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Product Details
MA5-35702
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
ARC1259 |
Immunogen |
A synthetic peptide corresponding to amino acids 1-100 of human FKBP8. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.4 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2849602 |
Target Information
FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, it does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 38 kDa FK506-binding protein; 38 kDa FKBP; FK506 binding protein 8, 38kDa; FK506-binding protein 38; FK506-binding protein 8; FK506-binding protein 8 (38kD); FKBP-38; FKBP-8; FKBPR38; hFKBP38; mFKBP38; Peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; Rotamase
Gene Aliases: 38kDa; FKBP-38; FKBP-8; FKBP38; FKBP8; FKBPr38; Sam11
UniProt ID: (Human) Q14318, (Rat) Q3B7U9, (Mouse) O35465
Entrez Gene ID: (Human) 23770, (Rat) 290652, (Mouse) 14232
Molecular Function:
chaperone
protein peptidyl-prolyl isomerization
cell fate specification
apoptotic process
smoothened signaling pathway
viral process
dorsal/ventral neural tube patterning
positive regulation of BMP signaling pathway
multicellular organism growth
intracellular signal transduction
camera-type eye development
negative regulation of apoptotic process
chaperone-mediated protein folding
dorsal/ventral pattern formation
regulation of gene expression
neural tube development
regulation of BMP signaling pathway
protein folding
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