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Product Details
H00002295-M04
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2G10
Immunogen
FOXF2 (NP_001443, 346 a.a. approximately 443 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: SPYLKQPPAL TPSSNPAASA GLHSSMSSYS LEQSYLHQNA REDLSVGLPR YQHHSTPVCD RKDFVLNFNG ISSFHPSASG SYYHHHHQSV CQDIKPCV
Target Information
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Forkhead box protein F2; forkhead homolog 20; forkhead-like 6; Forkhead-related activator 2; Forkhead-related protein FKHL6; Forkhead-related transcription factor 2; FREAC-2; Protein LUN
Gene Aliases: Fkh20; FKHL6; FOXF2; FREAC-2; FREAC2; LUN
UniProt ID: (Human) Q12947, (Mouse) O54743
Entrez Gene ID: (Human) 2295, (Mouse) 14238
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor binding
sequence-specific DNA binding
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
extracellular matrix organization
establishment of planar polarity of embryonic epithelium
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract development
embryonic camera-type eye morphogenesis
genitalia development
palate development
epithelial to mesenchymal transition
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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