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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:5,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:300 | - |
Immunocytochemistry (ICC/IF) |
1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Pig |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
3F1F7 |
Immunogen |
FMO2 Fusion Protein Ag8610 |
Conjugate |
Unconjugated
|
Form |
Liquid |
Concentration |
1000 µg/mL |
Purification |
Protein G |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Aliquoting is unnecessary for -20°C storage.
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 2; Dimethylaniline oxidase 2; flavin containing monooxygenase 2; flavin containing monooxygenase 2 (non-functional); FMO 1B1; FMO 2; FMO, pulmonary; Pulmonary flavin-containing monooxygenase 2
Gene Aliases: 2310008D08Rik; 2310042I22Rik; AW107733; FMO1B1; FMO2
UniProt ID: (Human) Q99518, (Mouse) Q8K2I3
Entrez Gene ID: (Pig) 100525884, (Human) 2327, (Mouse) 55990
Molecular Function:
oxidoreductase
oxygenase
metabolite interconversion enzyme
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