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|Tested species reactivity||Dog, Cat, Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||synthetic peptide RGQSCNNQPLNHKVYMRNSKYPEDL, corresponding to amino acids 196-220 of Mouse Fas Ligand.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 µg/50 µl blood or 5x10^5 cells|
|Immunocytochemistry (ICC)||20 µg/ml|
|Immunofluorescence (IF)||20 µg/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 2 publications below|
MA1-34171 detects FAS from mouse, human, feline, canine samples.
MA1-34171 has been successfully used in immunocytochemistry, Western blot applications.
The MA1-34171 immunogen is: Synthetic peptide: RGQSCNNQPLNHKVYMRNSKYPEDL, corresponding to amino acids 196-220 of Mouse Fas Ligand.
Many cells can be activated to undergo apoptosis following the interaction of selected ligands with cell surface receptors. One of the most studied receptors include the Fas receptor. Apoptosis mediated by both signaling cascades results in activation of
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma.
MA1-34171 was used in western blot to study the role of cortactin overexpression in increasing invasion potential in oral squamous cell carcinoma
|Yamada S,Yanamoto S,Kawasaki G,Mizuno A,Nemoto TK||Pathology oncology research : POR (16:523)||2010|
Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells.
MA1-34171 was used in western blot to study the biological functions of the epidermal growth factor receptor and DNA-dependent protein kinase interaction
|Bandyopadhyay D,Mandal M,Adam L,Mendelsohn J,Kumar R||The Journal of biological chemistry (273:1568)||1998|
ALPS1A; APO-1; apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; CD95; CD95 antigen; Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; FAS1; FASLG receptor; FASTM; lymphoproliferation; TNF receptor superfamily member 6; TNFRSF6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily, member 6
AI196731; ALPS1A; APO-1; APO1; APT1; CD95; FAS; FAS1; FASTM; lpr; TNFR6; TNFRSF6