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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant soluble CD89.|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||10 µg/ml|
|Inhibition Assays (IA)||4 µg per 4x10^5 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Blocking Assay (BLOCK)||See 1 publications below|
This antibody recognizes the EC1 domain of the FcaRI extracellular region.
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FcαRI-mediated inhibition of IL-12 production and priming by IFN-γ of human monocytes and dendritic cells.
MA1-72500 was used in blocking or activating experiment to study the mechanism by which FcalphaRI on monocytes and dendritic cells inhibits IL-12 production and type 1 activation
|Lecocq M,Detry B,Guisset A,Pilette C||Journal of immunology (Baltimore, Md. : 1950) (190:2362)||2013|
CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; immunoglobulin alpha Fc receptor
CD89; CTB-61M7.2; FcalphaRI; FCAR