Product References
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice.
Frontiers in immunology
Zhu X,Li Q,George V,Spanoudis C,Gilkes C,Shrestha N,Liu B,Kong L,You L,Echeverri C,Li L,Wang Z,Chaturvedi P,Muniz GJ,Egan JO,Rhode PR,Wong HC
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Feb 13 00:00:00 EST 2023
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice.
Frontiers in immunology
Zhu X,Li Q,George V,Spanoudis C,Gilkes C,Shrestha N,Liu B,Kong L,You L,Echeverri C,Li L,Wang Z,Chaturvedi P,Muniz GJ,Egan JO,Rhode PR,Wong HC
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Feb 13 00:00:00 EST 2023
Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain.
Journal of neuroinflammation
Xu B,Shimauchi-Ohtaki H,Yoshimoto Y,Sadakata T,Ishizaki Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Tue Jan 17 00:00:00 EST 2023
Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain.
Journal of neuroinflammation
Xu B,Shimauchi-Ohtaki H,Yoshimoto Y,Sadakata T,Ishizaki Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Tue Jan 17 00:00:00 EST 2023
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Journal for immunotherapy of cancer
Graziano V,Dannhorn A,Hulme H,Williamson K,Buckley H,Karim SA,Wilson M,Lee SY,Kaistha BP,Islam S,Thaventhiran JED,Richards FM,Goodwin R,Brais R,Morton JP,Dovedi SJ,Schuller AG,Eyles J,Jodrell DI
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry (Paraffin)
Tue Aug 01 00:00:00 EDT 2023
Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance.
Inflammopharmacology
Shahine Y,El-Aal SAA,Reda AM,Sheta E,Atia NM,Abdallah OY,Ibrahim SSA
14-5773-82 was used in Immunohistochemistry to develop and characterise diosmin nanocrystals using anti-solvent precipitation technique to be used for topical treatment of psoriasis.
Thu Jun 01 00:00:00 EDT 2023
Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA.
Frontiers in immunology
Celesti F,Gatta A,Shallak M,Chiaravalli AM,Cerati M,Sessa F,Accolla RS,Forlani G
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Mar 31 00:00:00 EDT 2023
Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA.
Frontiers in immunology
Celesti F,Gatta A,Shallak M,Chiaravalli AM,Cerati M,Sessa F,Accolla RS,Forlani G
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Mar 31 00:00:00 EDT 2023
Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease.
Nature communications
Choi BJ,Park MH,Park KH,Han WH,Yoon HJ,Jung HY,Hong JY,Chowdhury MR,Kim KY,Lee J,Song IS,Pang M,Choi MK,Gulbins E,Reichel M,Kornhuber J,Hong CW,Kim C,Kim SH,Schuchman EH,Jin HK,Bae JS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism.
ImmunoHorizons
Arwood ML,Sun IH,Patel CH,Sun IM,Oh MH,Bettencourt IA,Claiborne MD,Chan-Li Y,Zhao L,Waickman AT,Mavrothalassitis O,Wen J,Aja S,Powell JD
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2023
Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.
Frontiers in immunology
Schwarz A,Philippsen R,Piticchio SG,Hartmann JN,Häsler R,Rose-John S,Schwarz T
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2023
SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis.
Cell communication and signaling : CCS
Lee AR,Woo JS,Lee SY,Lee YS,Jung J,Lee CR,Park SH,Cho ML
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2023
IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.
The Journal of experimental medicine
Reijers ILM,Rao D,Versluis JM,Menzies AM,Dimitriadis P,Wouters MW,Spillane AJ,Klop WMC,Broeks A,Bosch LJW,Lopez-Yurda M,van Houdt WJ,Rawson RV,Grijpink-Ongering LG,Gonzalez M,Cornelissen S,Bouwman J,Sanders J,Plasmeijer E,Elshot YS,Scolyer RA,van de Wiel BA,Peeper DS,van Akkooi ACJ,Long GV,Blank CU
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects.
Cell reports. Medicine
Ahmadi AR,Atiee G,Chapman B,Reynolds L,Sun J,Cameron AM,Wesson RN,Burdick JF,Sun Z
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2023
The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity.
International journal of inflammation
Bourebaba L,Serwotka-Suszczak A,Bourebaba N,Zyzak M,Marycz K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Oct 10 00:00:00 EDT 2023
TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions.
Frontiers in immunology
O'Neill TJ,Gewies A,Seeholzer T,Krappmann D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Chinese medicine
Pu S,Yang Z,Zhang X,Li M,Han N,Yang X,He J,Yu G,Meng X,Jia Q,Shao H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Hypertonic Salt Solution Enhances Inflammatory Responses in Cultured Splenic T-Cells from Dahl Salt-Sensitive Rats but Not Dahl Salt-Resistant Rats.
Journal of cardiovascular development and disease
Jang S,Kim JY,Kim CW,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2023
Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction.
Phytotherapy research : PTR
Tian CX,Li MY,Shuai XX,Jiang F,Dong YL,Gui Y,Zhang ZL,Qin RJ,Kang ZY,Lin L,Sarapultsev A,Wu B,Luo SS,Hu DS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity.
Nature communications
Read KA,Jones DM,Pokhrel S,Hales EDS,Varkey A,Tuazon JA,Eisele CD,Abdouni O,Saadey A,Leonard MR,Warren RT,Powell MD,Boss JM,Hemann EA,Yount JS,Xin G,Ghoneim HE,Lio CJ,Freud AG,Collins PL,Oestreich KJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma.
Nature cancer
Zheng C,Snow BE,Elia AJ,Nechanitzky R,Dominguez-Brauer C,Liu S,Tong Y,Cox MA,Focaccia E,Wakeham AC,Haight J,Tobin C,Hodgson K,Gill KT,Ma W,Berger T,Heikenwälder M,Saunders ME,Fortin J,Leung SY,Mak TW
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2023
Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.
Cancer discovery
Herrera FG,Ronet C,Ochoa de Olza M,Barras D,Crespo I,Andreatta M,Corria-Osorio J,Spill A,Benedetti F,Genolet R,Orcurto A,Imbimbo M,Ghisoni E,Navarro Rodrigo B,Berthold DR,Sarivalasis A,Zaman K,Duran R,Dromain C,Prior J,Schaefer N,Bourhis J,Dimopoulou G,Tsourti Z,Messemaker M,Smith T,Warren SE,Foukas P,Rusakiewicz S,Pittet MJ,Zimmermann S,Sempoux C,Dafni U,Harari A,Kandalaft LE,Carmona SJ,Dangaj Laniti D,Irving M,Coukos G
14-5773-82 was used in Immunohistochemistry (Paraffin) to report that low-dose radiotherapy (LDRT) of murine tumors promotes T-cell infiltration and enables responsiveness to combinatorial immunotherapy in an IFN-dependent manner.
Sat Jan 01 00:00:00 EST 2022
Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation.
The Journal of clinical investigation
Failer T,Amponsah-Offeh M,Neuwirth A,Kourtzelis I,Subramanian P,Mirtschink P,Peitzsch M,Matschke K,Tugtekin SM,Kajikawa T,Li X,Steglich A,Gembardt F,Wegner AC,Hugo C,Hajishengallis G,Chavakis T,Deussen A,Todorov V,Kopaliani I
14-5773-82 was used in Flow Cytometry to identify DEL-1 as a potential therapeutic factor.
Tue Mar 15 00:00:00 EDT 2022
Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.
Cell death and differentiation
Musiu C,Caligola S,Fiore A,Lamolinara A,Frusteri C,Del Pizzo FD,De Sanctis F,Canè S,Adamo A,Hofer F,Barouni RM,Grilli A,Zilio S,Serafini P,Tacconelli E,Donadello K,Gottin L,Polati E,Girelli D,Polidoro I,Iezzi PA,Angelucci D,Capece A,Chen Y,Shi ZL,Murray PJ,Chilosi M,Amit I,Bicciato S,Iezzi M,Bronte V,Ugel S
14-5773-82 was used in Immunohistochemistry to show that as STAT3-targeting approaches relieved inflammation, immune disorders, and organ failures in these mice, targeted intervention towards this pathway could suppress the lethal CRS inflammatory state.
Tue Feb 01 00:00:00 EST 2022
Trivalent chromium supplementation ameliorates adjuvant induced rheumatoid arthritis through up-regulation of FOXP3 and decrease in synovial Cathepsin G expression.
Inflammopharmacology
Hassouna SS,Sheta E,Zaki I,Harby SA,Allam EA
14-5773-82 was used in Immunohistochemistry to conclude that trivalent chromium (Cr (III)) is promising in treating RA and it lacks some side efects of accustomed immune-modulatory agents including prednisolone.
Thu Dec 01 00:00:00 EST 2022
miR-126 ameliorates multiple organ dysfunction in septic rats by regulating the differentiation of Th17/Treg.
Molecular biology reports
Zou Q,Liu C,Hu N,Wang W,Wang H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss.
Cell death & disease
Mejía-Hernández JO,Keam SP,Saleh R,Muntz F,Fox SB,Byrne D,Kogan A,Pang L,Huynh J,Litchfield C,Caramia F,Lozano G,He H,You JM,Sandhu S,Williams SG,Haupt Y,Haupt S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Sep 08 00:00:00 EDT 2022
Comparative analysis of the immune response to RFA and cryoablation in a colon cancer mouse model.
Scientific reports
Mauda-Havakuk M,Hawken NM,Owen JW,Mikhail AS,Saxena A,Karim B,Wakim PG,Pritchard WF,Karanian JW,Wood BJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Oct 29 00:00:00 EDT 2022
Live or Heat-Killed Lactobacillus rhamnosus Aerosolization Decreases Adenomatous Lung Cancer Development in a Mouse Carcinogen-Induced Tumor Model.
International journal of molecular sciences
Le Noci V,Bernardo G,Manenti G,Infante G,Khaleghi Hashemian D,Minoli L,Canesi S,Bianchi F,Triulzi T,Arioli S,De Cecco L,Guglielmetti S,Ambrogi F,Recordati C,Gagliano N,Tagliabue E,Sommariva M,Sfondrini L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry (Paraffin)
Sat Oct 22 00:00:00 EDT 2022
Attenuated Salmonella potentiate PD-L1 blockade immunotherapy in a preclinical model of colorectal cancer.
Frontiers in immunology
Al-Saafeen BH,Al-Sbiei A,Bashir G,Mohamed YA,Masad RJ,Fernandez-Cabezudo MJ,Al-Ramadi BK
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jan 09 00:00:00 EST 2023
Attenuated Salmonella potentiate PD-L1 blockade immunotherapy in a preclinical model of colorectal cancer.
Frontiers in immunology
Al-Saafeen BH,Al-Sbiei A,Bashir G,Mohamed YA,Masad RJ,Fernandez-Cabezudo MJ,Al-Ramadi BK
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jan 09 00:00:00 EST 2023
Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer.
Molecular therapy oncolytics
Araki H,Tazawa H,Kanaya N,Kajiwara Y,Yamada M,Hashimoto M,Kikuchi S,Kuroda S,Yoshida R,Umeda Y,Urata Y,Kagawa S,Fujiwara T
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Dec 15 00:00:00 EST 2022
The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model.
Bioengineering & translational medicine
Lin A,De Backer J,Quatannens D,Cuypers B,Verswyvel H,De La Hoz EC,Ribbens B,Siozopoulou V,Van Audenaerde J,Marcq E,Lardon F,Laukens K,Vanlanduit S,Smits E,Bogaerts A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Novel peptide-based vaccine targeting heat shock protein 90 induces effective antitumor immunity in a HER2+ breast cancer murine model.
Journal for immunotherapy of cancer
Kang J,Lee HJ,Lee J,Hong J,Hong Kim Y,Disis ML,Gim JA,Park KH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Novel peptide-based vaccine targeting heat shock protein 90 induces effective antitumor immunity in a HER2+ breast cancer murine model.
Journal for immunotherapy of cancer
Kang J,Lee HJ,Lee J,Hong J,Hong Kim Y,Disis ML,Gim JA,Park KH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Withdrawn: Parecoxib inhibits inflammatory responses in a mouse model of sepsis.
FEBS open bio
No authors listed
14-5773 was used in Flow cytometry/Cell sorting to suggest that Parecoxib inhibits the inflammatory response and has protective effects against sepsis in mice, and may have potential as a novel therapeutic method for treating sepsis.
Sat Jan 01 00:00:00 EST 2022
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Cancer cell
Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Twelve-week high-fat diet for improving adverse ventricular remodeling post-myocardial infarction by alleviating local inflammation.
Annals of translational medicine
Yang J,Mai B,Su Y,Liang S,Su Z,Chen Y,Xie S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
Protocol to assess cell-intrinsic regulatory mechanisms using an ex vivo murine T cell polarization and co-culture system.
STAR protocols
Ma S,Hernandez JE,Huang WJM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Sep 16 00:00:00 EDT 2022
Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.
Cancers
Ponzo M,Debesset A,Cossutta M,Chalabi-Dchar M,Houppe C,Pilon C,Nicolas-Boluda A,Meunier S,Raineri F,Thiolat A,Nicolle R,Maione F,Brundu S,Cojocaru CF,Bouvet P,Bousquet C,Gazeau F,Tournigand C,Courty J,Giraudo E,Cohen JL,Cascone I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2022
Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Cell reports
West HC,Davies J,Henderson S,Adegun OK,Ward S,Ferrer IR,Tye CA,Vallejo AF,Jardine L,Collin M,Polak ME,Bennett CL
14-5773-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to demonstrate that pathology initiates dermis-specific macrophage differentiation and show that aGVHD-primed macrophages continue to dominate the dermal compartment at the relative expense of quiescent MHCIIint cells.
Tue May 17 00:00:00 EDT 2022
An immunocompetent rectal cancer model to study radiation therapy.
Cell reports methods
Kim JK,Wu C,Del Latto M,Gao Y,Choi SH,Kierstead M,Gabriel Sauvé CE,Firat C,Perez AC,Sillanpaa J,Chen CT,Lawrence KE,Paty PB,Barriga FM,Wilkinson JE,Shia J,Sawyers CL,Lowe SW,García-Aguilar J,Romesser PB,Smith JJ
14-5773-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to describe a mouse model of rectal cancer (RC) involving rapid tumor organoid engraftment via orthotopic transplantation in an immunocompetent setting.
Mon Dec 19 00:00:00 EST 2022
A multi-omic single cell sequencing approach to develop a CD8 T cell specific gene signature for anti-PD1 response in solid tumors.
International journal of cancer
Kumar N,Papillon-Cavanagh S,Tang H,Wang S,Stromko C,Ho CP,Soni-Sheth S,Vasquez-Grinnell S,Broz ML,Tenney DJ,Wichroski MJ,Walsh AM,Hu Y,Benci JL
14-5773-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to highlight the value of leveraging single-cell assays to dissect heterogeneous tumor and immune subsets and define cell-type specific transcriptomic biomarkers of immune checkpoint blockade (ICB) response.
Thu Dec 01 00:00:00 EST 2022
First Report of TTSuV1 in Domestic Swiss Pigs.
Viruses
Polster S,Lechmann J,Lienhard J,Peltzer D,Prähauser B,Bachofen C,Seehusen F
14-5773-82 was used in Immunohistochemistry to investigate the presence of Torque teno sus viruses (TTSuV1 and k2) in porcine brain tissue and other organs.
Fri Apr 22 00:00:00 EDT 2022
FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape.
Theranostics
Wu L,Xu Y,Zhao H,Zhou Y,Chen Y,Yang S,Lei J,Zhang J,Wang J,Wu Y,Li Y
14-5773-82 was used in Flow Cytometry to uncover an unrecognized regulatory role of the FcγRIIB in abnormal differentiation of MDSCs during cancer development and suggest a potential therapeutic target for anti-tumor therapy.
Thu Mar 10 00:00:00 EST 2022
Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.
JCI insight
Klaus T,Wilson AS,Vicari E,Hadaschik E,Klein M,Helbich SSC,Kamenjarin N,Hodapp K,Schunke J,Haist M,Butsch F,Probst HC,Enk AH,Mahnke K,Waisman A,Bednarczyk M,Bros M,Bopp T,Grabbe S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Dec 22 00:00:00 EST 2022
Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice.
Frontiers in immunology
Kraemer AN,Schäfer AL,Sprenger DTL,Sehnert B,Williams JP,Luo A,Riechert L,Al-Kayyal Q,Dumortier H,Fauny JD,Winter Z,Heim K,Hofmann M,Herrmann M,Heine G,Voll RE,Chevalier N
14-5773-82 was used in Flow Cytometry to reveal that low VD intake promotes lupus pathology, likely via the deviation of adaptive immunity, and suggests that the correction of VD deficiency might not only exert beneficial functions by preventing osteoporosis but also serve as an important module in prophylaxis and as an add-on in the treatment of lupus and possibly other immune-mediated diseases.
Fri Dec 16 00:00:00 EST 2022
Does physical exercise improve or deteriorate treatment of multiple sclerosis with mitoxantrone? Experimental autoimmune encephalomyelitis study in rats.
BMC neuroscience
El-Emam MA,El Achy S,Abdallah DM,El-Abhar HS,Gowayed MA
14-5773-82 was used in Immunohistochemistry to show that exercise worsened the mitoxantrone effect on EAE score, Bcl2 and Bax. Mitoxantrone alone decreased EAE/demyelination/inflammation scores, Foxp3 immunoreactivity, and interleukin-6, while increased the re-myelination marker BDNF without any change in tumor necrosis factor-α.
Sat Mar 05 00:00:00 EST 2022
Black raspberry extract inhibits regulatory T-cell activity in a murine model of head and neck squamous cell carcinoma chemoprevention.
Frontiers in immunology
Ryan NM,Lamenza FF,Upadhaya P,Pracha H,Springer A,Swingler M,Siddiqui A,Oghumu S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Western Blot
Mon Aug 29 00:00:00 EDT 2022
Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.
Cell reports. Medicine
Uceda-Castro R,Margarido AS,Cornet L,Vegna S,Hahn K,Song JY,Putavet DA,van Geldorp M,Çitirikkaya CH,de Keizer PLJ,Ter Beek LC,Borst GR,Akkari L,van Tellingen O,Broekman MLD,Vennin C,van Rheenen J
14-5773-82 was used in Immunohistochemistry to demonstrate that induction of senescence with doxorubicin improves the efficacy of immunotherapy with anti-PD1 in breast cancer brain metastasis (BCBM) in a CD8 T cell-dependent manner, thereby providing an optimized strategy to introduce immune-based treatments in this lethal disease.
