG

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Mar 15 00:00:00 EDT 2018

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.

JCI insight

Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Feb 08 00:00:00 EST 2018

Characterization of Stress and Innate Immunity Resistance of Wild-Type and Δp66 Borrelia burgdorferi.

Infection and immunity

Curtis MW,Hahn BL,Zhang K,Li C,Robinson RT,Coburn J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.

International journal of obesity (2005)

Chang CJ,Lu CC,Lin CS,Martel J,Ko YF,Ojcius DM,Wu TR,Tsai YH,Yeh TS,Lu JJ,Lai HC,Young JD

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.

Stem cell research & therapy

Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Nov 10 00:00:00 EST 2017

BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.

Scientific reports

Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Nov 08 00:00:00 EST 2017

Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.

Journal of immunology (Baltimore, Md. : 1950)

Li Z,Jiao Y,Fan EK,Scott MJ,Li Y,Li S,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Zoledronic acid inhibits infiltration of tumor-associated macrophages and angiogenesis following transcatheter arterial chemoembolization in rat hepatocellular carcinoma models.

Oncology letters

Zhou DY,Qin J,Huang J,Wang F,Xu GP,Lv YT,Zhang JB,Shen LM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis.

Scientific reports

Komine S,Akiyama K,Warabi E,Oh S,Kuga K,Ishige K,Togashi S,Yanagawa T,Shoda J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Sep 20 00:00:00 EDT 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

Evaluation of trained immunity by β-1, 3 (d)-glucan on murine monocytes in vitro and duration of response in vivo.

Immunology and cell biology

Garcia-Valtanen P,Guzman-Genuino RM,Williams DL,Hayball JD,Diener KR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.

Scientific reports

Shintani Y,Ito T,Fields L,Shiraishi M,Ichihara Y,Sato N,Podaru M,Kainuma S,Tanaka H,Suzuki K

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Jul 31 00:00:00 EDT 2017

Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy.

Cell stem cell

Lechner AJ,Driver IH,Lee J,Conroy CM,Nagle A,Locksley RM,Rock JR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Jul 06 00:00:00 EDT 2017

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.

Cell death & disease

Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu May 04 00:00:00 EDT 2017

TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.

eLife

Ku AT,Shaver TM,Rao AS,Howard JM,Rodriguez CN,Miao Q,Garcia G,Le D,Yang D,Borowiak M,Cohen DN,Chitsazzadeh V,Diwan AH,Tsai KY,Nguyen H

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed May 03 00:00:00 EDT 2017

RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

EMBO molecular medicine

Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Particle and fibre toxicology

Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Apr 14 00:00:00 EDT 2017

IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.

Cell reports

Spadaro O,Camell CD,Bosurgi L,Nguyen KY,Youm YH,Rothlin CV,Dixit VD

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Apr 11 00:00:00 EDT 2017

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.

The Journal of clinical investigation

Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Microarray analysis of circular RNA expression patterns in polarized macrophages.

International journal of molecular medicine

Zhang Y,Zhang Y,Li X,Zhang M,Lv K

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner.

Immunity, inflammation and disease

Owusu-Boaitey N,Bauckman KA,Zhang T,Mysorekar IU

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Nov 11 00:00:00 EST 2016

Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling.

Scientific reports

Cousins FL,Kirkwood PM,Saunders PT,Gibson DA

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Nov 09 00:00:00 EST 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

NADPH Oxidases Are Essential for Macrophage Differentiation.

The Journal of biological chemistry

Xu Q,Choksi S,Qu J,Jang J,Choe M,Banfi B,Engelhardt JF,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Sep 16 00:00:00 EDT 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression.

Hypertension (Dallas, Tex. : 1979)

Wang H,Hou L,Kwak D,Fassett J,Xu X,Chen A,Chen W,Blazar BR,Xu Y,Hall JL,Ge JB,Bache RJ,Chen Y

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice.

Scientific reports

Dou GR,Li N,Chang TF,Zhang P,Gao X,Yan XC,Liang L,Han H,Wang YS

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jun 24 00:00:00 EDT 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.

Oncogene

Das S,Rachagani S,Sheinin Y,Smith LM,Gurumurthy CB,Roy HK,Batra SK

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu May 19 00:00:00 EDT 2016

Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity.

JCI insight

Sassmann-Schweda A,Singh P,Tang C,Wietelmann A,Wettschureck N,Offermanns S

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu May 19 00:00:00 EDT 2016

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.

Immunity

Tian Y,Kuo CF,Akbari O,Ou JH

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue May 17 00:00:00 EDT 2016

Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.

Journal of lipid research

Chattopadhyay A,Navab M,Hough G,Grijalva V,Mukherjee P,Fogelman HR,Hwang LH,Faull KF,Lusis AJ,Reddy ST,Fogelman AM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Targeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma.

Oncoimmunology

Bu LL,Yu GT,Deng WW,Mao L,Liu JF,Ma SR,Fan TF,Hall B,Kulkarni AB,Zhang WF,Sun ZJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

PloS one

Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Apr 28 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway.

BioMed research international

Jin X,Yao T,Zhou Z,Zhu J,Zhang S,Hu W,Shen C

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Mar 18 00:00:00 EDT 2016

Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.

Cancer discovery

Lee KE,Spata M,Bayne LJ,Buza EL,Durham AC,Allman D,Vonderheide RH,Simon MC

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2016

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.

Proceedings of the National Academy of Sciences of the United States of America

Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Dec 29 00:00:00 EST 2015

Niacin reverses migratory macrophage foam cell arrest mediated by oxLDL in vitro.

PloS one

Huang H,Koelle P,Fendler M,Schroettle A,Czihal M,Hoffmann U,Kuhlencordt PJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Dec 17 00:00:00 EST 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.

