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NeoBiotechnologies
FAT1 (FAT atypical cadherin 1) Monoclonal Antibody (FAT1-3D7/1)
Product Details
2195-MSM1-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
FAT1-3D7/1
Immunogen
Cytoplasmic domain of Drosophila Fat protein.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein L
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
Target Information
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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