|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15550 targets FLT1 in WB applications and shows reactivity with Human samples.
The MA5-15550 immunogen is purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
MA5-15550 detects FLT1 which has a predicted molecular weight of approximately 100kDa.
This gene encodes a member of the vascular endothelial growth factor receptor family. VEGFR family members are receptor tyrosine kinases which contain an extracellular ligand-binding region with seven immunoglobulin domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.