Immunogen sequence: LTFLLFSCPH RLREHLERGR GNLEWKEPPS MRLKARPSSP GFSVLTCSAF SFYPPELQLR FLRNGLAAGT GQGDFGPNSD GSFHASSSLT VKSGDEHHYC CIVQHAGLAQ PLRVELESPA KS
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.
Binds to an epitope located within the peptide sequence RLREHLERGRGNLEW as determined by overlapping synthetic peptides.
FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fc fragment of IgG, receptor, transporter, alpha; FcRn; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; transmembrane alpha chain of the neonatal receptor
Gene Aliases: alpha-chain; FCGRT; FCRN
UniProt ID: (Human) P55899
Entrez Gene ID: (Human) 2217