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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
Assay-dependent | - |
Immunocytochemistry (ICC/IF) |
Assay-dependent | - |
ELISA (ELISA) |
Assay-dependent | - |
Immunoprecipitation (IP) |
25 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Fruit fly |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
6A15 |
Immunogen |
His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
0.1% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2896814 |
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cg 6203 gene product from transcript cg6203-rc; CG6203-PA; CG6203-PB; CG6203-PC; CG6203-PD; CG6203-PE; CG6203-PF; CG6203-PG; CG6203-PH; CG6203-PI; CG6203-PJ; CG6203-PK; dFMR; dFMR1; drosophila fragile X mental retardation protein; Fmr1-PA; Fmr1-PB; Fmr1-PC; Fmr1-PD; Fmr1-PE; Fmr1-PF; Fmr1-PG; Fmr1-PH; Fmr1-PI; Fmr1-PJ; Fmr1-PK; fragile X; fragile X mental retardation; fragile X mental retardation 1; fragile X mental retardation gene; fragile X mental retardation protein; fragile X mental retardation protein 1; fragile X mental retardation related 1; Fragile X messenger ribonucleoprotein 1 homolog; fragile X protein; fragile x related; fragile X related protein; fragile X retardation 1 protein; fragile X-related; fragile-X; Fragile-X mental retardation 1; Fragile-X mental retardation protein; Fragile-X-related; FXR; MGC87458
Gene Aliases: AT24755; BcDNA:GM08679; CG6203; dFMR; DFmr1; DFMRP; dFXR; dFXR1; dFXRP; Dmel\CG6203; Dmel_CG6203; dmfr1; EP(3)3517; FMR; FMR1; FMRP; FXR
UniProt ID: (Fruit fly) Q9NFU0
Entrez Gene ID: (Fruit fly) 37528
Molecular Function:
translation factor
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