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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment, corresponding to amino acids 853-1052 of Human FAK.|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-21799 detects FAK in Human, Mouse, and Rat samples.
PA1-21799 has been successfully used in Immunofluorescence and Western Blot procedures.
PA1-21799 immunogen corresponds to amino acids 853-1052 of Human FAK.
FAK (Focal Adhesion Associated Protein-Tyrosine Kinase) is a widely expressed non receptor protein tyrosine kinase (PTK). FAK has a central catalytic domain and a C terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors. Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FADK; FADK 1; FAK-related non-kinase polypeptide; Focal Adhesion Kinase; focal adhesion kinase 1; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase-related nonkinase; focal ashension kinase 1; pp125FAK; protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; Protein Tyrosine Kinase 2; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2
FADK; FAK; FAK1; FRNK; Kiaa4203; mKIAA4203; p125FAK; pp125FAK; PPP1R71; PTK2