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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 141 and 322 of Human FOX2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30681 targets FOX2 in WB applications and shows reactivity with Human samples.
The PA5-30681 immunogen is recombinant protein fragment corresponding to a region within amino acids 141 and 322 of Human FOX2.
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dJ106I20.3; Fox-1 homolog B; fox-1 homologue; Fox-2; FOX2; fxh; Hexaribonucleotide-binding protein 2; HNRBP2; HRNBP2; RBM9; Repressor of tamoxifen transcriptional activity; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding motif protein 9; RNA-binding protein 9; RTA
dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBFOX2; RBM9; RTA