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|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||mouse F4/80 which is a macrophage-restricted cell surface glycoprotein.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 2 publications below|
EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. EMR1 has been reported to be expressed in human peripheral blood mononuclear cells, monocytes, and hematopoietic and solid tumor-derived cell lines. ESTs have been isolated from human normal spleen and mixed liver/spleen libraries and from human kidney, colon, brain, and bone marrow cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cell based metabolic barriers to glucose diffusion: macrophages and continuous glucose monitoring.
A14800 was used in immunohistochemistry - paraffin section to assess the role of MQ at the glucose-sensor tissue interface
|Klueh U,Frailey JT,Qiao Y,Antar O,Kreutzer DL||Biomaterials (35:3145)||2014|
Impact of macrophage deficiency and depletion on continuous glucose monitoring in vivo.
A14800 was used in immunohistochemistry - paraffin section to assess the role of macrophages on continuous glucose monitoring
|Klueh U,Qiao Y,Frailey JT,Kreutzer DL||Biomaterials (35:1789)||2014|
DD7A5-7, F4/80, Emr1, Ly71, TM7LN3, Gpf480, EGF-TM7
EGF-like module containing, mucin-like, hormone receptor-like sequence 1, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, cell surface glycoprotein F4/80, lymphocyte antigen 71, EMR1, F4/80, TM7LN3