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This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.
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Protein Aliases: BJ-HCC-2 antigen; Cancer/testis antigen 43; CT43; fetal and adult testis expressed transcript protein; Fetal and adult testis-expressed transcript protein; Tumor antigen BJ-HCC-2
Gene Aliases: CT43; FATE; FATE1
UniProt ID: (Human) Q969F0
Entrez Gene ID: (Human) 89885
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