Tue Nov 15 00:00:00 EST 2022
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.
Immunity
Harb H,Benamar M,Lai PS,Contini P,Griffith JW,Crestani E,Schmitz-Abe K,Chen Q,Fong J,Marri L,Filaci G,Del Zotto G,Pishesha N,Kolifrath S,Broggi A,Ghosh S,Gelmez MY,Oktelik FB,Cetin EA,Kiykim A,Kose M,Wang Z,Cui Y,Yu XG,Li JZ,Berra L,Stephen-Victor E,Charbonnier LM,Zanoni I,Ploegh H,Deniz G,De Palma R,Chatila TA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
The Journal of experimental medicine
Wirasinha RC,Davies AR,Srivastava M,Sheridan JM,Sng XYX,Delmonte OM,Dobbs K,Loh KL,Miosge LA,Lee CE,Chand R,Chan A,Yap JY,Keller MD,Chen K,Rossjohn J,La Gruta NL,Vinuesa CG,Reid HH,Lionakis MS,Notarangelo LD,Gray DHD,Goodnow CC,Cook MC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells.
Genes & diseases
Yang L,Jing Y,Kang D,Jiang P,Li N,Zhou X,Chen Y,Westerberg LS,Liu C
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Thymic atrophy creates holes in Treg-mediated immuno-regulation via impairment of an antigen-specific clone.
Immunology
Thomas R,Oh J,Wang W,Su DM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer.
Cancer immunology, immunotherapy : CII
Shi Y,Fu Y,Zhang X,Zhao G,Yao Y,Guo Y,Ma G,Bai S,Li H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo.
The American journal of pathology
Li M,McGhee EM,Shinno L,Lee K,Lin YL
14-5773-82 was used in Immunohistochemistry to show that butyrate treatment changed the property of HPV16 E6/E7-immortalized keratinocytes.
Fri Oct 01 00:00:00 EDT 2021
Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis.
Journal of immunology (Baltimore, Md. : 1950)
Bianchi A,Marchetti L,Hall Z,Lemos H,Vacca M,Paish H,Green K,Elliott B,Tiniakos D,Passos JF,Jurk D,Mann DA,Wilson CL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Feb 15 00:00:00 EST 2021
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Chen L,Bai J,Peng D,Gao Y,Cai X,Zhang J,Tang S,Niu L,Sun Y,Lou F,Zhou H,Yin Q,Wang Z,Sun L,Du X,Xu Z,Wang H,Li Q,Wang H
14-5773-82 was used in Flow Cytometry to characterise the target and mechanism of an acetylated beta-boswellic acid derivative termed SZB120, and evaluate the anti-inflammatory activities in vitro and in vivo.
Mon Mar 01 00:00:00 EST 2021
Type of chemotherapy has substantial effects on the immune system in ovarian cancer.
Translational oncology
Vankerckhoven A,Baert T,Riva M,De Bruyn C,Thirion G,Vandenbrande K,Ceusters J,Vergote I,Coosemans A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
Type of chemotherapy has substantial effects on the immune system in ovarian cancer.
Translational oncology
Vankerckhoven A,Baert T,Riva M,De Bruyn C,Thirion G,Vandenbrande K,Ceusters J,Vergote I,Coosemans A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
Tregs-derived interleukin 35 attenuates endothelial proliferation through STAT1 in pulmonary hypertension.
Annals of translational medicine
Wan N,Rong W,Zhu W,Jia D,Bai P,Liu G,Wan Q,Lyu A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Tue Jun 01 00:00:00 EDT 2021
Tregs-derived interleukin 35 attenuates endothelial proliferation through STAT1 in pulmonary hypertension.
Annals of translational medicine
Wan N,Rong W,Zhu W,Jia D,Bai P,Liu G,Wan Q,Lyu A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Tue Jun 01 00:00:00 EDT 2021
Local Anti-PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model.
Cancer prevention research (Philadelphia, Pa.)
Shi Y,Xie TX,Leach DG,Wang B,Young S,Osman AA,Sikora AG,Ren X,Hartgerink JD,Myers JN,Rangel R
14-5773-82 was used in Immunohistochemistry to combine biomaterials loaded with an immunotherapeutic agent preventing oral cancer progression.
Sun Aug 01 00:00:00 EDT 2021
Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats.
BioMed research international
Kim JY,Lee E,Koo S,Kim CW,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue May 25 00:00:00 EDT 2021
Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats.
BioMed research international
Kim JY,Lee E,Koo S,Kim CW,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue May 25 00:00:00 EDT 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis.
Journal for immunotherapy of cancer
Kim S,Kim SA,Nam GH,Hong Y,Kim GB,Choi Y,Lee S,Cho Y,Kwon M,Jeong C,Kim S,Kim IS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis.
Journal for immunotherapy of cancer
Kim S,Kim SA,Nam GH,Hong Y,Kim GB,Choi Y,Lee S,Cho Y,Kwon M,Jeong C,Kim S,Kim IS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Faslpr Mice.
Cells
Schmidtke L,Meineck M,Saurin S,Otten S,Gather F,Schrick K,Käfer R,Roth W,Kleinert H,Weinmann-Menke J,Pautz A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Nov 14 00:00:00 EST 2021
STAT3 Signalling via the IL-6ST/gp130 Cytokine Receptor Promotes Epithelial Integrity and Intestinal Barrier Function during DSS-Induced Colitis.
Biomedicines
Pang L,Huynh J,Alorro MG,Li X,Ernst M,Chand AL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Feb 12 00:00:00 EST 2021
STAT3 Signalling via the IL-6ST/gp130 Cytokine Receptor Promotes Epithelial Integrity and Intestinal Barrier Function during DSS-Induced Colitis.
Biomedicines
Pang L,Huynh J,Alorro MG,Li X,Ernst M,Chand AL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Feb 12 00:00:00 EST 2021
Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu X,Jiang J,Liao YP,Tang I,Zheng E,Qiu W,Lin M,Wang X,Ji Y,Mei KC,Liu Q,Chang CH,Wainberg ZA,Nel AE,Meng H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis.
Cancers
Bartlett AQ,Pennock ND,Klug A,Schedin P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Apr 03 00:00:00 EDT 2021
Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis.
Cancers
Bartlett AQ,Pennock ND,Klug A,Schedin P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Apr 03 00:00:00 EDT 2021
Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells.
Communications biology
Vito A,Salem O,El-Sayes N,MacFawn IP,Portillo AL,Milne K,Harrington D,Ashkar AA,Wan Y,Workenhe ST,Nelson BH,Bruno TC,Mossman KL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jul 12 00:00:00 EDT 2021
Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma.
Cell reports. Medicine
Chao JL,Korzinkin M,Zhavoronkov A,Ozerov IV,Walker MT,Higgins K,Lingen MW,Izumchenko E,Savage PA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Sep 21 00:00:00 EDT 2021
Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma.
Cell reports. Medicine
Chao JL,Korzinkin M,Zhavoronkov A,Ozerov IV,Walker MT,Higgins K,Lingen MW,Izumchenko E,Savage PA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Sep 21 00:00:00 EDT 2021
Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure.
iScience
Fotheringham AK,Solon-Biet SM,Bielefeldt-Ohmann H,McCarthy DA,McMahon AC,Ruohonen K,Li I,Sullivan MA,Whiddett RO,Borg DJ,Cogger VC,Ballard WO,Turner N,Melvin RG,Raubenheimer D,Le Couteur DG,Simpson SJ,Forbes JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Fri Nov 19 00:00:00 EST 2021
A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy.
Frontiers in immunology
Wang Y,Gu T,Tian X,Li W,Zhao R,Yang W,Gao Q,Li T,Shim JH,Zhang C,Liu K,Lee MH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Sep 29 00:00:00 EDT 2021
A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy.
Frontiers in immunology
Wang Y,Gu T,Tian X,Li W,Zhao R,Yang W,Gao Q,Li T,Shim JH,Zhang C,Liu K,Lee MH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Sep 29 00:00:00 EDT 2021
Treatment with the Probiotic Product Aviguard® Alleviates Inflammatory Responses during Campylobacter jejuni-Induced Acute Enterocolitis in Mice.
International journal of molecular sciences
Heimesaat MM,Weschka D,Mousavi S,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Jun 22 00:00:00 EDT 2021
Development of a Multiplex Immunohistochemistry Workflow to Investigate the Immune Microenvironment in Mouse Models of Inflammatory Bowel Disease and Colon Cancer.
International journal of molecular sciences
Pang L,Ernst M,Huynh J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Oct 12 00:00:00 EDT 2021
CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells.
iScience
Qadir AS,Guégan JP,Ginestier C,Chaibi A,Bessede A,Charafe-Jauffret E,Macario M,Lavoué V,Rouge TM,Law C,Vilker J,Wang H,Stroup E,Schipma MJ,Bridgeman B,Murmann AE,Ji Z,Legembre P,Peter ME
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Nov 19 00:00:00 EST 2021
Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer.
Aging
Huang C,Li Z,Zhu J,Chen X,Hao Y,Yang R,Huang R,Zhou J,Wang Z,Xiao W,Zheng C,Wang Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Jan 17 00:00:00 EST 2021
Glucose Metabolism Reprogramming of Regulatory T Cells in Concanavalin A-Induced Hepatitis.
Frontiers in pharmacology
Huang C,Shen Y,Shen M,Fan X,Men R,Ye T,Yang L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Sep 18 00:00:00 EDT 2021
Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation.
Theranostics
Chen L,Chen H,Ye J,Ge Y,Wang H,Dai E,Ren J,Liu W,Ma C,Ju S,Guo ZS,Liu Z,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Aug 04 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Rodent Models of Spondyloarthritis Have Decreased White and Bone Marrow Adipose Tissue Depots.
Frontiers in immunology
Furesi G,Fert I,Beaufrère M,Araujo LM,Glatigny S,Baschant U,von Bonin M,Hofbauer LC,Horwood NJ,Breban M,Rauner M
14-5773-82 was used in Flow Cytometry to investigate the amount of white fat and bone marrow adipose tissue and how these link to chronic inflammatory spondyloarthritis.
Mon Oct 25 00:00:00 EDT 2021
Rodent Models of Spondyloarthritis Have Decreased White and Bone Marrow Adipose Tissue Depots.
Frontiers in immunology
Furesi G,Fert I,Beaufrère M,Araujo LM,Glatigny S,Baschant U,von Bonin M,Hofbauer LC,Horwood NJ,Breban M,Rauner M
14-5773-82 was used in Flow Cytometry to investigate the amount of white fat and bone marrow adipose tissue and how these link to chronic inflammatory spondyloarthritis.
Mon Oct 25 00:00:00 EDT 2021
Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
Gastroenterology
Gebert J,Gelincik O,Oezcan-Wahlbrink M,Marshall JD,Hernandez-Sanchez A,Urban K,Long M,Cortes E,Tosti E,Katzenmaier EM,Song Y,Elsaadi A,Deng N,Vilar E,Fuchs V,Nelius N,Yuan YP,Ahadova A,Sei S,Shoemaker RH,Umar A,Wei L,Liu S,Bork P,Edelmann W,von Knebel Doeberitz M,Lipkin SM,Kloor M
14-5773-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to test the hypothesis that recurrent FSP vaccination alone or in combination with NSAID treatment can promote anti-FSP adaptive immunity sufficiently to reduce intestinal tumor burden and prolong overall survival.
Fri Oct 01 00:00:00 EDT 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
IκB Kinase-β Regulates Neutrophil Recruitment Through Activation of STAT3 Signaling in the Esophagus.
Cellular and molecular gastroenterology and hepatology
Wiles KN,Alioto CM,Hodge NB,Clevenger MH,Tsikretsis LE,Lin FTJ,Tétreault MP
14-5773-82 was used in Flow Cytometry to report that IkkβcaEEC-KI mice have increased activation of epithelial Janus kinase 2/STAT3 signaling.
Mon Mar 28 00:00:00 EDT 2022
Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model.
Molecular cancer research : MCR
El Meskini R,Atkinson D,Kulaga A,Abdelmaksoud A,Gumprecht M,Pate N,Hayes S,Oberst M,Kaplan IM,Raber P,Van Dyke T,Sharan SK,Hollingsworth R,Day CP,Merlino G,Weaver Ohler Z
14-5773-82 was used in Immunohistochemistry to suggest that an anti-PD-L1-mediated melanoma regression response requires not only an expansion of the TCR repertoire that is unique to individual mice, but also tumor access to the appropriate TCRs.
Sun Aug 01 00:00:00 EDT 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells.
Cell reports
Matas-Rico E,Frijlink E,van der Haar Àvila I,Menegakis A,van Zon M,Morris AJ,Koster J,Salgado-Polo F,de Kivit S,Lança T,Mazzocca A,Johnson Z,Haanen J,Schumacher TN,Perrakis A,Verbrugge I,van den Berg JH,Borst J,Moolenaar WH
14-5773-82 was used in Flow cytometry/Cell sorting to highlight an unexpected role for the pro-metastatic ATX-LPAR axis in suppressing CD8+ T cell infiltration to impede anti-tumor immunity, suggesting new therapeutic opportunities.
Tue Nov 16 00:00:00 EST 2021
Anti-Pathogenic and Immune-Modulatory Effects of Peroral Treatment with Cardamom Essential Oil in Acute Murine Campylobacteriosis.
Microorganisms
Heimesaat MM,Mousavi S,Weschka D,Bereswill S
14-5773-82 was used in Immunohistochemistry to provide the first evidence that cardamom EO comprises a promising compound for the combat of acute campylobacteriosis and presumably prevention of post-infectious morbidities.
Thu Jan 14 00:00:00 EST 2021
Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus.
International journal of molecular sciences
Amend A,Wickli N,Schäfer AL,Sprenger DTL,Manz RA,Voll RE,Chevalier N
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jan 29 00:00:00 EST 2021
Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology.
Science advances
Da Mesquita S,Herz J,Wall M,Dykstra T,de Lima KA,Norris GT,Dabhi N,Kennedy T,Baker W,Kipnis J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
SPNS2 enables T cell egress from lymph nodes during an immune response.
Cell reports
Okuniewska M,Fang V,Baeyens A,Raghavan V,Lee JY,Littman DR,Schwab SR
14-5773-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to demonstrate that SPNS2 supplies the S1P that guides T cells out of LNs with an ongoing immune response.
Tue Jul 13 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Cell
Ruscetti M,Morris JP,Mezzadra R,Russell J,Leibold J,Romesser PB,Simon J,Kulick A,Ho YJ,Fennell M,Li J,Norgard RJ,Wilkinson JE,Alonso-Curbelo D,Sridharan R,Heller DA,de Stanchina E,Stanger BZ,Sherr CJ,Lowe SW
14-5773 was used in Immunohistochemistry-immunofluorescence to show that a combination of MEK and CDK4/6 inhibitors that target KRAS-directed oncogenic signaling can suppress PDAC proliferation through induction of retinoblastoma (RB) protein-mediated senescence.
Thu Apr 16 00:00:00 EDT 2020
Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance.
Cancer cell
Orgaz JL,Crosas-Molist E,Sadok A,Perdrix-Rosell A,Maiques O,Rodriguez-Hernandez I,Monger J,Mele S,Georgouli M,Bridgeman V,Karagiannis P,Lee R,Pandya P,Boehme L,Wallberg F,Tape C,Karagiannis SN,Malanchi I,Sanz-Moreno V
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jan 13 00:00:00 EST 2020
S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.
Gastroenterology
Willers M,Ulas T,Völlger L,Vogl T,Heinemann AS,Pirr S,Pagel J,Fehlhaber B,Halle O,Schöning J,Schreek S,Löber U,Essex M,Hombach P,Graspeuntner S,Basic M,Bleich A,Cloppenborg-Schmidt K,Künzel S,Jonigk D,Rupp J,Hansen G,Förster R,Baines JF,Härtel C,Schultze JL,Forslund SK,Roth J,Viemann D
14-5773-82 was used in immunohistochemistry (frozen) to study levels of S100A8-A9 in fecal samples (also called fecal calprotectin) from newborns and during infancy, and their effects on development of the intestinal microbiota and mucosal immune system.
Tue Dec 01 00:00:00 EST 2020
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
The Journal of clinical investigation
Webb LM,Sengupta S,Edell C,Piedra-Quintero ZL,Amici SA,Miranda JN,Bevins M,Kennemer A,Laliotis G,Tsichlis PN,Guerau-de-Arellano M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity.
The Journal of clinical investigation
Xiong Y,Wang L,Di Giorgio E,Akimova T,Beier UH,Han R,Trevisanut M,Kalin JH,Cole PA,Hancock WW
14-5773-80 was used in Immunocytochemistry to analyse the role in Tregs of the evolutionarily conserved CoREST complex, consisting of a scaffolding protein, Rcor1 or Rcor2, plus Hdac1 or Hdac2 and Lsd1 enzymes.
Wed Apr 01 00:00:00 EDT 2020
Metformin Abrogates Age-Associated Ovarian Fibrosis.
Clinical cancer research : an official journal of the American Association for Cancer Research
McCloskey CW,Cook DP,Kelly BS,Azzi F,Allen CH,Forsyth A,Upham J,Rayner KJ,Gray DA,Boyd RW,Murugkar S,Lo B,Trudel D,Senterman MK,Vanderhyden BC
14-5773-80 was used in Immunohistochemistry (Paraffin) to assess the effects of age and ovulation on the ovarian microenvironment underlie ovarian cancer risk.
Sat Feb 01 00:00:00 EST 2020
Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms.
Diabetes
Ward NC,Lui JB,Hernandez R,Yu L,Struthers M,Xie J,Santos Savio A,Dwyer CJ,Hsiung S,Yu A,Malek TR
14-5773 was used in Flow cytometry/Cell sorting to show that low-dose mouse IL-2/CD25 (mIL-2/CD25), but not an equivalent amount of IL-2, prevents the onset of diabetes in NOD mice and controls diabetes in hyperglycemic mice.
Sun Nov 01 00:00:00 EDT 2020
Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation.
Immunology
Kuehlwein JM,Borsche M,Korir PJ,Risch F,Mueller AK,Hübner MP,Hildner K,Hoerauf A,Dunay IR,Schumak B
14-5773 was used in Flow cytometry/Cell sorting to investigate the inflammatory immune responses to plasmodium parasite infections which lead to cerebral malaria using a mouse model.
Sat Feb 01 00:00:00 EST 2020
Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation.
Immunology
Kuehlwein JM,Borsche M,Korir PJ,Risch F,Mueller AK,Hübner MP,Hildner K,Hoerauf A,Dunay IR,Schumak B
14-5773 was used in Flow cytometry/Cell sorting to investigate the inflammatory immune responses to plasmodium parasite infections which lead to cerebral malaria using a mouse model.
Sat Feb 01 00:00:00 EST 2020
An Antibody-Tumor Necrosis Factor Fusion Protein that Synergizes with Oxaliplatin for Treatment of Colorectal Cancer.
Molecular cancer therapeutics
Bajic D,Chester K,Neri D
14-5773-82 was used in Immunocytochemistry to provide a rationale for the possible clinical use of oxaliplatin in combination with fully human antibody-TNF fusions.
Tue Dec 01 00:00:00 EST 2020
Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive but not Dahl salt-resistant rats.
Disease models & mechanisms
Lee E,Kim N,Kang J,Yoon S,Lee HA,Jung H,Kim SH,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed May 27 00:00:00 EDT 2020
Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive but not Dahl salt-resistant rats.
Disease models & mechanisms
Lee E,Kim N,Kang J,Yoon S,Lee HA,Jung H,Kim SH,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed May 27 00:00:00 EDT 2020
Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4+ T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Liu H,Wilson KR,Schriek P,Macri C,Blum AB,Francis L,Heinlein M,Nataraja C,Harris J,Jones SA,Gray DHD,Villadangos JA,Mintern JD
14-5773-82 was used in Immunohistochemistry to conclude that MHC II ubiquitination in specific APC types does not have a major impact on the conventional CD4+ T cell compartment but is important for Treg development.
Tue Sep 01 00:00:00 EDT 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
A novel inhibitory role of microRNA-224 in particulate matter 2.5-induced asthmatic mice by inhibiting TLR2.
Journal of cellular and molecular medicine
Li P,Wang J,Guo F,Zheng B,Zhang X
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
A Phase I, Dose Escalation, Single Dose Trial of Oral Attenuated Salmonella typhimurium Containing Human IL-2 in Patients With Metastatic Gastrointestinal Cancers.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Gniadek TJ,Augustin L,Schottel J,Leonard A,Saltzman D,Greeno E,Batist G
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Japanese Kampo Medicine Juzentaihoto Enhances Antitumor Immunity in CD1d-/- Mice Lacking NKT Cells.
Integrative cancer therapies
Takaku S,Shimizu M,Takahashi H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Mar 23 00:00:00 EDT 2020
Alcohol-Induced Immune Dysregulation in the Colon Is Diurnally Variable.
Visceral medicine
Grumish EL,Armstrong AR,Voigt RM,Forsyth CB,Bishehsari F
14-5773-82 was used in Immunocytochemistry to investigate the diurnal variation of lymphocyte infiltration in the colonic mucosa in response to alcohol.
Mon Jun 01 00:00:00 EDT 2020
Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro.
Veterinary ophthalmology
Saldinger LK,Nelson SG,Bellone RR,Lassaline M,Mack M,Walker NJ,Borjesson DL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro.
Veterinary ophthalmology
Saldinger LK,Nelson SG,Bellone RR,Lassaline M,Mack M,Walker NJ,Borjesson DL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Sep 30 00:00:00 EDT 2020
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.
Cell reports
Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Tue Jan 21 00:00:00 EST 2020
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.
Cell reports
Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Tue Jan 21 00:00:00 EST 2020
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.
Cell reports
Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Tue Jan 21 00:00:00 EST 2020
Immunopathogenesis of canine chronic ulcerative stomatitis.
PloS one
Anderson JG,Kol A,Bizikova P,Stapelton BP,Ford K,Villarreal A,Jimenez RJ,Vasilatis D,Murphy BG
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Mon Apr 20 00:00:00 EDT 2020
Immunopathogenesis of canine chronic ulcerative stomatitis.
PloS one
Anderson JG,Kol A,Bizikova P,Stapelton BP,Ford K,Villarreal A,Jimenez RJ,Vasilatis D,Murphy BG
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Mon Apr 20 00:00:00 EDT 2020
Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10-/- Mice.
Pathogens (Basel, Switzerland)
Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Dec 23 00:00:00 EST 2020
Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota.
Pathogens (Basel, Switzerland)
Kløve S,Genger C,Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota.
Pathogens (Basel, Switzerland)
Kløve S,Genger C,Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis.
Cellular and molecular gastroenterology and hepatology
Bishehsari F,Engen PA,Voigt RM,Swanson G,Shaikh M,Wilber S,Naqib A,Green SJ,Shetuni B,Forsyth CB,Saadalla A,Osman A,Hamaker BR,Keshavarzian A,Khazaie K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed May 05 00:00:00 EDT 2021
A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey.
Immunity, inflammation and disease
van Sadelhoff JHJ,Hogenkamp A,Wiertsema SP,Harthoorn LF,Loonstra R,Hartog A,Garssen J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey.
Immunity, inflammation and disease
van Sadelhoff JHJ,Hogenkamp A,Wiertsema SP,Harthoorn LF,Loonstra R,Hartog A,Garssen J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey.
Immunity, inflammation and disease
van Sadelhoff JHJ,Hogenkamp A,Wiertsema SP,Harthoorn LF,Loonstra R,Hartog A,Garssen J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey.
Immunity, inflammation and disease
van Sadelhoff JHJ,Hogenkamp A,Wiertsema SP,Harthoorn LF,Loonstra R,Hartog A,Garssen J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Sep 29 00:00:00 EDT 2020
The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Sep 29 00:00:00 EDT 2020
Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy.
FASEB bioAdvances
Wijesekera DPH,Yuba E,De Silva NH,Watanabe SI,Tsukamoto M,Ichida C,Izawa T,Itoh K,Kanegi R,Hatoya S,Yamate J,Inaba T,Sugiura K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Jan 01 00:00:00 EST 2020
Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy.
FASEB bioAdvances
Wijesekera DPH,Yuba E,De Silva NH,Watanabe SI,Tsukamoto M,Ichida C,Izawa T,Itoh K,Kanegi R,Hatoya S,Yamate J,Inaba T,Sugiura K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Jan 01 00:00:00 EST 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Inflammatory Immune Responses and Gut Microbiota Changes Following Campylobacter coli Infection of IL-10-/- Mice with Chronic Colitis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Biesemeier N,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Jul 11 00:00:00 EDT 2020
Inflammatory Immune Responses and Gut Microbiota Changes Following Campylobacter coli Infection of IL-10-/- Mice with Chronic Colitis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Biesemeier N,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Jul 11 00:00:00 EDT 2020
Assessing IL-2-Induced STAT5 Phosphorylation in Fixed, Permeabilized Foxp3+ Treg Cells by Multiparameter Flow Cytometry.
STAR protocols
Li C,Park JH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation.
Science advances
Niu L,Lou F,Sun Y,Sun L,Cai X,Liu Z,Zhou H,Wang H,Wang Z,Bai J,Yin Q,Zhang J,Chen L,Peng D,Xu Z,Gao Y,Tang S,Fan L,Wang H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation.
Science advances
Niu L,Lou F,Sun Y,Sun L,Cai X,Liu Z,Zhou H,Wang H,Wang Z,Bai J,Yin Q,Zhang J,Chen L,Peng D,Xu Z,Gao Y,Tang S,Fan L,Wang H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
FOXD3 Regulates VISTA Expression in Melanoma.
Cell reports
Rosenbaum SR,Knecht M,Mollaee M,Zhong Z,Erkes DA,McCue PA,Chervoneva I,Berger AC,Lo JA,Fisher DE,Gershenwald JE,Davies MA,Purwin TJ,Aplin AE
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy.
Nature communications
Baumann D,Hägele T,Mochayedi J,Drebant J,Vent C,Blobner S,Noll JH,Nickel I,Schumacher C,Boos SL,Daniel AS,Wendler S,Volkmar M,Strobel O,Offringa R
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Frontiers in physiology
Farini A,Villa C,Di Silvestre D,Bella P,Tripodi L,Rossi R,Sitzia C,Gatti S,Mauri P,Torrente Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Western Blot
Mon Sep 28 00:00:00 EDT 2020
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Frontiers in physiology
Farini A,Villa C,Di Silvestre D,Bella P,Tripodi L,Rossi R,Sitzia C,Gatti S,Mauri P,Torrente Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Western Blot
Mon Sep 28 00:00:00 EDT 2020
Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells.
JCI insight
Yang L,Shivakumar P,Kinder J,Way SS,Donnelly B,Mourya R,Luo Z,Bezerra JA
14-5773 was used in Immunohistochemistry to examine the liver gene expression pattern at diagnosis and found the top 5 enriched pathways are related to erythrocyte pathobiology in children who survived with the native liver beyond 2 years of age.
Thu Jun 04 00:00:00 EDT 2020
Intestinal vitamin D receptor knockout protects from oxazolone-induced colitis.
Cell death & disease
Shi Y,Liu Z,Cui X,Zhao Q,Liu T
14-5773 was used in Western Blotting to identify that intestinal vitamin D receptor knockout protected against oxazolone-induced colitis in mice by blocking Th2 cell response and reducing the function of intestinal invariant natural killer T cells.
Mon Jun 15 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma.
Aging
Liu Z,Wen J,Wu C,Hu C,Wang J,Bao Q,Wang H,Wang J,Zhou Q,Wei L,Shen Y,Zhang W
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jan 24 00:00:00 EST 2020
Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants.
Scientific reports
Wang L,Wang Z,Han R,Samanta A,Ge G,Levin LS,Levine MH,Hancock WW
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jun 09 00:00:00 EDT 2020
Immune-modulatory Properties of the Octapeptide NAP in Campylobacter jejuni Infected Mice Suffering from Acute Enterocolitis.
Microorganisms
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Giladi E,Bereswill S,Gozes I
14-5773 was used in Immunohistochemistry to provide evidence that NAP application constitutes a promising option to combat acute campylobacteriosis.
Tue May 26 00:00:00 EDT 2020
Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation.
Brain sciences
Thome R,Boehm A,Ishikawa LLW,Casella G,Munhoz J,Ciric B,Zhang GX,Rostami A
14-5773-82 was used in Flow Cytometry to analyse the CNS of experimental autoimmune encephalomyelitis mice to identify and characterize the cells that are affected by chloroquine.
Fri Jun 05 00:00:00 EDT 2020
Tumor Size Matters-Understanding Concomitant Tumor Immunity in the Context of Hypofractionated Radiotherapy with Immunotherapy.
Cancers
Nesseler JP,Lee MH,Nguyen C,Kalbasi A,Sayre JW,Romero T,Nickers P,McBride WH,Schaue D
14-5773-82 was used in Flow Cytometry to determine the dynamic contributions of different immune cell subsets to primary and abscopal tumor regression after hypofractionated radiation therapy and the impact of anti-PD-1 therapy.
Wed Mar 18 00:00:00 EDT 2020
Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Bhatia S,Longino NV,Miller NJ,Kulikauskas R,Iyer JG,Ibrani D,Blom A,Byrd DR,Parvathaneni U,Twitty CG,Campbell JS,Le MH,Gargosky S,Pierce RH,Heller R,Daud AI,Nghiem P
14-5773-82 was used in Immunohistochemistry to investigate safety, efficacy, and immunologic activity of intratumoral delivery of IL12 plasmid DNA (tavo) via in vivo electroporation (i.t.-tavo-EP) in patients with Merkel cell carcinoma (MCC), an aggressive virus-associated skin cancer.
Sat Feb 01 00:00:00 EST 2020
Microbiota composition and inflammatory immune responses upon peroral application of the commercial competitive exclusion product Aviguard® to microbiota-depleted wildtype mice.
European journal of microbiology & immunology
Heimesaat MM,Weschka D,Kløve S,Genger C,Biesemeier N,Mousavi S,Bereswill S
14-5773 was used in Immunohistochemistry to surveyed the intestinal bacterial colonization properties, potential macroscopic and microscopic inflammatory sequelae and immune responses upon peroral application of the commercial competitive exclusion product Aviguard® to wildtype mice in which the gut microbiota had been depleted by antibiotic pre-treatment.
Mon Jul 27 00:00:00 EDT 2020
The conundrum of colonization resistance against Campylobacter reloaded: The gut microbota composition in conventional mice does not prevent from Campylobacter coli infection.
European journal of microbiology & immunology
Genger C,Kløve S,Mousavi S,Bereswill S,Heimesaat MM
14-5773 was used in Immunohistochemistry to study whether this also held true for Campylobacter coli.
Fri May 01 00:00:00 EDT 2020
Transimmunization restores immune surveillance and prevents recurrence in a syngeneic mouse model of ovarian cancer.
Oncoimmunology
Alvero AB,Hanlon D,Pitruzzello M,Filler R,Robinson E,Sobolev O,Tedja R,Ventura A,Bosenberg M,Han P,Edelson RL,Mor G
14-5773 was used in Immunohistochemistry to study the results of transimmunization in high-grade serous ovarian cancer (HGSOC) mouse models.
Wed May 13 00:00:00 EDT 2020
Host deficiency in ephrin-A1 inhibits breast cancer metastasis.
F1000Research
Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Respiratory Syncytial Virus Infection Reduces Kynurenic Acid Production and Reverses Th17/Treg Balance by Modulating Indoleamine 2,3-Dioxygenase (IDO) Molecules in Plasmacytoid Dendritic Cells.
Medical science monitor : international medical journal of experimental and clinical research
Jin L,Hu Q,Hu Y,Chen Z,Liao W
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Toll-Like Receptor-4 Is Involved in Mediating Intestinal and Extra-Intestinal Inflammation in Campylobacter coli-Infected Secondary Abiotic IL-10-/- Mice.
Microorganisms
Kløve S,Genger C,Weschka D,Mousavi S,Bereswill S,Heimesaat MM
14-5773 was used in Immunohistochemistry to provide evidence that TLR4 is involved in mediating C. coli-LOS-induced immune responses in intestinal and extra-intestinal compartments during murine campylobacteriosis.
Fri Nov 27 00:00:00 EST 2020
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system.
Oncoimmunology
Klarenbeek S,Doornebal CW,Kas SM,Bonzanni N,Bhin J,Braumuller TM,van der Heijden I,Opdam M,Schouten PC,Kersten K,de Bruijn R,Zingg D,Yemelyanenko J,Wessels LFA,de Visser KE,Jonkers J
14-5773-82 was used in Immunohistochemistry to investigate treatment response and resistance to AZD8055, an inhibitor of mammalian target of rapamycin (mTOR), in the K14-cre;Cdh1Flox/Flox;Trp53Flox/Flox (KEP) mouse model of metastatic ILC.
Wed Jul 28 00:00:00 EDT 2021
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma.
Journal for immunotherapy of cancer
Shigeta K,Matsui A,Kikuchi H,Klein S,Mamessier E,Chen IX,Aoki S,Kitahara S,Inoue K,Shigeta A,Hato T,Ramjiawan RR,Staiculescu D,Zopf D,Fiebig L,Hobbs GS,Quaas A,Dima S,Popescu I,Huang P,Munn LL,Cobbold M,Goyal L,Zhu AX,Jain RK,Duda DG
14-5773-82 was used in Flow Cytometry to conclude that judicious regorafenib/anti-PD1 combination therapy can inhibit tumor growth and increase survival by normalizing tumor vasculature and increasing intratumoral CXCR3+CD8 T-cell infiltration through elevated CXCL10 expression in HCC cells.
Sun Nov 01 00:00:00 EDT 2020
Developmental Dysfunction of the Central Nervous System Lymphatics Modulates the Adaptive Neuro-Immune Response in the Perilesional Cortex in a Mouse Model of Traumatic Brain Injury.
Frontiers in immunology
Wojciechowski S,Virenque A,Vihma M,Galbardi B,Rooney EJ,Keuters MH,Antila S,Koistinaho J,Noe FM
14-5773-82 was used in Flow Cytometry to explore the role of meningeal lymphatic vessels in modulating the neuro-immune response following a traumatic brain injury.
Wed May 19 00:00:00 EDT 2021
Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction.
PloS one
Gladow N,Hollmann C,Ramos G,Frantz S,Kerkau T,Beyersdorf N,Hofmann U
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10.
Journal for immunotherapy of cancer
Bergamaschi C,Pandit H,Nagy BA,Stellas D,Jensen SM,Bear J,Cam M,Valentin A,Fox BA,Felber BK,Pavlakis GN
14-5773-82 was used in Flow Cytometry, Immunohistochemistry to show that hetIL-15 administration enhances T cell entry into tumors, increasing the success rate of immunotherapy interventions.
Fri May 01 00:00:00 EDT 2020
Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10.
Journal for immunotherapy of cancer
Bergamaschi C,Pandit H,Nagy BA,Stellas D,Jensen SM,Bear J,Cam M,Valentin A,Fox BA,Felber BK,Pavlakis GN
14-5773-82 was used in Flow Cytometry, Immunohistochemistry to show that hetIL-15 administration enhances T cell entry into tumors, increasing the success rate of immunotherapy interventions.
Fri May 01 00:00:00 EDT 2020
3'-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models.
Scientific reports
Kang LJ,Oh E,Cho C,Kwon H,Lee CG,Jeon J,Lee H,Choi S,Han SJ,Nam J,Song CU,Jung H,Kim HY,Park EJ,Choi EJ,Kim J,Eyun SI,Yang S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury.
Aging
Luo Y,Wang B,Liu J,Ma F,Luo D,Zheng Z,Lu Q,Zhou W,Zheng Y,Zhang C,Wang Q,Sha W,Chen H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.
Nature communications
Napier RJ,Lee EJ,Davey MP,Vance EE,Furtado JM,Snow PE,Samson KA,Lashley SJ,Brown BR,Horai R,Mattapallil MJ,Xu B,Callegan MC,Uebelhoer LS,Lancioni CL,Vehe RK,Binstadt BA,Smith JR,Caspi RR,Rosenzweig HL
14-5773-82 was used in Flow Cytometry to reveal a non-conventional, T cell-intrinsic function for Nod2 in suppression of Th17 immunity and experimental uveitis.
Mon Oct 26 00:00:00 EDT 2020
Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.
Frontiers in immunology
Wang A,Yang M,Liang R,Zhu F,Zhu F,Liu X,Han Y,Lin R,Wang X,Li D,Li H,Yuan X,Zhao H,Li B
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Apr 05 00:00:00 EDT 2021
Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.
Frontiers in immunology
Wang A,Yang M,Liang R,Zhu F,Zhu F,Liu X,Han Y,Lin R,Wang X,Li D,Li H,Yuan X,Zhao H,Li B
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Apr 05 00:00:00 EDT 2021
In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.
Journal for immunotherapy of cancer
Clark PA,Sriramaneni RN,Jin WJ,Jagodinsky JC,Bates AM,Jaquish AA,Anderson BR,Le T,Lubin JA,Chakravarty I,Arthur IS,Heinze CM,Guy EI,Kler J,Klar KA,Carlson PM,Kim KM,Kuo JS,Morris ZS
14-5773 was used in Immunohistochemistry to test whether in situ vaccination inhibits the development of brain metastases in a murine melanoma model.
Wed Jul 01 00:00:00 EDT 2020
Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice.
Journal of translational autoimmunity
Jackson-Thompson BM,Torrero M,Mitre BK,Long J,Packiam M,Mitre E
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
Biomedicines
Ebelt ND,Zuniga E,Marzagalli M,Zamloot V,Blazar BR,Salgia R,Manuel ER
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma.
Cell
Wolf Y,Bartok O,Patkar S,Eli GB,Cohen S,Litchfield K,Levy R,Jiménez-Sánchez A,Trabish S,Lee JS,Karathia H,Barnea E,Day CP,Cinnamon E,Stein I,Solomon A,Bitton L,Pérez-Guijarro E,Dubovik T,Shen-Orr SS,Miller ML,Merlino G,Levin Y,Pikarsky E,Eisenbach L,Admon A,Swanton C,Ruppin E,Samuels Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Sep 19 00:00:00 EDT 2019
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.
Cell research
Zhang Y,Du X,Liu M,Tang F,Zhang P,Ai C,Fields JK,Sundberg EJ,Latinovic OS,Devenport M,Zheng P,Liu Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression.
Cancer cell
Su W,Han HH,Wang Y,Zhang B,Zhou B,Cheng Y,Rumandla A,Gurrapu S,Chakraborty G,Su J,Yang G,Liang X,Wang G,Rosen N,Scher HI,Ouerfelli O,Giancotti FG
14-5773 was used in Immunohistochemistry to reveal that PRC1 coordinates stemness with immune evasion and neoangiogenesis and point to the potential clinical utility of targeting PRC1 in DNPC.
Mon Aug 12 00:00:00 EDT 2019
Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense.
Cell stem cell
Chen M,Reed RR,Lane AP
14-5773 was used in Flow cytometry/Cell sorting to establish a mechanism whereby chronic rhinosinusitis inflammation causes a functional switch of neuroepithelial stem cells from regeneration to immune defense.
Thu Oct 03 00:00:00 EDT 2019
Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
The Journal of clinical investigation
Pai CS,Simons DM,Lu X,Evans M,Wei J,Wang YH,Chen M,Huang J,Park C,Chang A,Wang J,Westmoreland S,Beam C,Banach D,Bowley D,Dong F,Seagal J,Ritacco W,Richardson PL,Mitra S,Lynch G,Bousquet P,Mankovich J,Kingsbury G,Fong L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Wed Jan 02 00:00:00 EST 2019
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.
The Journal of experimental medicine
Melo-Gonzalez F,Kammoun H,Evren E,Dutton EE,Papadopoulou M,Bradford BM,Tanes C,Fardus-Reid F,Swann JR,Bittinger K,Mabbott NA,Vallance BA,Willinger T,Withers DR,Hepworth MR
14-5773-82 was used in Flow Cytometry to study the mechanisms that modulate the magnitude and quality of T cell-dependent IgA responses.
Mon Apr 01 00:00:00 EDT 2019
ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity.
Molecular therapy : the journal of the American Society of Gene Therapy
Soldevilla MM,Villanueva H,Meraviglia-Crivelli D,Menon AP,Ruiz M,Cebollero J,Villalba M,Moreno B,Lozano T,Llopiz D,Pejenaute Á,Sarobe P,Pastor F
14-5773-82 was used in Immunohistochemistry (Paraffin) to to describe an ICOS agonistic aptamer that potentiates T cell activation and induces stronger antitumor responses when locally injected at the tumor site in combination with anti-CTLA-4 antibody in different tumor models.
Wed Nov 06 00:00:00 EST 2019
TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.
Proceedings of the National Academy of Sciences of the United States of America
Sharma N,Vacher J,Allison JP
14-5773-82 was used in Flow Cytometry to show that this mechanism could be harnessed to modulate the clinical outcome of anti-CTLA-4 antibodies and possibly other antibody-based immunotherapies.
Tue May 21 00:00:00 EDT 2019
Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression.
Oncogene
Kim SJ,Garcia-Recio S,Creighton CJ,Perou CM,Rosen JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Thu Aug 01 00:00:00 EDT 2019
Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression.
Oncogene
Kim SJ,Garcia-Recio S,Creighton CJ,Perou CM,Rosen JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunocytochemistry
Thu Aug 01 00:00:00 EDT 2019
BATF3-dependent dendritic cells drive both effector and regulatory T-cell responses in bacterially infected tissues.
PLoS pathogens
Arnold IC,Zhang X,Artola-Boran M,Fallegger A,Sander P,Johansen P,Müller A
14-5773 was used in Flow cytometry/Cell sorting to study the role of BATF3-dependent DCs in the recruitment of CXCR3+ effector and regulatory T-cells to target tissues and in their local expansion.
Sat Jun 01 00:00:00 EDT 2019
Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice.
American journal of physiology. Lung cellular and molecular physiology
Shrestha AK,Bettini ML,Menon RT,Gopal VYN,Huang S,Edwards DP,Pammi M,Barrios R,Shivanna B
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells.
Immune network
Kim JE,Sharma A,Sharma G,Lee SY,Shin HS,Rudra D,Im SH
14-5773-82 was used in Flow Cytometry to demonstrate that LP340, a bacterium derived from food, prevents systemic inflammation through the induction of IL-10 producing Tr1 cells.
Sun Dec 01 00:00:00 EST 2019
CD55 Is Essential for CD103+ Dendritic Cell Tolerogenic Responses that Protect against Autoimmunity.
The American journal of pathology
Strainic MG,Liu J,An F,Bailey E,Esposito A,Hamann J,Heeger PS,Medof ME
14-5773 was used in Immuno-assay to study the importance of DAF in enabling processes that program tolerance in the gut and the eye.
Mon Jul 01 00:00:00 EDT 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
A Skin Rejection Grading System for Vascularized Composite Allotransplantation in a Preclinical Large Animal Model.
Transplantation
Etra JW,Grzelak MJ,Fidder SAJ,Kolegraff K,Bonawitz S,Shores J,Oh B,Cooney DS,Beck SE,Brandacher G
14-5773 was used in Immunohistochemistry to provide a standardized system for more accurate comparison of rejection in preclinical swine VCA models.
Mon Jul 01 00:00:00 EDT 2019
T Lymphocytes Attenuate Dermal Scarring by Regulating Inflammation, Neovascularization, and Extracellular Matrix Remodeling.
Advances in wound care
Wang X,Balaji S,Steen EH,Li H,Rae MM,Blum AJ,Miao Q,Butte MJ,Bollyky PL,Keswani SG
14-5773 was used in Immunohistochemistry to implicate adaptive immunity in the regulation of scarring phenotypes.
Fri Nov 01 00:00:00 EDT 2019
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials.
Journal of mammary gland biology and neoplasia
Pénzváltó Z,Chen JQ,Tepper CG,Davis RR,Silvestrini MT,Umeh-Garcia M,Sweeney C,Borowsky AD
14-5773-82 was used in Immunohistochemistry to show that the NDLUCD cells have, so far, remained genetically and phenotypically stable over many generations, with consistent and reproducible results in immune intact preclinical cohorts.
Sat Jun 01 00:00:00 EDT 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1.
Journal for immunotherapy of cancer
Thomas S,Kuncheria L,Roulstone V,Kyula JN,Mansfield D,Bommareddy PK,Smith H,Kaufman HL,Harrington KJ,Coffin RS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Sat Aug 10 00:00:00 EDT 2019
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.
Nature communications
Eissmann MF,Dijkstra C,Jarnicki A,Phesse T,Brunnberg J,Poh AR,Etemadi N,Tsantikos E,Thiem S,Huntington ND,Hibbs ML,Boussioutas A,Grimbaldeston MA,Buchert M,O'Donoghue RJJ,Masson F,Ernst M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Jun 21 00:00:00 EDT 2019
Mesenchymal Stem Cells Extract (MSCsE)-Based Therapy Alleviates Xerostomia and Keratoconjunctivitis Sicca in Sjogren's Syndrome-Like Disease.
International journal of molecular sciences
Abughanam G,Elkashty OA,Liu Y,Bakkar MO,Tran SD
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Sep 25 00:00:00 EDT 2019
The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models.
Nature communications
Martínez-Vélez N,Garcia-Moure M,Marigil M,González-Huarriz M,Puigdelloses M,Gallego Pérez-Larraya J,Zalacaín M,Marrodán L,Varela-Guruceaga M,Laspidea V,Aristu JJ,Ramos LI,Tejada-Solís S,Díez-Valle R,Jones C,Mackay A,Martínez-Climent JA,García-Barchino MJ,Raabe E,Monje M,Becher OJ,Junier MP,El-Habr EA,Chneiweiss H,Aldave G,Jiang H,Fueyo J,Patiño-García A,Gomez-Manzano C,Alonso MM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue May 28 00:00:00 EDT 2019
The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models.
Nature communications
Martínez-Vélez N,Garcia-Moure M,Marigil M,González-Huarriz M,Puigdelloses M,Gallego Pérez-Larraya J,Zalacaín M,Marrodán L,Varela-Guruceaga M,Laspidea V,Aristu JJ,Ramos LI,Tejada-Solís S,Díez-Valle R,Jones C,Mackay A,Martínez-Climent JA,García-Barchino MJ,Raabe E,Monje M,Becher OJ,Junier MP,El-Habr EA,Chneiweiss H,Aldave G,Jiang H,Fueyo J,Patiño-García A,Gomez-Manzano C,Alonso MM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue May 28 00:00:00 EDT 2019
An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma.
Cell reports
Carper MB,Troutman S,Wagner BL,Byrd KM,Selitsky SR,Parag-Sharma K,Henry EC,Li W,Parker JS,Montgomery SA,Cleveland JL,Williams SE,Kissil JL,Hayes DN,Amelio AL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Tue Nov 05 00:00:00 EST 2019
Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model.
Frontiers in immunology
Mousavi S,Lobo de Sá FD,Schulzke JD,Bücker R,Bereswill S,Heimesaat MM
14-5773 was used in Immunohistochemistry to show that synthetic 25-OH-cholecalciferol injected perorally, acts as an anti-inflammatory during acute campylobacteriosis.
Mon Nov 09 00:00:00 EST 2020
IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.
JCI insight
Liu Q,Dwyer GK,Zhao Y,Li H,Mathews LR,Chakka AB,Chandran UR,Demetris JA,Alcorn JF,Robinson KM,Ortiz LA,Pitt BR,Thomson AW,Fan MH,Billiar TR,Turnquist HR
14-5773 was used in Flow cytometry/Cell sorting to study the anti-inflammatory actions of interleukins and effects on shaping myeloid compartment post lung injury.
Thu Mar 21 00:00:00 EDT 2019
Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis.
EBioMedicine
Yamada T,Hino S,Iijima H,Genda T,Aoki R,Nagata R,Han KH,Hirota M,Kinashi Y,Oguchi H,Suda W,Furusawa Y,Fujimura Y,Kunisawa J,Hattori M,Fukushima M,Morita T,Hase K
14-5773 was used in Flow cytometry/Cell sorting to propose that abnormal mucin utilisation may lead to reduced n-butyrate production in ulcerative colitis patients and that mucin o-glycans can facilitate symbiosynthesis of n-butyrate by gut microbiota.
Tue Oct 01 00:00:00 EDT 2019
Generation of Foxp3+CD25- Regulatory T-Cell Precursors Requires c-Rel and IκBNS.
Frontiers in immunology
Schuster M,Plaza-Sirvent C,Visekruna A,Huehn J,Schmitz I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jun 04 00:00:00 EDT 2020
Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease.
Frontiers in immunology
Strattan E,Palaniyandi S,Kumari R,Du J,Hakim N,Huang T,Kesler MV,Jennings CD,Sturgill JL,Hildebrandt GC
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Nov 17 00:00:00 EST 2020
Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.
Cell reports
Fleskens V,Minutti CM,Wu X,Wei P,Pals CEGM,McCrae J,Hemmers S,Groenewold V,Vos HJ,Rudensky A,Pan F,Li H,Zaiss DM,Coffer PJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunoprecipitation
Tue Mar 26 00:00:00 EDT 2019
miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2.
JCI insight
Do DC,Mu J,Ke X,Sachdeva K,Qin Z,Wan M,Ishmael FT,Gao P
14-5773 was used in Flow cytometry/Cell sorting to identify how miR-511-3p regulates allergic inflammation and macrophage polarisation by inhibiting Ccl2 and its downstream Ccr2/RhoA downstream axis.
Thu Oct 17 00:00:00 EDT 2019
Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice.
Nature microbiology
Wotzka SY,Kreuzer M,Maier L,Arnoldini M,Nguyen BD,Brachmann AO,Berthold DL,Zünd M,Hausmann A,Bakkeren E,Hoces D,Gül E,Beutler M,Dolowschiak T,Zimmermann M,Fuhrer T,Moor K,Sauer U,Typas A,Piel J,Diard M,Macpherson AJ,Stecher B,Sunagawa S,Slack E,Hardt WD
14-5773-82 was used in Flow Cytometry to determine whether food composition shifts enhance susceptibility to infection as diet affects microbiota composition.
Sun Dec 01 00:00:00 EST 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells.
Cancers
Liu Y,Bao C,Wang L,Han R,Beier UH,Akimova T,Cole PA,Dent SYR,Hancock WW
14-5773 was used in Immunocytochemistry to show that two prototypical GNAT family members, GCN5 (general control nonrepressed-protein 5, lysine acetyltransferase (KAT)2a) and p300/CBP-associated factor (p300/CBP-associated factor (PCAF), Kat2b) contribute to Treg functions through partially distinct and partially overlapping mechanisms.
Thu Apr 18 00:00:00 EDT 2019
Loss of TET2 and TET3 in regulatory T cells unleashes effector function.
Nature communications
Yue X,Lio CJ,Samaniego-Castruita D,Li X,Rao A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue May 14 00:00:00 EDT 2019
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
Nature communications
Kusano T,Ehirchiou D,Matsumura T,Chobaz V,Nasi S,Castelblanco M,So A,Lavanchy C,Acha-Orbea H,Nishino T,Okamoto K,Busso N
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Oct 28 00:00:00 EDT 2019
Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis.
Scientific reports
Brichacek AL,Benkovic SA,Chakraborty S,Nwafor DC,Wang W,Jun S,Dakhlallah D,Geldenhuys WJ,Pinkerton AB,Millán JL,Brown CM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice.
Oncoimmunology
Lévesque S,Le Naour J,Pietrocola F,Paillet J,Kremer M,Castoldi F,Baracco EE,Wang Y,Vacchelli E,Stoll G,Jolly A,De La Grange P,Zitvogel L,Kroemer G,Pol JG
14-5773-82 was used in In Vivo to point to the possibility of synergistic interactions among distinct classes of anticancer agents.
Sat Oct 14 00:00:00 EDT 2023
90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin's Lymphoma.
Communications biology
Hernandez R,Walker KL,Grudzinski JJ,Aluicio-Sarduy E,Patel R,Zahm CD,Pinchuk AN,Massey CF,Bitton AN,Brown RJ,Sondel PM,Morris ZS,Engle JW,Capitini CM,Weichert JP
14-5773 was used in Immunohistochemistry to study the role of the adaptive immune system in potentiating a durable anti-tumour response to targeted radionuclide therapy.
Wed Apr 22 00:00:00 EDT 2020
A20 as an immune tolerance factor can determine islet transplant outcomes.
JCI insight
Zammit NW,Walters SN,Seeberger KL,O'Connell PJ,Korbutt GS,Grey ST
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
A20 as an immune tolerance factor can determine islet transplant outcomes.
JCI insight
Zammit NW,Walters SN,Seeberger KL,O'Connell PJ,Korbutt GS,Grey ST
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation.
JCI insight
Kono M,Maeda K,Stocton-Gavanescu I,Pan W,Umeda M,Katsuyama E,Burbano C,Orite SYK,Vukelic M,Tsokos MG,Yoshida N,Tsokos GC
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that CaMK4 binds to PKM2 and promotes its activity, which is requisite for Th1 and Th17 differentiation.
Thu Jun 20 00:00:00 EDT 2019
Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.
Oncoimmunology
Salerno F,Guislain A,Freen-Van Heeren JJ,Nicolet BP,Young HA,Wolkers MC
14-5773 was used in Flow cytometry/Cell sorting to conclude that post-transcriptional mechanisms could be modulated to potentiate effective T cell therapies in cancer.
Tue Jan 12 00:00:00 EST 2021
Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival.
Scientific reports
Uehara M,Li X,Sheikhi A,Zandi N,Walker B,Saleh B,Banouni N,Jiang L,Ordikhani F,Dai L,Yonar M,Vohra I,Kasinath V,Orgill DP,Khademhosseini A,Annabi N,Abdi R
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Apr 25 00:00:00 EDT 2019
Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models.
Acta neuropathologica communications
Martinez-Velez N,Marigil M,García-Moure M,Gonzalez-Huarriz M,Aristu JJ,Ramos-García LI,Tejada S,Díez-Valle R,Patiño-García A,Becher OJ,Gomez-Manzano C,Fueyo J,Alonso MM
14-5773-82 was used in Immunohistochemistry to evaluate the feasibility, safety and therapeutic efficacy of Delta-24-RGD, a genetically engineered tumor-selective adenovirus, in combination with radiotherapy in pediatric high grade glioma and diffuse intrinsic pontine glioma models.
Mon Apr 29 00:00:00 EDT 2019
Multidrug-Resistant Pseudomonas aeruginosa Accelerate Intestinal, Extra-Intestinal, and Systemic Inflammatory Responses in Human Microbiota-Associated Mice With Subacute Ileitis.
Frontiers in immunology
Heimesaat MM,Escher U,Grunau A,Kühl AA,Bereswill S
14-5773 was used in Immunohistochemistry to study the factors facilitating gastrointestinal Pseudomonas aeruginosa-acquisition by the vertebrate host and subsequently induced inflammatory sequelae.
Fri Dec 20 00:00:00 EST 2019
Hepatic Stellate Cells Enhance Liver Cancer Progression by Inducing Myeloid-Derived Suppressor Cells through Interleukin-6 Signaling.
International journal of molecular sciences
Hsieh CC,Hung CH,Chiang M,Tsai YC,He JT
14-5773-82 was used in Flow Cytometry to provide in vitro and in vivo evidences that HSCs induce the generation of MDSCs to promote hepatocellular carcinoma (HCC) progression through interleukin (IL)-6 secretion.
Sun Oct 13 00:00:00 EDT 2019
Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Cell reports
Fu Z,Ye J,Dean JW,Bostick JW,Weinberg SE,Xiong L,Oliff KN,Chen ZE,Avram D,Chandel NS,Zhou L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability.
Frontiers in immunology
Ronin E,Lubrano di Ricco M,Vallion R,Divoux J,Kwon HK,Grégoire S,Collares D,Rouers A,Baud V,Benoist C,Salomon BL
14-5773-82 was used in Flow Cytometry to show that RelA, a key member of the NF-κB complex, is critical for Treg biology as it promotes both the generation of their effector phenotype and the maintenance of their identity.
Thu Oct 29 00:00:00 EDT 2020
CXCR5-negative natural killer cells ameliorate experimental autoimmune myasthenia gravis by suppressing follicular helper T cells.
Journal of neuroinflammation
Yang CL,Zhang P,Liu RT,Zhang N,Zhang M,Li H,Du T,Li XL,Dou YC,Duan RS
14-5773-82 was used in Flow Cytometry to investigate the function of NK cells in experimental autoimmune myasthenia gravis in vivo.
Sun Dec 29 00:00:00 EST 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Immunity
Mollaoglu G,Jones A,Wait SJ,Mukhopadhyay A,Jeong S,Arya R,Camolotto SA,Mosbruger TL,Stubben CJ,Conley CJ,Bhutkar A,Vahrenkamp JM,Berrett KC,Cessna MH,Lane TE,Witt BL,Salama ME,Gertz J,Jones KB,Snyder EL,Oliver TG
14-5773 was used in Immunohistochemistry to identify that SOX2 and NKX2-1 lineage-defining transcription factors regulate tumour immune microenvironment and determine lung cancer cell fate.
Tue Oct 16 00:00:00 EDT 2018
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell
Zappasodi R,Budhu S,Hellmann MD,Postow MA,Senbabaoglu Y,Manne S,Gasmi B,Liu C,Zhong H,Li Y,Huang AC,Hirschhorn-Cymerman D,Panageas KS,Wherry EJ,Merghoub T,Wolchok JD
14-5773-82 was used in Flow Cytometry to provide evidence that mouse and human circulating and intra-tumor 4PD1hi inhibit T cell functions in a PD-1/PD-L1 dependent fashion and resemble follicular helper T cell (TFH)-like cells.
Mon Jun 11 00:00:00 EDT 2018
PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.
The Journal of clinical investigation
Kraakman MJ,Liu Q,Postigo-Fernandez J,Ji R,Kon N,Larrea D,Namwanje M,Fan L,Chan M,Area-Gomez E,Fu W,Creusot RJ,Qiang L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response.
The Journal of clinical investigation
Ubil E,Caskey L,Holtzhausen A,Hunter D,Story C,Earp HS
14-5773 was used in Immunohistochemistry to demonstrate that tumour-secreted protein S, a Mer/Tyro3 ligand, decreases macrophage M1 cytokine expression in vitro and in vivo.
Fri Jun 01 00:00:00 EDT 2018
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.
The Journal of experimental medicine
Lynch JP,Werder RB,Loh Z,Sikder MAA,Curren B,Zhang V,Rogers MJ,Lane K,Simpson J,Mazzone SB,Spann K,Hayball J,Diener K,Everard ML,Blyth CC,Forstner C,Dennis PG,Murtaza N,Morrison M,Ó Cuív P,Zhang P,Haque A,Hill GR,Sly PD,Upham JW,Phipps S
14-5773 was used in Immunohistochemistry on paraffin embedded tissues to identify that transient plasmacytoid dendritic cell depletion during primary Pneumovirus infection alone predisposes to severe bronchiolitis in early life and subsequent asthma in later life after reinfection.
Mon Feb 05 00:00:00 EST 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-5773 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 EST 2018
The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.
The Journal of experimental medicine
Balbinot C,Armant O,Elarouci N,Marisa L,Martin E,De Clara E,Onea A,Deschamps J,Beck F,Freund JN,Duluc I
14-5773 was used in Immunohistochemistry-immunofluorescence to study the mechanisms by which the Cdx25 homeobox gene suppresses intestinal tumourigenesis.
Mon Mar 05 00:00:00 EST 2018
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
The Journal of experimental medicine
Delpoux A,Michelini RH,Verma S,Lai CY,Omilusik KD,Utzschneider DT,Redwood AJ,Goldrath AW,Benedict CA,Hedrick SM
14-5773 was used in Flow cytometry/Cell sorting to show that FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells.
Mon Feb 05 00:00:00 EST 2018
Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells.
The Journal of experimental medicine
Seki A,Rutz S
14-5773 was used in Flow cytometry/Cell sorting to develop an optimised approach for Cas9/RNP transfection of primary mouse and human T cells without TCR stimulation, that results in near complete loss of target gene expression at the population level.
Mon Mar 05 00:00:00 EST 2018
IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN.
Journal of the American Society of Nephrology : JASN
Diefenhardt P,Nosko A,Kluger MA,Richter JV,Wegscheid C,Kobayashi Y,Tiegs G,Huber S,Flavell RA,Stahl RAK,Steinmetz OM
14-5773 was used in Immunohistochemistry to identify and characterize mechanisms responsible for generation, activation, and functional differentiation of Tregs.
Sun Jul 01 00:00:00 EDT 2018
Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Marciscano AE,Ghasemzadeh A,Nirschl TR,Theodros D,Kochel CM,Francica BJ,Muroyama Y,Anders RA,Sharabi AB,Velarde E,Mao W,Chaudhary KR,Chaimowitz MG,Wong J,Selby MJ,Thudium KB,Korman AJ,Ulmert D,Thorek DLJ,DeWeese TL,Drake CG
14-5773 was used in Flow cytometry/Cell sorting to study the effects of elective novel irradiation on the adaptive immune system and if this increases its antitumour effects.
Mon Oct 15 00:00:00 EDT 2018
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy
Ricca JM,Oseledchyk A,Walther T,Liu C,Mangarin L,Merghoub T,Wolchok JD,Zamarin D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Apr 04 00:00:00 EDT 2018
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB
14-5773 was used in Immunohistochemistry to show that p38/MAPKAP Kinase 2 activity in the myeloid compartment promotes tumour progression by supporting tumour neoangiogenesis in vivo.
Tue May 01 00:00:00 EDT 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.
PLoS biology
Mensurado S,Rei M,Lança T,Ioannou M,Gonçalves-Sousa N,Kubo H,Malissen M,Papayannopoulos V,Serre K,Silva-Santos B
14-5773 was used in Flow cytometry/Cell sorting to study the role of tumour-associated neutrophils in the regulation of γδ17 T-cell responses in the tumour microenvironment.
Tue May 01 00:00:00 EDT 2018
Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.
British journal of pharmacology
Lu Y,Kim NM,Jiang YW,Zhang H,Zheng D,Zhu FX,Liang R,Li B,Xu HX
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Apr 01 00:00:00 EDT 2018
Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.
British journal of pharmacology
Lu Y,Kim NM,Jiang YW,Zhang H,Zheng D,Zhu FX,Liang R,Li B,Xu HX
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sun Apr 01 00:00:00 EDT 2018
Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
LaMothe RA,Kolte PN,Vo T,Ferrari JD,Gelsinger TC,Wong J,Chan VT,Ahmed S,Srinivasan A,Deitemeyer P,Maldonado RA,Kishimoto TK
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Mar 21 00:00:00 EDT 2019
CD4+ T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development.
Frontiers in immunology
Cobbold SP,Adams E,Howie D,Waldmann H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jan 31 00:00:00 EST 2022
Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions.
Mucosal immunology
Varanasi SK,Rajasagi NK,Jaggi U,Rouse BT
14-5773 was used in Flow cytometry/Cell sorting to investigate IL-18's mechanisms to control of inflammatory lesions in the cornea caused by the herpes infection.
Thu Nov 01 00:00:00 EDT 2018
Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes.
Immunology
Yap JY,Wirasinha RC,Chan A,Howard DR,Goodnow CC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tsutsui M,Hirase R,Miyamura S,Nagayasu K,Nakagawa T,Mori Y,Shirakawa H,Kaneko S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Sep 26 00:00:00 EDT 2018
Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells.
Journal of immunology (Baltimore, Md. : 1950)
Ferdinand JR,Richard AC,Meylan F,Al-Shamkhani A,Siegel RM
14-5773 was used in Flow cytometry/Cell sorting to suggest differential roles for membrane and soluble TL1A on adaptive and innate immune cells and have implications for the consequences of blocking these two forms of TL1A.
Thu Feb 15 00:00:00 EST 2018
Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Sprouse ML,Shevchenko I,Scavuzzo MA,Joseph F,Lee T,Blum S,Borowiak M,Bettini ML,Bettini M
14-5773 was used in Flow cytometry/Cell sorting to reveal a role for both high- and low-affinity Tregs in the control of autoimmunity.
Thu Feb 01 00:00:00 EST 2018
FOXP3 expression is modulated by TGF‑β1/NOTCH1 pathway in human melanoma.
International journal of molecular medicine
Skarmoutsou E,Bevelacqua V,D' Amico F,Russo A,Spandidos DA,Scalisi A,Malaponte G,Guarneri C
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Western Blot
Sun Jul 01 00:00:00 EDT 2018
Immunologic and gene expression profiles of spontaneous canine oligodendrogliomas.
Journal of neuro-oncology
Filley A,Henriquez M,Bhowmik T,Tewari BN,Rao X,Wan J,Miller MA,Liu Y,Bentley RT,Dey M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in In Situ Hybridization (ISH)
Tue May 01 00:00:00 EDT 2018
CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro.
Journal of immunology research
Pilat N,Mahr B,Gattringer M,Baranyi U,Wekerle T
14-5773 was used in Flow cytometry/Cell sorting to investigate the compatibility of CTLA4lg with regulatory T cells by evaluating direct effects of CTLA4lg on murine Treg generation and function in vitro.
Mon Nov 05 00:00:00 EST 2018
Modulated electro-hyperthermia induced loco-regional and systemic tumor destruction in colorectal cancer allografts.
Journal of Cancer
Vancsik T,Kovago C,Kiss E,Papp E,Forika G,Benyo Z,Meggyeshazi N,Krenacs T
14-5773 was used in Immunohistochemistry to test the modulated electro-hyperthermia induced stress and immune responses, in C26 colorectal cancer allografts.
Thu Oct 01 00:00:00 EDT 2020
PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani.
Infection and immunity
Habib S,El Andaloussi A,Elmasry K,Handoussa A,Azab M,Elsawey A,Al-Hendy A,Ismail N
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Anti PD-1 treatment increases [18F]FDG uptake by cancer cells in a mouse B16F10 melanoma model.
EJNMMI research
Tomita M,Yasui H,Higashikawa K,Nakajima K,Takakura H,Shiga T,Kuge Y,Ogawa M
14-5773-82 was used in Flow Cytometry to show that anti PD-1 therapy increases glucose metabolism in cancer cells.
Thu Aug 16 00:00:00 EDT 2018
Immunological effects of a low-dose cytarabine, aclarubicin and granulocyte-colony stimulating factor priming regimen on a mouse leukemia model.
Oncology letters
Chen J,Yang N,Liu H,Yao H,Wang J,Yang Y,Zhang W
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Assessment of tumor growth factor-β1 neutralizing antibody in the treatment of allergic rhinitis and asthma.
Experimental and therapeutic medicine
Wei Y,Zhang Z,Wang F,Zhou S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells.
Experimental and therapeutic medicine
Liu Y,Sun L,Chen W,Chuai J,Shang Y,Zhang D,Fu B,Tian H,Jiang S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer.
Journal for immunotherapy of cancer
Pennock ND,Martinson HA,Guo Q,Betts CB,Jindal S,Tsujikawa T,Coussens LM,Borges VF,Schedin P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Oct 01 00:00:00 EDT 2018
Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer.
Journal for immunotherapy of cancer
Pennock ND,Martinson HA,Guo Q,Betts CB,Jindal S,Tsujikawa T,Coussens LM,Borges VF,Schedin P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Oct 01 00:00:00 EDT 2018
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.
Nature communications
Wunderlich CM,Ackermann PJ,Ostermann AL,Adams-Quack P,Vogt MC,Tran ML,Nikolajev A,Waisman A,Garbers C,Theurich S,Mauer J,Hövelmeyer N,Wunderlich FT
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Apr 25 00:00:00 EDT 2018
Peroral Low-Dose Toxoplasma gondii Infection of Human Microbiota-Associated Mice - A Subacute Ileitis Model to Unravel Pathogen-Host Interactions.
European journal of microbiology & immunology
Heimesaat MM,Escher U,Grunau A,Fiebiger U,Bereswill S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jun 25 00:00:00 EDT 2018
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.
Nature communications
Chen D,Xie J,Fiskesund R,Dong W,Liang X,Lv J,Jin X,Liu J,Mo S,Zhang T,Cheng F,Zhou Y,Zhang H,Tang K,Ma J,Liu Y,Huang B
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Feb 28 00:00:00 EST 2018
Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells.
Nature communications
Lopes N,Charaix J,Cédile O,Sergé A,Irla M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells.
Cell reports
Ogawa C,Bankoti R,Nguyen T,Hassanzadeh-Kiabi N,Nadeau S,Porritt RA,Couse M,Fan X,Dhall D,Eberl G,Ohnmacht C,Martins GA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Oct 02 00:00:00 EDT 2018
Immunomodulatory role of Keratin 76 in oral and gastric cancer.
Nature communications
Sequeira I,Neves JF,Carrero D,Peng Q,Palasz N,Liakath-Ali K,Lord GM,Morgan PR,Lombardi G,Watt FM
14-5773 was used in Flow cytometry/Cell sorting to demonstrate keratin 76 in epithelial cells regulate carcinocgenesis via communication with cells of the immune system.
Fri Aug 24 00:00:00 EDT 2018
Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice.
Scientific reports
Uhde AK,Ciurkiewicz M,Herder V,Khan MA,Hensel N,Claus P,Beckstette M,Teich R,Floess S,Baumgärtner W,Jung K,Huehn J,Beineke A
14-5773 was used in Immunohistochemistry to study IL-10R signaling following virus-induced polioencephalitis in SJL mice.
Tue Apr 17 00:00:00 EDT 2018
Respiratory Bordetella bronchiseptica Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice.
International journal of molecular sciences
Jeron A,Boehme JD,Volckmar J,Gereke M,Yevsa T,Geffers R,Guzmán CA,Schreiber J,Stegemann-Koniszewski S,Bruder D
14-5773 was used in Flow cytometry/Cell sorting to study the effects of respiratory bacterial carriage on the immune system and its implications for secondary responses.
Sat Sep 01 00:00:00 EDT 2018
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.
Nature communications
Fiore A,Ugel S,De Sanctis F,Sandri S,Fracasso G,Trovato R,Sartoris S,Solito S,Mandruzzato S,Vascotto F,Hippen KL,Mondanelli G,Grohmann U,Piro G,Carbone C,Melisi D,Lawlor RT,Scarpa A,Lamolinara A,Iezzi M,Fassan M,Bicciato S,Blazar BR,Sahin U,Murray PJ,Bronte V
14-5773 was used in Immunohistochemistry to demonstrate that low-dose cytotoxic chemotherapy agents cause apoptosis linked to c-FLIP down-regulation selectively in monocytes.
Wed Dec 05 00:00:00 EST 2018
IL-23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice.
Journal of the American Heart Association
Engelbertsen D,Depuydt MAC,Verwilligen RAF,Rattik S,Levinsohn E,Edsfeldt A,Kuperwaser F,Jarolim P,Lichtman AH
14-5773 was used in Flow cytometry/Cell sorting to investigate the presence of IL-23R expressing cells in the atherosclerotic aorta and it's effect on development when deficient.
Wed Apr 04 00:00:00 EDT 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Jan 31 00:00:00 EST 2018
Factors Produced by Macrophages Eliminating Apoptotic Cells Demonstrate Pro-Resolutive Properties and Terminate Ongoing Inflammation.
Frontiers in immunology
Bonnefoy F,Gauthier T,Vallion R,Martin-Rodriguez O,Missey A,Daoui A,Valmary-Degano S,Saas P,Couturier M,Perruche S
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that the factors produced by macrophages eliminating apoptotic cells were sufficient to reboot the resolution of inflammation in vivo, and thus definitively terminated ongoing chronic inflammation.
Thu Oct 03 00:00:00 EDT 2019
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
An orally-active adiponectin receptor agonist mitigates cutaneous fibrosis, inflammation and microvascular pathology in a murine model of systemic sclerosis.
Scientific reports
Yamashita T,Lakota K,Taniguchi T,Yoshizaki A,Sato S,Hong W,Zhou X,Sodin-Semrl S,Fang F,Asano Y,Varga J
14-5773 was used in Flow cytometry/Cell sorting to study the effectiveness of AdipoRon, an orally active adiponectin receptor agonist, in treatment of systemic sclerosis in mice.
Tue Aug 07 00:00:00 EDT 2018
Accumulation of IL-17+ Vγ6+ γδ T cells in pregnant mice is not associated with spontaneous abortion.
Clinical & translational immunology
Polese B,Gridelet V,Perrier d'Hauterive S,Renard C,Munaut C,Martens H,Vermijlen D,King IL,Jacobs N,Geenen V
14-5773 was used in Flow cytometry/Cell sorting to define the kinetics and cellular source of IL-17A in the uterus during healthy and abortion-prone murine pregnancy.
Wed Sep 30 00:00:00 EDT 2020
CCL3 Promotes Germinal Center B Cells Sampling by Follicular Regulatory T Cells in Murine Lymph Nodes.
Frontiers in immunology
Benet ZL,Marthi M,Ke F,Wu R,Turner JS,Gabayre JB,Ivanitskiy MI,Sethi SS,Grigorova IL
14-5773 was used in Flow cytometry/Cell sorting to suggest that CCL3 facilitates direct interactions of foreign antigen-specific GC B cells and their negative regulation with Tfr cells in vivo.
Mon Sep 30 00:00:00 EDT 2019
Inflammation-induced Id2 promotes plasticity in regulatory T cells.
Nature communications
Hwang SM,Sharma G,Verma R,Byun S,Rudra D,Im SH
14-5773 was used in Flow cytometry/Cell sorting to show that pro-inflammatory cytokines enhance the expression of transcription regulator Id2, which mediates cellular plasticity of Treg into ex-Foxp3 TH17 cells.
Fri Nov 09 00:00:00 EST 2018
Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury.
Journal of neuroinflammation
Alizadeh A,Santhosh KT,Kataria H,Gounni AS,Karimi-Abdolrezaee S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Feb 21 00:00:00 EST 2018
High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice.
Scientific reports
Dar HY,Singh A,Shukla P,Anupam R,Mondal RK,Mishra PK,Srivastava RK
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Feb 06 00:00:00 EST 2018
Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice.
Scientific reports
Quan S,Principe DR,Dean AE,Park SH,Grippo PJ,Gius D,Horikoshi N
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Nov 07 00:00:00 EST 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells.
Nature communications
Chen S,Fang L,Guo W,Zhou Y,Yu G,Li W,Dong K,Liu J,Luo Y,Wang B,Li Z,Zhao C,Sun Z,Shen Y,Leng Q,Zhou D,Han Z,Huang H,Ren H,Xu G,Feng X
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Dec 13 00:00:00 EST 2018
REV-ERBα Regulates TH17 Cell Development and Autoimmunity.
Cell reports
Amir M,Chaudhari S,Wang R,Campbell S,Mosure SA,Chopp LB,Lu Q,Shang J,Pelletier OB,He Y,Doebelin C,Cameron MD,Kojetin DJ,Kamenecka TM,Solt LA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Dec 26 00:00:00 EST 2018
CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis.
JCI insight
Beffinger M,Tallón de Lara P,Tugues S,Vermeer M,Montagnolo Y,Ohs I,Cecconi V,Lucchiari G,Gagliardi A,Misljencevic N,Sutton J,Spörri R,Becher B,Gupta A,van den Broek M
14-5773 was used in Flow cytometry/Cell sorting to reveal that neo-adjuvant treatment of mouse lung cancer with CSF1R blockade unexpectedly promoted metastasis and indirectly caused a reduction in the number of NK cells.
Thu May 17 00:00:00 EDT 2018
Multidrug-resistant Pseudomonas aeruginosa aggravates inflammatory responses in murine chronic colitis.
Scientific reports
von Klitzing E,Ekmekciu I,Kühl AA,Bereswill S,Heimesaat MM
14-5773 was used in Immunohistochemistry to study whether chronic murine gut inflammation facilitates intestinal multi-drug resistant Pseudomonas aeruginosa colonisation, and whether bacterial infection subsequently worsens colonic immunopathology.
Fri Apr 27 00:00:00 EDT 2018
Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate.
Scientific reports
Luu M,Weigand K,Wedi F,Breidenbend C,Leister H,Pautz S,Adhikary T,Visekruna A
14-5773 was used in Flow cytometry/Cell sorting to might have significant implications in adoptive immunotherapy of cancers and in anti-viral immunity.
Wed Sep 26 00:00:00 EDT 2018
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.
Cell
Overacre-Delgoffe AE,Chikina M,Dadey RE,Yano H,Brunazzi EA,Shayan G,Horne W,Moskovitz JM,Kolls JK,Sander C,Shuai Y,Normolle DP,Kirkwood JM,Ferris RL,Delgoffe GM,Bruno TC,Workman CJ,Vignali DAA
14-5773 was used in Flow cytometry/Cell sorting to identify the basis for Nrp1 dependency and the key drivers of Treg fragility to improve immunotherapy for human cancer.
Thu Jun 01 00:00:00 EDT 2017
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Cancer cell
Palazon A,Tyrakis PA,Macias D,Veliça P,Rundqvist H,Fitzpatrick S,Vojnovic N,Phan AT,Loman N,Hedenfalk I,Hatschek T,Lövrot J,Foukakis T,Goldrath AW,Bergh J,Johnson RS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Nov 13 00:00:00 EST 2017
Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.
Cancer discovery
Loo TM,Kamachi F,Watanabe Y,Yoshimoto S,Kanda H,Arai Y,Nakajima-Takagi Y,Iwama A,Koga T,Sugimoto Y,Ozawa T,Nakamura M,Kumagai M,Watashi K,Taketo MM,Aoki T,Narumiya S,Oshima M,Arita M,Hara E,Ohtani N
14-5773 was used in Flow cytometry/Cell sorting to show that the hepatic translocation of obesity-induced lipoteichoic acid (LTA), a Gram-positive gut microbial component, promotes HCC development by creating a tumor-promoting microenvironment.
Mon May 01 00:00:00 EDT 2017
Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.
Cell host & microbe
Scharschmidt TC,Vasquez KS,Pauli ML,Leitner EG,Chu K,Truong HA,Lowe MM,Sanchez Rodriguez R,Ali N,Laszik ZG,Sonnenburg JL,Millar SE,Rosenblum MD
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Apr 12 00:00:00 EDT 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program.
Nature immunology
Wu C,Chen Z,Dardalhon V,Xiao S,Thalhamer T,Liao M,Madi A,Franca RF,Han T,Oukka M,Kuchroo V
14-5773 was used in Flow cytometry/Cell sorting to identify the TF Musculin (MSC) as critical for iTreg development by repression of TH2 transcriptional program, using Transforming growth factor-β (TGF-β) induced regulatory T cell (iTreg) system.
Wed Mar 01 00:00:00 EST 2017
Different molecular complexes that mediate transcriptional induction and repression by FoxP3.
Nature immunology
Kwon HK,Chen HM,Mathis D,Benoist C
14-5773 was used in Western Blotting to show that FoxP3 acts in multimodal fashion to directly activate or repress transcription, in a context- and partner-dependent manner, to govern Tregcell phenotypes.
Wed Nov 01 00:00:00 EDT 2017
CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.
The Journal of clinical investigation
Doran AC,Ozcan L,Cai B,Zheng Z,Fredman G,Rymond CC,Dorweiler B,Sluimer JC,Hsieh J,Kuriakose G,Tall AR,Tabas I
14-5773-82 was used in Immunohistochemistry to identify a macrophage CaMKIIγ/ATF6/LXRα/MerTK pathway as a key factor in the development of necrotic atherosclerotic plaques.
Wed Nov 01 00:00:00 EDT 2017
Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment.
The Journal of clinical investigation
Wang YT,Chen J,Chang CW,Jen J,Huang TY,Chen CM,Shen R,Liang SY,Cheng IC,Yang SC,Lai WW,Cheng KH,Hsieh TS,Lai MZ,Cheng HC,Wang YC,Chen RH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling.
The Journal of clinical investigation
Ansa-Addo EA,Zhang Y,Yang Y,Hussey GS,Howley BV,Salem M,Riesenberg B,Sun S,Rockey DC,Karvar S,Howe PH,Liu B,Li Z
14-5773 was used in Western Blotting to investigate whether moesin plays a role during the generation of TGF-β-induced Tregs, showing that it controls Treg differentiation and antitumor immunity.
Mon Apr 03 00:00:00 EDT 2017
Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling.
The Journal of clinical investigation
Ansa-Addo EA,Zhang Y,Yang Y,Hussey GS,Howley BV,Salem M,Riesenberg B,Sun S,Rockey DC,Karvar S,Howe PH,Liu B,Li Z
14-5773 was used in Western Blotting to investigate whether moesin plays a role during the generation of TGF-β-induced Tregs, showing that it controls Treg differentiation and antitumor immunity.
Mon Apr 03 00:00:00 EDT 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction.
The Journal of clinical investigation
Ramjee V,Li D,Manderfield LJ,Liu F,Engleka KA,Aghajanian H,Rodell CB,Lu W,Ho V,Wang T,Li L,Singh A,Cibi DM,Burdick JA,Singh MK,Jain R,Epstein JA
14-5773 was used in Immunocytochemistry-immunoflourescence to suggest that epicardial Hippo signalling plays a key role in adaptive immune regulation during the post-myocardial infarction recovery phase.
Wed Mar 01 00:00:00 EST 2017
Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction.
The Journal of clinical investigation
Ramjee V,Li D,Manderfield LJ,Liu F,Engleka KA,Aghajanian H,Rodell CB,Lu W,Ho V,Wang T,Li L,Singh A,Cibi DM,Burdick JA,Singh MK,Jain R,Epstein JA
14-5773 was used in Immunocytochemistry-immunoflourescence to suggest that epicardial Hippo signalling plays a key role in adaptive immune regulation during the post-myocardial infarction recovery phase.
Wed Mar 01 00:00:00 EST 2017
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
The Journal of clinical investigation
Chung J,Ebens CL,Perkey E,Radojcic V,Koch U,Scarpellino L,Tong A,Allen F,Wood S,Feng J,Friedman A,Granadier D,Tran IT,Chai Q,Onder L,Yan M,Reddy P,Blazar BR,Huang AY,Brennan TV,Bishop DK,Ludewig B,Siebel CW,Radtke F,Luther SA,Maillard I
14-5773 was used in Flow cytometry/Cell sorting to reveal what we believe to be a previously unrecognised Notch-mediated immunopathogenic role for stromal cell niches in secondary lymphoid organs after allo-BMT and define a framework of early cellular and molecular interactions that regulate T cell alloimmunity.
Mon Apr 03 00:00:00 EDT 2017
PTEN drives Th17 cell differentiation by preventing IL-2 production.
The Journal of experimental medicine
Kim HS,Jang SW,Lee W,Kim K,Sohn H,Hwang SS,Lee GR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Nov 06 00:00:00 EST 2017
LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Xu X,Han L,Zhao G,Xue S,Gao Y,Xiao J,Zhang S,Chen P,Wu ZY,Ding J,Hu R,Wei B,Wang H
14-5773 was used in Flow cytometry/Cell sorting to demonstrate LRCH1 as a novel effector to restrain PKCα-DOCK8-Cdc42 module-induced T cell migration and ameliorate EAE.
Sun Jan 01 00:00:00 EST 2017
NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
The Journal of experimental medicine
Daley D,Mani VR,Mohan N,Akkad N,Pandian GSDB,Savadkar S,Lee KB,Torres-Hernandez A,Aykut B,Diskin B,Wang W,Farooq MS,Mahmud AI,Werba G,Morales EJ,Lall S,Wadowski BJ,Rubin AG,Berman ME,Narayanan R,Hundeyin M,Miller G
14-5773-82 was used in Flow Cytometry to suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.
Mon Jun 05 00:00:00 EDT 2017
NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
The Journal of experimental medicine
Daley D,Mani VR,Mohan N,Akkad N,Pandian GSDB,Savadkar S,Lee KB,Torres-Hernandez A,Aykut B,Diskin B,Wang W,Farooq MS,Mahmud AI,Werba G,Morales EJ,Lall S,Wadowski BJ,Rubin AG,Berman ME,Narayanan R,Hundeyin M,Miller G
14-5773-82 was used in Flow Cytometry to suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.
Mon Jun 05 00:00:00 EDT 2017
Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI.
Journal of the American Society of Nephrology : JASN
Martin-Sanchez D,Ruiz-Andres O,Poveda J,Carrasco S,Cannata-Ortiz P,Sanchez-Niño MD,Ruiz Ortega M,Egido J,Linkermann A,Ortiz A,Sanz AB
14-5773 was used in Immunohistochemistry to suggest that ferroptosis is the primary cause of FA-AKI and that immunogenicity secondary to ferroptosis may worsen the damage.
Sun Jan 01 00:00:00 EST 2017
Administration of RANKL boosts thymic regeneration upon bone marrow transplantation.
EMBO molecular medicine
Lopes N,Vachon H,Marie J,Irla M
14-5773 was used in Flow cytometry/Cell sorting to indicate that RANKL may be clinically useful to improve T-cell function recovery after bone marrow transplantation by controlling multiple facets of thymic regeneration.
Thu Jun 01 00:00:00 EDT 2017
Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen.
Cancer research
Probst P,Kopp J,Oxenius A,Colombo MP,Ritz D,Fugmann T,Neri D
14-5773 was used in Immunohistochemistry-immunofluorescence to study the use of TNF-linked antibodies to eradicate sarcomas in immunocompetent mice.
Sat Jul 01 00:00:00 EDT 2017
Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion.
Proceedings of the National Academy of Sciences of the United States of America
Miosge LA,Sontani Y,Chuah A,Horikawa K,Russell TA,Mei Y,Wagle MV,Howard DR,Enders A,Tscharke DC,Goodnow CC,Parish IA
14-5773 was used in Flow cytometry/Cell sorting to identify a crucial role for ETAA1 in this process by surveying random germ line mutations in mice using exome sequencing and bioinformatic annotation to prioritise mutations in genes of unknown function with potential effects on the immune system.
Tue Jun 27 00:00:00 EDT 2017
TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America
Lukas D,Yogev N,Kel JM,Regen T,Mufazalov IA,Tang Y,Wanke F,Reizis B,Müller W,Kurschus FC,Prinz M,Kleiter I,Clausen BE,Waisman A
14-5773 was used in Flow cytometry/Cell sorting to demonstrate the role of Smad7 in the differentiation of dendritic cells in mice and their influence on the efficient function in immunity.
Tue Feb 21 00:00:00 EST 2017
IL-2 prevents deletion of developing T-regulatory cells in the thymus.
Cell death and differentiation
Hu DY,Wirasinha RC,Goodnow CC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
A bidirectional association between the gut microbiota and CNS disease in a biphasic murine model of multiple sclerosis.
Gut microbes
Colpitts SL,Kasper EJ,Keever A,Liljenberg C,Kirby T,Magori K,Kasper LH,Ochoa-Repáraz J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Nov 02 00:00:00 EDT 2017
RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells.
Frontiers in immunology
Döhler A,Schneider T,Eckert I,Ribechini E,Andreas N,Riemann M,Reizis B,Weih F,Lutz MB
14-5773 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying how dendritic cells manage to keep the peripheral pool of natural Foxp3+ regulatory T cells at constant levels.
Wed Nov 20 00:00:00 EST 2019
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.
The Journal of cell biology
Vander Lugt B,Riddell J,Khan AA,Hackney JA,Lesch J,DeVoss J,Weirauch MT,Singh H,Mellman I
14-5773 was used in Flow cytometry/Cell sorting to study how DCs modulate their ability to prime tolerogenic or immunogenic T cells by expressing a core antigen presentation module that is overlaid by distinctive regulatory modules to promote either tolerance or immunity.
Mon Mar 06 00:00:00 EST 2017
Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy.
International journal of cancer
Santos JM,Havunen R,Siurala M,Cervera-Carrascon V,Tähtinen S,Sorsa S,Anttila M,Karell P,Kanerva A,Hemminki A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Potency-matched Dual Cytokine-Antibody Fusion Proteins for Cancer Therapy.
Molecular cancer therapeutics
De Luca R,Soltermann A,Pretto F,Pemberton-Ross C,Pellegrini G,Wulhfard S,Neri D
14-5773 was used in Immunofluorescence in immunohistochemistry on frozen tissues to develop a novel biopharmaceutical, consisting of the F8 mAb (specific to a splice isoform of fibronectin) simultaneously fused to both TNF and IL2, for cancer therapy.
Wed Nov 01 00:00:00 EDT 2017
The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity.
The American journal of pathology
Yau ACY,Tuncel J,Holmdahl R
14-5773 was used in Flow cytometry/Cell sorting to find that Ltab-Ncr3 is specific in regulating adjuvant-induced arthritis but not antigen-induced autoimmunity.
Mon May 01 00:00:00 EDT 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.
Journal of immunology (Baltimore, Md. : 1950)
Leigh ND,O'Neill RE,Du W,Chen C,Qiu J,Ashwell JD,McCarthy PL,Chen GL,Cao X
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that host CD70 serves as a unique negative regulator of allogeneic T cell response by contributing to donor T cell apoptosis and inhibiting expansion of donor effector T cells.
Sat Jul 01 00:00:00 EDT 2017
Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Kyburz A,Urban S,Altobelli A,Floess S,Huehn J,Cover TL,Müller A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis.
World journal of gastroenterology
Bartczak A,Zhang J,Adeyi O,Amir A,Grant D,Gorczynski R,Selzner N,Chruscinski A,Levy GA
Fri Apr 21 00:00:00 EDT 2017
Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Tear Production in a Mouse Model of Sjögren's Syndrome.
Stem cells international
Aluri HS,Samizadeh M,Edman MC,Hawley DR,Armaos HL,Janga SR,Meng Z,Sendra VG,Hamrah P,Kublin CL,Hamm-Alvarez SF,Zoukhri D
14-5773 was used in Immunohistochemistry to study the potential of mouse bone marrow-derived mesenchymal stem cells in improving tear production in Sjogren's syndorme and determine the underlying mechanisms.
Tue Aug 01 00:00:00 EDT 2023
Dichloroacetate induces regulatory T-cell differentiation and suppresses Th17-cell differentiation by pyruvate dehydrogenase kinase-independent mechanism.
The Journal of pharmacy and pharmacology
Makita N,Ishiguro J,Suzuki K,Nara F
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
miR-451 limits CD4+ T cell proliferative responses to infection in mice.
Immunologic research
Chapman LM,Ture SK,Field DJ,Morrell CN
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that miR-451 is a regulator of host immune responses to Plasmodium infection, particularly in the control of CD4+ T cell proliferation via a Myc-dependent pathway.
Tue Aug 01 00:00:00 EDT 2017
UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model.
Pigment cell & melanoma research
Wang J,Perry CJ,Meeth K,Thakral D,Damsky W,Micevic G,Kaech S,Blenman K,Bosenberg M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Jul 01 00:00:00 EDT 2017
UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model.
Pigment cell & melanoma research
Wang J,Perry CJ,Meeth K,Thakral D,Damsky W,Micevic G,Kaech S,Blenman K,Bosenberg M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Jul 01 00:00:00 EDT 2017
SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance.
Molecular pharmacology
Li J,Jing J,Bai Y,Li Z,Xing R,Tan B,Ma X,Qiu WW,Du C,Du B,Yang F,Tang J,Siwko S,Liu M,Chen H,Luo J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance.
Molecular medicine reports
Li Y,Li H,Cao Y,Wu F,Ma W,Wang Y,Sun S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions.
Cancer prevention research (Philadelphia, Pa.)
Wang J,Xie T,Wang B,William WN,Heymach JV,El-Naggar AK,Myers JN,Caulin C
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Dec 01 00:00:00 EST 2017
B cells inhibit the antitumor immunity against an established murine fibrosarcoma.
Oncology letters
Maglioco A,Machuca DG,Badano MN,Nannini P,Camerano GV,Costa H,Meiss R,Ruggiero RA,Giordano M,Dran GI
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs.
Oncology letters
Son CH,Bae J,Lee HR,Yang K,Park YS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model.
Oncology letters
Chen J,Zhang M,Zhou F,Wang J,Niu B,Zhang W
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Treatment with Allogenic Mesenchymal Stromal Cells in a Murine Model of Systemic Lupus Erythematosus.
International journal of stem cells
Tani C,Vagnani S,Carli L,Querci F,Kühl AA,Spieckermann S,Cieluch CP,Pacini S,Fazzi R,Mosca M
14-5773 was used in Immunohistochemistry on paraffin embedded tissues to study whether repeated administrations of 1x106/kg body weight of allogenic mesenchymal stromal cells can be effective in improving the clinical course of a murine systemic lupus erythematosus model.
Thu Nov 30 00:00:00 EST 2017
Proteomic changes of CD4+/CD25+/forkhead box p3+ regulatory T cells in a 30-day rat model of sepsis survival.
Experimental and therapeutic medicine
Jiao Y,Tan S,Xiong J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis.
PloS one
Bäcker V,Cheung FY,Siveke JT,Fandrey J,Winning S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jan 08 00:00:00 EST 2018
Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis.
PloS one
Bäcker V,Cheung FY,Siveke JT,Fandrey J,Winning S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jan 08 00:00:00 EST 2018
Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression.
Nature communications
Lu J,Liu X,Liao YP,Salazar F,Sun B,Jiang W,Chang CH,Jiang J,Wang X,Wu AM,Meng H,Nel AE
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Nov 27 00:00:00 EST 2017
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease.
Scientific reports
Minter MR,Hinterleitner R,Meisel M,Zhang C,Leone V,Zhang X,Oyler-Castrillo P,Zhang X,Musch MW,Shen X,Jabri B,Chang EB,Tanzi RE,Sisodia SS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Sep 05 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.
Nature communications
Kim KD,Bae S,Capece T,Nedelkovska H,de Rubio RG,Smrcka AV,Jun CD,Jung W,Park B,Kim TI,Kim M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2017
Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.
Oncotarget
Vachharajani N,Joeris T,Luu M,Hartmann S,Pautz S,Jenike E,Pantazis G,Prinz I,Hofer MJ,Steinhoff U,Visekruna A
14-5773 was used in Flow cytometry/Cell sorting to show selective targeting of the proteasomal immunosubunit LMP7 could be used as a preventative treatment for colitis-associated cancer.
Tue Aug 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.
Nature communications
Johnston CJC,Smyth DJ,Kodali RB,White MPJ,Harcus Y,Filbey KJ,Hewitson JP,Hinck CS,Ivens A,Kemter AM,Kildemoes AO,Le Bihan T,Soares DC,Anderton SM,Brenn T,Wigmore SJ,Woodcock HV,Chambers RC,Hinck AP,McSorley HJ,Maizels RM
14-5773-82 was used in Flow Cytometry to indicate that through the helminth parasite has acquired a protein with cytokine-like function that is able to exploit an endogenous pathway of immunoregulation in the host.
Thu Nov 23 00:00:00 EST 2017
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Nature communications
Mbofung RM,McKenzie JA,Malu S,Zhang M,Peng W,Liu C,Kuiatse I,Tieu T,Williams L,Devi S,Ashkin E,Xu C,Huang L,Zhang M,Talukder AH,Tripathi SC,Khong H,Satani N,Muller FL,Roszik J,Heffernan T,Allison JP,Lizee G,Hanash SM,Proia D,Amaria R,Davis RE,Hwu P
14-5773 was used in Flow cytometry to show HSP90 inhibitors can potentiate T-cell-mediated anti-tumor immune responses to enhance T-cell-mediated killing of melanoma cells.
Wed Sep 06 00:00:00 EDT 2017
Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model.
Oncoimmunology
Field CS,Hunn MK,Ferguson PM,Ruedl C,Ancelet LR,Hermans IF
14-5773 was used in Flow cytometry/Cell sorting to study the effect of the checkpoint blockade on the efficacy of responses induced with a whole tumour-cell vaccine.
Tue Jan 12 00:00:00 EST 2021
Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.
Nature communications
Liu Z,Ravindranathan R,Kalinski P,Guo ZS,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2017
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.
Stem cell reports
Shigemoto-Kuroda T,Oh JY,Kim DK,Jeong HJ,Park SY,Lee HJ,Park JW,Kim TW,An SY,Prockop DJ,Lee RH
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model.
BMC complementary and alternative medicine
Xie L,Zhong X,Liu D,Liu L,Xia Z
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Oncoimmunology
Huang RY,Francois A,McGray AR,Miliotto A,Odunsi K
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.
Nature communications
Kojo S,Tanaka H,Endo TA,Muroi S,Liu Y,Seo W,Tenno M,Kakugawa K,Naoe Y,Nair K,Moro K,Katsuragi Y,Kanai A,Inaba T,Egawa T,Venkatesh B,Minoda A,Kominami R,Taniuchi I
14-5773 was used in Flow cytometry/Cell sorting to show that a pre-commitment event modulated by the transcription factor, Bcl11b, is required for the proper expression of ThPOK and Runx3 and correct CD4/CD8 lineage commitment.
Tue Sep 26 00:00:00 EDT 2017
Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
PloS one
Komegae EN,Souza TA,Grund LZ,Lima C,Lopes-Ferreira M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.
The Journal of biological chemistry
Hayakawa M,Hayakawa H,Petrova T,Ritprajak P,Sutavani RV,Jiménez-Andrade GY,Sano Y,Choo MK,Seavitt J,Venigalla RKC,Otsu K,Georgopoulos K,Arthur JSC,Park JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2017
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.
The Journal of biological chemistry
Hayakawa M,Hayakawa H,Petrova T,Ritprajak P,Sutavani RV,Jiménez-Andrade GY,Sano Y,Choo MK,Seavitt J,Venigalla RKC,Otsu K,Georgopoulos K,Arthur JSC,Park JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2017
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.
The Journal of biological chemistry
Hayakawa M,Hayakawa H,Petrova T,Ritprajak P,Sutavani RV,Jiménez-Andrade GY,Sano Y,Choo MK,Seavitt J,Venigalla RKC,Otsu K,Georgopoulos K,Arthur JSC,Park JM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Lactobacillus johnsonii ameliorates intestinal, extra-intestinal and systemic pro-inflammatory immune responses following murine Campylobacter jejuni infection.
Scientific reports
Bereswill S,Ekmekciu I,Escher U,Fiebiger U,Stingl K,Heimesaat MM
14-5773 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to demonstrate that immunomodulatory probiotic species might offer valuable strategies for prophylaxis and/or treatment of C. jejuni induced intestinal, extra-intestinal and systemic pro-inflammatory immune responses in vivo.
Thu May 18 00:00:00 EDT 2017
Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells.
Oncotarget
Luu M,Jenike E,Vachharajani N,Visekruna A
14-5773 was used in Immunohistochemistry on paraffin embedded tissues to study the requirement of c-Rel in the generation of thymic regulatory T cells.
Tue Aug 08 00:00:00 EDT 2017
Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor.
eLife
Redhu NS,Bakthavatchalu V,Conaway EA,Shouval DS,Tsou A,Goettel JA,Biswas A,Wang C,Field M,Muller W,Bleich A,Li N,Gerber GK,Bry L,Fox JG,Snapper SB,Horwitz BH
14-5773 was used in Flow cytometry/Cell sorting to show that IL10R-mediated regulation of macrophage function during the early postnatal period is essential to prevent murine colitis.
Wed Jul 05 00:00:00 EDT 2017
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Nature medicine
Moynihan KD,Opel CF,Szeto GL,Tzeng A,Zhu EF,Engreitz JM,Williams RT,Rakhra K,Zhang MH,Rothschilds AM,Kumari S,Kelly RL,Kwan BH,Abraham W,Hu K,Mehta NK,Kauke MJ,Suh H,Cochran JR,Lauffenburger DA,Wittrup KD,Irvine DJ
14-5773 was used in Flow cytometry/Cell sorting to develop combined immunotherapy against established tumours.
Thu Dec 01 00:00:00 EST 2016
An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells.
Nature medicine
Massoud AH,Charbonnier LM,Lopez D,Pellegrini M,Phipatanakul W,Chatila TA
14-5773 was used in Flow cytometry/Cell sorting to identify a previously unknown mechanism for the development of TH17 cell inflammation in genetically prone individuals.
Thu Sep 01 00:00:00 EDT 2016
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Nature genetics
Jabara HH,Boyden SE,Chou J,Ramesh N,Massaad MJ,Benson H,Bainter W,Fraulino D,Rahimov F,Sieff C,Liu ZJ,Alshemmari SH,Al-Ramadi BK,Al-Dhekri H,Arnaout R,Abu-Shukair M,Vatsayan A,Silver E,Ahuja S,Davies EG,Sola-Visner M,Ohsumi TK,Andrews NC,Notarangelo LD,Fleming MD,Al-Herz W,Kunkel LM,Geha RS
14-5773 was used in Flow cytometry/Cell sorting to demonstrate the importance of TfR1 in adaptive immunity.
Fri Jan 01 00:00:00 EST 2016
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance.
Cancer cell
Pietrocola F,Pol J,Vacchelli E,Rao S,Enot DP,Baracco EE,Levesque S,Castoldi F,Jacquelot N,Yamazaki T,Senovilla L,Marino G,Aranda F,Durand S,Sica V,Chery A,Lachkar S,Sigl V,Bloy N,Buque A,Falzoni S,Ryffel B,Apetoh L,Di Virgilio F,Madeo F,Maiuri MC,Zitvogel L,Levine B,Penninger JM,Kroemer G
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Jul 11 00:00:00 EDT 2016
Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.
Nature immunology
Xing S,Li F,Zeng Z,Zhao Y,Yu S,Shan Q,Li Y,Phillips FC,Maina PK,Qi HH,Liu C,Zhu J,Pope RM,Musselman CA,Zeng C,Peng W,Xue HH
14-5773 was used in Flow cytometry/Cell sorting to reveal that sequence-specific transcription factors can utilise intrinsic HDAC activity to guard cell identity by repressing lineage-inappropriate genes.
Wed Jun 01 00:00:00 EDT 2016
FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy.
The Journal of clinical investigation
Lexmond WS,Goettel JA,Lyons JJ,Jacobse J,Deken MM,Lawrence MG,DiMaggio TH,Kotlarz D,Garabedian E,Sackstein P,Nelson CC,Jones N,Stone KD,Candotti F,Rings EH,Thrasher AJ,Milner JD,Snapper SB,Fiebiger E
14-5773 was used in Flow cytometry/Cell sorting to investigate the mechanism by which FOXP3+ T regulatory cells and WASP protein together restrain Th-2 mediated food allergy.
Mon Oct 03 00:00:00 EDT 2016
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
The Journal of clinical investigation
Massaad MJ,Zhou J,Tsuchimoto D,Chou J,Jabara H,Janssen E,Glauzy S,Olson BG,Morbach H,Ohsumi TK,Schmitz K,Kyriacos M,Kane J,Torisu K,Nakabeppu Y,Notarangelo LD,Chouery E,Megarbane A,Kang PB,Al-Idrissi E,Aldhekri H,Meffre E,Mizui M,Tsokos GC,Manis JP,Al-Herz W,Wallace SS,Geha RS
14-5773 was used in Flow cytometry/Cell sorting to investigate alterations in immune cell apoptosis during autoimmunity, showing that deficiency in NEIL3 drives increased predisposition to autoimmunity.
Tue Nov 01 00:00:00 EDT 2016
Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.
The Journal of experimental medicine
Everts B,Tussiwand R,Dreesen L,Fairfax KC,Huang SC,Smith AM,O'Neill CM,Lam WY,Edelson BT,Urban JF,Murphy KM,Pearce EJ
14-5773 was used in Flow cytometry/Cell sorting to investigate the role of CD8α+ and CD103+ dendritic cells in suppressing helminth-driven type 2 immune responses.
Mon Jan 11 00:00:00 EST 2016
Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.
The Journal of experimental medicine
Liu H,Jain R,Guan J,Vuong V,Ishido S,La Gruta NL,Gray DH,Villadangos JA,Mintern JD
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that the ligase MARCH 8 is responsible for regulating surface MHC II in thymic epithelial cells (TECs).
Mon Aug 22 00:00:00 EDT 2016
pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation.
Journal of autoimmunity
Duraes FV,Lippens C,Steinbach K,Dubrot J,Brighouse D,Bendriss-Vermare N,Issazadeh-Navikas S,Merkler D,Hugues S
14-5773 was used in Flow cytometry/Cell sorting to investigate novel pDC-based cell therapies in autoimmune diseases, aiming at specifically modulating pathogenic cells that induce and sustain autoimmune inflammation.
Mon Feb 01 00:00:00 EST 2016
A novel splenic B1 regulatory cell subset suppresses allergic disease through phosphatidylinositol 3-kinase-Akt pathway activation.
The Journal of allergy and clinical immunology
Matsushita T,Le Huu D,Kobayashi T,Hamaguchi Y,Hasegawa M,Naka K,Hirao A,Muramatsu M,Takehara K,Fujimoto M
14-5773 was used in Immunohistochemistry to investigate the signaling mechanisms and a novel phenotypic parameter of B10 cells in mice.
Sat Oct 01 00:00:00 EDT 2016
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis.
Autophagy
Lee HY,Kim J,Quan W,Lee JC,Kim MS,Kim SH,Bae JW,Hur KY,Lee MS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.
Cancer research
Lastwika KJ,Wilson W,Li QK,Norris J,Xu H,Ghazarian SR,Kitagawa H,Kawabata S,Taube JM,Yao S,Liu LN,Gills JJ,Dennis PA
14-5773 was used in Immunohistochemistry to suggest that oncogenic activation of the AKT-mTOR pathway promotes immune escape by driving expression of PD-L1.
Fri Jan 15 00:00:00 EST 2016
B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse.
European journal of immunology
Carrascal J,Carrillo J,Arpa B,Egia-Mendikute L,Rosell-Mases E,Pujol-Autonell I,Planas R,Mora C,Mauricio D,Ampudia RM,Vives-Pi M,Verdaguer J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.
Cancer immunology, immunotherapy : CII
Kroon P,Gadiot J,Peeters M,Gasparini A,Deken MA,Yagita H,Verheij M,Borst J,Blank CU,Verbrugge I
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed Jun 01 00:00:00 EDT 2016
Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.
Cancer immunology, immunotherapy : CII
Foy SP,Mandl SJ,dela Cruz T,Cote JJ,Gordon EJ,Trent E,Delcayre A,Breitmeyer J,Franzusoff A,Rountree RB
14-5773 was used in Flow cytometry/Cell sorting to help elucidate evidence of enhanced clinical benefit from combining CTLA-4 blockade with poxvirus-based active immunotherapy.
Sun May 01 00:00:00 EDT 2016
Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy.
Arthritis research & therapy
Bonnefoy F,Daoui A,Valmary-Degano S,Toussirot E,Saas P,Perruche S
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that apoptotic-cell-based therapy is efficient in treating ongoing CIA, compatible with current RA treatments, and needs to be evaluated in humans in the treatment of RA.
Thu Aug 11 00:00:00 EDT 2016
Multispectral Imaging of T and B Cells in Murine Spleen and Tumor.
Journal of immunology (Baltimore, Md. : 1950)
Feng Z,Jensen SM,Messenheimer DJ,Farhad M,Neuberger M,Bifulco CB,Fox BA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Sun May 01 00:00:00 EDT 2016
Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Jones LL,Alli R,Li B,Geiger TL
14-5773 was used in Flow cytometry/Cell sorting to demonstrate a key role for the regulation of receptor expression in differentiating the functional outcomes of IL-6 and IL-10 signalling.
Fri Apr 01 00:00:00 EDT 2016
IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod).
Journal of immunology (Baltimore, Md. : 1950)
Jirmo AC,Daluege K,Happle C,Albrecht M,Dittrich AM,Busse M,Habener A,Skuljec J,Hansen G
14-5773 was used in Flow cytometry/Cell sorting to study the mechanisms by which resiquimod mediates its therapeutic effects in experimental allergic asthma.
Thu Dec 01 00:00:00 EST 2016
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Journal of immunology (Baltimore, Md. : 1950)
Harakal J,Rival C,Qiao H,Tung KS
14-5773-82 was used in Flow Cytometry to suggest that Tregs maintain physiological tolerance to clinically relevant gastric autoantigens, and Th2 responses can be a pathogenic mechanism in AIG.
Fri Jul 01 00:00:00 EDT 2016
Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.
