|Immunohistochemistry (Paraffin) (IHC (P))||5-10 ug/ml|
|Western Blot (WB)||0.3-1.0 ug/ml|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (VFSNNDEGLINKK) corresponding to the N-terminus amino acids of FBXL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and rat based on sequence homology.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs , which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZP564P0622; F-box and leucine-rich repeat protein 2; F-box protein containing leucine-rich repeats; F-box protein FBL2/FBL3; F-box/LRR-repeat protein 2; FBL2; FBL3; FBXL2
Gene Aliases: FBL2; FBL3; FBXL2; RGD1562243
UniProt ID: (Human) Q9UKC9
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