This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
MA5-15357 targets FER in IF, IHC, and WB applications and shows reactivity with Human and mouse samples.
The MA5-15357 immunogen is purified recombinant fragment of human FER expressed in E. Coli.
MA5-15357 detects FER which has a predicted molecular weight of approximately 95kDa.
Protein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells. FER is found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes. The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines. Data suggest a biological role for Fer in regulation of leukocyte recruitment during the innate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-FER; EC 188.8.131.52; Feline encephalitis virus-related kinase FER; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p94-FER; phosphoprotein NCP94; protein phosphatase 1, regulatory subunit 74; Proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase FER; Tyrosine kinase 3; tyrosine protein kinase FLK; Tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
Gene Aliases: AV082135; C330004K01Rik; FER; Fert; Fert2; Flk; Flk_retired; p94-Fer; PPP1R74; TYK3