Sequence of this protein is as follows: DGHHCCLKCF DKFCANTCVE CRKPIGADSK EVHYKNRFWH DTCFRCAKCL HPLANETFVA KDNKILCNKC TTREDSPKCK GCFKAIVAGD QNVEYKGT
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
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Protein Aliases: bA535K18.1; FHL-1; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYO-T; KyoT; LIM protein SLIMMER; MGC111107; RAM14-1; RBP-associated molecule 14-1; RP11-535K18.1; Skeletal muscle LIM-protein 1; SLIM
Gene Aliases: FHL-1; FHL1; FHL1A; FHL1B; FLH1A; KYOT; RAM14-1; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA