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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Amino acids 242-655 of FKHR expressed in E. coli.|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||0.1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-23236 detects FKHR in Human samples.
MA1-23236 has been successfully used in Western Blot procedures. Predicted molecular weight of approximately 70 kDa. Positive control of Cos 1 cells transfected with human FKHR suggested.
MA1-23236 immunogen corresponds to Amino acids 242-655 of FKHR expressed in E. coli.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
FKHR recognizes FKHR (ForKHead in Rhabdomyosarcoma), a 70a protein, which is one member in a subfamily of the forkhead homeotic gene family of transcription factors. Recent experiments have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FKH1; FKHR; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; FOXO1A
FKH1; FKHR; FOXO1; FOXO1A