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Product Details
TA811441
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2C2
Immunogen
Full length human recombinant protein of human FHIT produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenosine 5'-monophosphoramidase FHIT; Adenylylsulfatase; Adenylylsulfate-ammonia adenylyltransferase; AP3A hydrolase; AP3Aase; Bis(5'-adenosyl)-triphosphatase; bis5'-adenosyl-triphosphatase; Diadenosine 5',5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
Gene Aliases: AP3Aase; FHIT; FRA3B
UniProt ID: (Human) P49789, (Rat) Q9JIX3
Entrez Gene ID: (Human) 2272, (Rat) 60398
purine nucleotide metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
nucleotide metabolic process
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
intrinsic apoptotic signaling pathway by p53 class mediator
DNA replication
diadenosine triphosphate catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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