International journal of obesity (2005)

Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun Nov 01 00:00:00 EDT 2015

LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.

eLife

Freedman TS,Tan YX,Skrzypczynska KM,Manz BN,Sjaastad FV,Goodridge HS,Lowell CA,Weiss A

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Oct 30 00:00:00 EDT 2015

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

Endocrinology

Schoiswohl G,Stefanovic-Racic M,Menke MN,Wills RC,Surlow BA,Basantani MK,Sitnick MT,Cai L,Yazbeck CF,Stolz DB,Pulinilkunnil T,O'Doherty RM,Kershaw EE

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2015

A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.

Disease models & mechanisms

Williams BB,Tebbutt NC,Buchert M,Putoczki TL,Doggett K,Bao S,Johnstone CN,Masson F,Hollande F,Burgess AW,Scott AM,Ernst M,Heath JK

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sat Aug 01 00:00:00 EDT 2015

Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.

Frontiers in immunology

Vogel AJ,Brown DM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Jul 10 00:00:00 EDT 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.

Nature communications

Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jun 24 00:00:00 EDT 2015

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Systemically delivered adipose stromal vascular fraction cells disseminate to peripheral artery walls and reduce vasomotor tone through a CD11b+ cell-dependent mechanism.

Stem cells translational medicine

Morris ME,Beare JE,Reed RM,Dale JR,LeBlanc AJ,Kaufman CL,Zheng H,Ng CK,Williams SK,Hoying JB

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

PloS one

Karpurapu M,Ranjan R,Deng J,Chung S,Lee YG,Xiao L,Nirujogi TS,Jacobson JR,Park GY,Christman JW

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Jan 20 00:00:00 EST 2015

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity.

Cell metabolism

Hernandez ED,Lee SJ,Kim JY,Duran A,Linares JF,Yajima T,Müller TD,Tschöp MH,Smith SR,Diaz-Meco MT,Moscat J

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Miscellaneous

Tue Sep 02 00:00:00 EDT 2014

The plexin C1 receptor promotes acute inflammation.

European journal of immunology

König K,Marth L,Roissant J,Granja T,Jennewein C,Devanathan V,Schneider M,Köhler D,Zarbock A,Rosenberger P

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Sep 01 00:00:00 EDT 2014

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Development (Cambridge, England)

Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

Dietary oleic acid increases m2 macrophages in the mesenteric adipose tissue.

PloS one

Camell C,Smith CW

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon May 12 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

A role for the ITAM signaling module in specifying cytokine-receptor functions.

Nature immunology

Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Apr 01 00:00:00 EDT 2014

Structure-based programming of lymph-node targeting in molecular vaccines.

Nature

Liu H,Moynihan KD,Zheng Y,Szeto GL,Li AV,Huang B,Van Egeren DS,Park C,Irvine DJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Mar 27 00:00:00 EDT 2014

The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury.

PloS one

König K,Köhler D,Granja T,Jennewein C,Tran N,Mirakaj V,Kröhnert F,Rosenberger P

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Apr 02 00:00:00 EDT 2013

Modular 'click-in-emulsion' bone-targeted nanogels.

Advanced materials (Deerfield Beach, Fla.)

Heller DA,Levi Y,Pelet JM,Doloff JC,Wallas J,Pratt GW,Jiang S,Sahay G,Schroeder A,Schroeder JE,Chyan Y,Zurenko C,Querbes W,Manzano M,Kohane DS,Langer R,Anderson DG

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Wed Mar 13 00:00:00 EDT 2013

PI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.

PloS one

Comerford I,Litchfield W,Kara E,McColl SR

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Feb 26 00:00:00 EST 2013

Dose-dense chemotherapy improves mechanisms of antitumor immune response.

Cancer research

Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2013

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Blood

He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Oct 11 00:00:00 EDT 2012

Suppression and regression of choroidal neovascularization in mice by a novel CCR2 antagonist, INCB3344.

PloS one

Xie P,Kamei M,Suzuki M,Matsumura N,Nishida K,Sakimoto S,Sakaguchi H,Nishida K

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Mon Apr 23 00:00:00 EDT 2012

Induction of autophagy is essential for monocyte-macrophage differentiation.

Blood

Zhang Y,Morgan MJ,Chen K,Choksi S,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Mar 22 00:00:00 EDT 2012

Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain.

Journal of neuroinflammation

Howe CL,Lafrance-Corey RG,Sundsbak RS,Lafrance SJ

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Mar 09 00:00:00 EST 2012

p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.

Blood

Cudejko C,Wouters K,Fuentes L,Hannou SA,Paquet C,Bantubungi K,Bouchaert E,Vanhoutte J,Fleury S,Remy P,Tailleux A,Chinetti-Gbaguidi G,Dombrowicz D,Staels B,Paumelle R

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2011

Myeloid cells migrate in response to IL-24.

Cytokine

Buzas K,Oppenheim JJ,Zack Howard OM

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2011

Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.

The American journal of pathology

Yang L,Cui H,Wang Z,Zhang B,Ding J,Liu L,Ding HF

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Tue Jun 01 00:00:00 EDT 2010

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.

Nature immunology

Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M

Published figure using F4/80 monoclonal antibody (Product # 61-4801-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2008

Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro.

Journal of leukocyte biology

Geutskens SB,Otonkoski T,Pulkkinen MA,Drexhage HA,Leenen PJ

Sat Oct 01 00:00:00 EDT 2005

Bioinformatics

Protein Aliases: Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; lymphocyte antigen 71

Gene Aliases: Adgre1; DD7A5-7; EGF-TM7; Emr1; F4/80; Gpf480; Ly71; TM7LN3

UniProt ID: (Mouse) Q61549

Entrez Gene ID: (Mouse) 13733

Molecular Function: G-protein coupled receptor