|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1:500-1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Human FANCD2 fusion protein|
|Storage buffer||PBS, pH 7.2|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-23333 detects FANCD2 in Human samples.
MA1-23333 has been successfully used in ELISA and Western Blot procedures.
MA1-23333 immunogen corresponds to Human FANCD2 fusion protein.
Fanconi Anemia Complementation Group D2 (FANCD2) protein is one of at least six factors shown to be involved in the autosomal-recessive cancer-prone disorder, Fanconi Anemia (FA). FA group D has been shown to be comprised of two separate proteins, FANCD1 and FANCD2. Mutations in BRCA2 can cause FANCD1. FANCD2 has been shown to colocalize with BRCA1 in ionizing radiation-induced foci. FANCD2 is involved in genomic resistance to DNA cross-linking reagents, and the arrest of DNA synthesis following exposure to ionizing radiation. FANCD2 has been shown to directly interact with NBS1
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp762A223; FA-D2; FA4; FACD; FAD; FAD2; FANCD; Fanconi anemia group D2 protein; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Gene Aliases: FA-D2; FA4; FACD; FAD; FAD2; FANCD; FANCD2
UniProt ID: (Human) Q9BXW9
Entrez Gene ID: (Human) 2177
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