Journal of immunology (Baltimore, Md. : 1950)
Poczobutt JM,Nguyen TT,Hanson D,Li H,Sippel TR,Weiser-Evans MC,Gijon M,Murphy RC,Nemenoff RA
14-5773 was used in Flow cytometry/Cell sorting to reveal an antitumorigenic role for 5-LO products in the microenvironment during lung cancer progression through T cell regulation.
Fri Jan 15 00:00:00 EST 2016
A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Chen LC,Nicholson YT,Rosborough BR,Thomson AW,Raimondi G
14-5773 was used in Flow cytometry/Cell sorting to provide a framework for how the migratory behaviour of Treg and Tconv might be differentially regulated for therapeutic purposes.
Mon Aug 15 00:00:00 EDT 2016
Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3-/- Mice.
Mediators of inflammation
Hirota SA,Ueno A,Tulk SE,Becker HM,Schenck LP,Potentier MS,Li Y,Ghosh S,Muruve DA,MacDonald JA,Beck PL
14-5773 was used in Flow cytometry/Cell sorting to suggest that the NLRP3 inflammasome can regulate intestinal inflammation through noncanonical mechanisms.
Mon Jun 05 00:00:00 EDT 2017
Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity.
Genes and immunity
Bearoff F,Del Rio R,Case LK,Dragon JA,Nguyen-Vu T,Lin CY,Blankenhorn EP,Teuscher C,Krementsov DN
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model.
Molecular medicine reports
Yue Y,Li P,Song N,Li B,Li Z,Guo Y,Zhang W,Wei MQ,Gai Z,Meng H,Wang J,Qin L
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice.
Islets
Kumano K,Nishinakamura H,Mera T,Itoh T,Takahashi H,Fujiwara T,Kodama S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Sep 02 00:00:00 EDT 2016
Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice.
Islets
Kumano K,Nishinakamura H,Mera T,Itoh T,Takahashi H,Fujiwara T,Kodama S
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Fri Sep 02 00:00:00 EDT 2016
Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin.
Veterinary immunology and immunopathology
Wang Z,Navarro-Alvarez N,Shah JA,Zhang H,Huang Q,Zheng Q,Madsen JC,Sachs DH,Huang CA,Wang Z
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.
JCI insight
Federico G,Meister M,Mathow D,Heine GH,Moldenhauer G,Popovic ZV,Nordström V,Kopp-Schneider A,Hielscher T,Nelson PJ,Schaefer F,Porubsky S,Fliser D,Arnold B,Gröne HJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jan 21 00:00:00 EST 2016
Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.
JCI insight
Federico G,Meister M,Mathow D,Heine GH,Moldenhauer G,Popovic ZV,Nordström V,Kopp-Schneider A,Hielscher T,Nelson PJ,Schaefer F,Porubsky S,Fliser D,Arnold B,Gröne HJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Thu Jan 21 00:00:00 EST 2016
Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells.
PloS one
Hashimoto A,Sato T,Iyama S,Yoshida M,Ibata S,Tatekoshi A,Kamihara Y,Horiguchi H,Murase K,Kawano Y,Takada K,Miyanishi K,Kobune M,Ichimiya S,Kato J
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Mon Aug 08 00:00:00 EDT 2016
Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination.
Nature communications
Du C,Duan Y,Wei W,Cai Y,Chai H,Lv J,Du X,Zhu J,Xie X
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2016
Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis.
Stem cell research & therapy
Bravo B,Gallego MI,Flores AI,Bornstein R,Puente-Bedia A,Hernández J,de la Torre P,García-Zaragoza E,Perez-Tavarez R,Grande J,Ballester A,Ballester S
14-5773 was used in Flow cytometry/Cell sorting to explore the therapeutic potential of DMSCs for treatment of autoimmune disorders.
Thu Mar 17 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Nature communications
Göbel K,Pankratz S,Asaridou CM,Herrmann AM,Bittner S,Merker M,Ruck T,Glumm S,Langhauser F,Kraft P,Krug TF,Breuer J,Herold M,Gross CC,Beckmann D,Korb-Pap A,Schuhmann MK,Kuerten S,Mitroulis I,Ruppert C,Nolte MW,Panousis C,Klotz L,Kehrel B,Korn T,Langer HF,Pap T,Nieswandt B,Wiendl H,Chavakis T,Kleinschnitz C,Meuth SG
14-5773 was used in Flow cytometry/Cell sorting to study how immune activation by FXII is mediated by dendritic cells in a CD87-dependent manner, and involves alterations in intracellular cyclic AMP formation.
Wed May 18 00:00:00 EDT 2016
Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4+ recent thymic emigrants.
Scientific reports
Xu X,Jin R,Li M,Wang K,Zhang S,Hao J,Sun X,Zhang Y,Wu H,Zhang J,Ge Q
14-5773 was used in Flow cytometry/Cell sorting to investigate the tolerance of liver-persisting CD4(+) recent thymic emigrants.
Fri Jan 22 00:00:00 EST 2016
NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes.
Scientific reports
Zang C,Luyten A,Chen J,Liu XS,Shivdasani RA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Western Blot
Tue Jul 26 00:00:00 EDT 2016
Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor.
Scientific reports
Brandstätter O,Schanz O,Vorac J,König J,Mori T,Maruyama T,Korkowski M,Haarmann-Stemmann T,von Smolinski D,Schultze JL,Abel J,Esser C,Takeyama H,Weighardt H,Förster I
14-5773 was used in Flow cytometry/Cell sorting to highlight the physiologic importance of cell-type specific balancing of AhR/AhRR expression in response to microbial, nutritional and other environmental stimuli.
Tue May 17 00:00:00 EDT 2016
Vitamin D3 improves the effects of low dose Der p 2 allergoid treatment in Der p 2 sensitized BALB/c mice.
Clinical and molecular allergy : CMA
Petrarca C,Clemente E,Amato V,Gatta A,Cortese S,Lamolinara A,Rossi C,Zanotta S,Mistrello G,Paganelli R,Di Gioacchino M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Aug 08 00:00:00 EDT 2016
Vitamin D3 improves the effects of low dose Der p 2 allergoid treatment in Der p 2 sensitized BALB/c mice.
Clinical and molecular allergy : CMA
Petrarca C,Clemente E,Amato V,Gatta A,Cortese S,Lamolinara A,Rossi C,Zanotta S,Mistrello G,Paganelli R,Di Gioacchino M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Aug 08 00:00:00 EDT 2016
Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling.
Scientific reports
Pane JA,Fleming FE,Graham KL,Thomas HE,Kay TW,Coulson BS
14-5773 was used in Flow cytometry/Cell sorting to investigate the mechanisms of diabetes acceleration by rotaviruses.
Wed Jul 13 00:00:00 EDT 2016
Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition.
Oncoimmunology
Kleinpeter P,Fend L,Thioudellet C,Geist M,Sfrontato N,Koerper V,Fahrner C,Schmitt D,Gantzer M,Remy-Ziller C,Brandely R,Villeval D,Rittner K,Silvestre N,Erbs P,Zitvogel L,Quéméneur E,Préville X,Marchand JB
14-5773 was used in Flow cytometry/Cell sorting to develop a method to vectorise a hamster monoclonal IgG against murine PD-1 in Western Reserve oncolytic vaccina virus.
Tue Jan 12 00:00:00 EST 2021
Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice.
PloS one
Uhde AK,Herder V,Akram Khan M,Ciurkiewicz M,Schaudien D,Teich R,Floess S,Baumgärtner W,Huehn J,Beineke A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Aug 25 00:00:00 EDT 2017
Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice.
PloS one
Uhde AK,Herder V,Akram Khan M,Ciurkiewicz M,Schaudien D,Teich R,Floess S,Baumgärtner W,Huehn J,Beineke A
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Fri Aug 25 00:00:00 EDT 2017
Stat3 Is Important for Follicular Regulatory T Cell Differentiation.
PloS one
Wu H,Xie MM,Liu H,Dent AL
14-5773 was used in Flow cytometry/Cell sorting to uncover unique roles of Stat3 in Tfr cell differentiation and the regulation of the antibody response.
Mon Jul 10 00:00:00 EDT 2017
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
PloS one
Selby MJ,Engelhardt JJ,Johnston RJ,Lu LS,Han M,Thudium K,Yao D,Quigley M,Valle J,Wang C,Chen B,Cardarelli PM,Blanset D,Korman AJ
14-5773 was used in Flow cytometry/Cell sorting to exhibit a preclinical strategy for the identification and development of highly effective antitumour combination immunotherapies.
Fri Aug 25 00:00:00 EDT 2017
Conditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression.
Clinical & translational immunology
Li K,Baird M,Yang J,Jackson C,Ronchese F,Young S
14-5773 was used in Flow cytometry/Cell sorting to provide valuable data for further research into in vitro expansion of CD4(+) Th1-like cells, with potential applications to cancer treatment involving ACT.
Mon Aug 01 00:00:00 EDT 2016
Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization.
JCI insight
Pilat N,Mahr B,Unger L,Hock K,Schwarz C,Farkas AM,Baranyi U,Wrba F,Wekerle T
14-5773 was used in Flow cytometry/Cell sorting to suggest that deletion of donor-reactive T cells for specificities expressed on hematopoietic cells preclude the expansion of donor-specific Tregs.
Thu May 19 00:00:00 EDT 2016
CD301b+ dendritic cells suppress T follicular helper cells and antibody responses to protein antigens.
eLife
Kumamoto Y,Hirai T,Wong PW,Kaplan DH,Iwasaki A
14-5773 was used in Flow cytometry/Cell sorting to demonstrate a novel function of CD301b+ dendritic cells in negatively regulating antibody responses and preventing autoantibody formation.
Thu Sep 22 00:00:00 EDT 2016
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
Nature communications
Shi LZ,Fu T,Guan B,Chen J,Blando JM,Allison JP,Xiong L,Subudhi SK,Gao J,Sharma P
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Aug 08 00:00:00 EDT 2016
A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.
PloS one
Gossmann J,Stolte M,Lohoff M,Yu P,Moll R,Finkernagel F,Garn H,Brendel C,Bittner A,Neubauer A,Huynh MQ
14-5773 was used in Immunohistochemistry to demonstrate a correlation between a reduced immune response against H. felis, and protection from developing gastric mucosa-associated lymphoid tissue lymphomas.
Fri Nov 04 00:00:00 EDT 2016
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Immune homeostasis enforced by co-localized effector and regulatory T cells.
Nature
Liu Z,Gerner MY,Van Panhuys N,Levine AG,Rudensky AY,Germain RN
14-5773 was used in Immunofluorescence to reveal autoreactive T cells are activated to cytokine production, with co-clustering T cell receptor-stimulated Treg cells causing negative feedback, maintaining immune homeostasis.
Thu Dec 10 00:00:00 EST 2015
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology
Chen HJ,Sun J,Huang Z,Hou H,Arcilla M,Rakhilin N,Joe DJ,Choi J,Gadamsetty P,Milsom J,Nandakumar G,Longman R,Zhou XK,Edwards R,Chen J,Chen KY,Bu P,Wang L,Xu Y,Munroe R,Abratte C,Miller AD,Gümüş ZH,Shuler M,Nishimura N,Edelmann W,Shen X,Lipkin SM
14-5773 was used in Flow cytometry/Cell sorting to create chemokine-targeted mouse models that recapitulate the majority of common human somatic CRC mutations.
Mon Jun 01 00:00:00 EDT 2015
Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System.
Immunity
Guerrini MM,Okamoto K,Komatsu N,Sawa S,Danks L,Penninger JM,Nakashima T,Takayanagi H
14-5773-82 was used in Flow Cytometry to show that receptor activator of nuclear factor-κB (NF-κB) ligand (RANKL) on T cells regulates C-C type chemokine ligand 20 (CCL20) production by astrocytes and T cell localization in the CNS.
Tue Dec 15 00:00:00 EST 2015
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Nature immunology
Finkin S,Yuan D,Stein I,Taniguchi K,Weber A,Unger K,Browning JL,Goossens N,Nakagawa S,Gunasekaran G,Schwartz ME,Kobayashi M,Kumada H,Berger M,Pappo O,Rajewsky K,Hoshida Y,Karin M,Heikenwalder M,Ben-Neriah Y,Pikarsky E
14-5773 was used in Immunofluorescence-paraffin to reveal the function of ectopic lymphoid-like structures in cancer.
Tue Dec 01 00:00:00 EST 2015
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue.
Nature immunology
Lynch L,Michelet X,Zhang S,Brennan PJ,Moseman A,Lester C,Besra G,Vomhof-Dekrey EE,Tighe M,Koay HF,Godfrey DI,Leadbetter EA,Sant'Angelo DB,von Andrian U,Brenner MB
14-5773 was used in Flow cytometry/Cell sorting to report a unique transcriptional program of iNKT cells in adipose tissue, making them unique regulators of immunological homeostasis.
Thu Jan 01 00:00:00 EST 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Mon Mar 02 00:00:00 EST 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunofluorescence
Mon Mar 02 00:00:00 EST 2015
Podoplanin negatively regulates CD4+ effector T cell responses.
The Journal of clinical investigation
Peters A,Burkett PR,Sobel RA,Buckley CD,Watson SP,Bettelli E,Kuchroo VK
14-5773 was used in Flow cytometry/Cell sorting to investigate the effect of podoplanin on CD4+ effector T cell responses in mice.
Thu Jan 01 00:00:00 EST 2015
STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.
The Journal of clinical investigation
Desvignes L,Weidinger C,Shaw P,Vaeth M,Ribierre T,Liu M,Fergus T,Kozhaya L,McVoy L,Unutmaz D,Ernst JD,Feske S
14-5773 was used in Flow cytometry/Cell sorting to study the role of the activator stromal interaction molecule 1 (STIM1) on T cell regulation during chronic Mycobacterium tuberculosis infection.
Mon Jun 01 00:00:00 EDT 2015
Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis.
The Journal of clinical investigation
Nagy N,Kaber G,Johnson PY,Gebe JA,Preisinger A,Falk BA,Sunkari VG,Gooden MD,Vernon RB,Bogdani M,Kuipers HF,Day AJ,Campbell DJ,Wight TN,Bollyky PL
14-5773 was used in Immunohistochemistry to demonstrate that hyaluronan synthesis is critical for the pathogenesis of autoimmune diabetes.
Thu Oct 01 00:00:00 EDT 2015
Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease.
The Journal of clinical investigation
Bolton HA,Zhu E,Terry AM,Guy TV,Koh WP,Tan SY,Power CA,Bertolino P,Lahl K,Sparwasser T,Shklovskaya E,Fazekas de St Groth B
14-5773 was used in Flow cytometry/Cell sorting to indicate that achieving optimal recovery from lymphopenia should aim to improve early Treg reconstitution to increase the relative number of Tregs to DCs inhibiting spontaneous oligoclonal T cell proliferation.
Tue Sep 01 00:00:00 EDT 2015
Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers.
The Journal of experimental medicine
Rahimpour A,Koay HF,Enders A,Clanchy R,Eckle SB,Meehan B,Chen Z,Whittle B,Liu L,Fairlie DP,Goodnow CC,McCluskey J,Rossjohn J,Uldrich AP,Pellicci DG,Godfrey DI
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that mucosal-associated invariant T cells (MAIT cells) are detectable in a broad range of tissues in C57BL/6 and BALB/c mice.
Mon Jun 29 00:00:00 EDT 2015
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.
The Journal of allergy and clinical immunology
Roediger B,Kyle R,Tay SS,Mitchell AJ,Bolton HA,Guy TV,Tan SY,Forbes-Blom E,Tong PL,Köller Y,Shklovskaya E,Iwashima M,McCoy KD,Le Gros G,Fazekas de St Groth B,Weninger W
14-5773 was used in Immunohistochemistry to show that IL-2 signalling serves two distinct functions in lung group 2 innate lymphoid cells.
Tue Dec 01 00:00:00 EST 2015
Commensal microbiota influence systemic autoimmune responses.
The EMBO journal
Van Praet JT,Donovan E,Vanassche I,Drennan MB,Windels F,Dendooven A,Allais L,Cuvelier CA,van de Loo F,Norris PS,Kruglov AA,Nedospasov SA,Rabot S,Tito R,Raes J,Gaboriau-Routhiau V,Cerf-Bensussan N,Van de Wiele T,Eberl G,Ware CF,Elewaut D
14-5773 was used in Flow cytometry/Cell sorting to indicate that neonatal colonization of gut microbiota influences generalized autoimmunity in adult life.
Thu Feb 12 00:00:00 EST 2015
Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Dai M,Yip YY,Hellstrom I,Hellstrom KE
14-5773 was used in Flow cytometry/Cell sorting to assess immunologic and anti-tumour responses to the administration of various antibodies to various cancers.
Sun Mar 01 00:00:00 EST 2015
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells.
Cancer research
Hong Y,Manoharan I,Suryawanshi A,Majumdar T,Angus-Hill ML,Koni PA,Manicassamy B,Mellor AL,Munn DH,Manicassamy S
14-5773 was used in Flow cytometry/Cell sorting to show that dendritic cells in the tumour microenvironment acquire the ability to metabolise vitamin A to produce retinoic acid, driving immune tolerance.
Sun Feb 15 00:00:00 EST 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.
Hypertension (Dallas, Tex. : 1979)
Yodoi K,Yamashita T,Sasaki N,Kasahara K,Emoto T,Matsumoto T,Kita T,Sasaki Y,Mizoguchi T,Sparwasser T,Hirata K
14-5773 was used in Immunohistochemistry to suggest that Foxp3(+) Tregs may play a protective role in abdominal aortic aneurysm formation.
Wed Apr 01 00:00:00 EDT 2015
Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in Monkeys.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Yamada Y,Nadazdin O,Boskovic S,Lee S,Zorn E,Smith RN,Colvin RB,Madsen JC,Cosimi AB,Kawai T,Benichou G
14-5773-82 was used in immunohistochemistry (paraffin) to investigate the effect of repeated IL-2 injections on renal allograft tolerance in monkeys.
Tue Dec 01 00:00:00 EST 2015
Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway.
Mucosal immunology
Park J,Kim M,Kang SG,Jannasch AH,Cooper B,Patterson J,Kim CH
14-5773 was used in Flow cytometry/Cell sorting to show that short-chain fatty acids promote T-cell differentiation to promote either immunity or immune tolerance.
Thu Jan 01 00:00:00 EST 2015
Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.
Mucosal immunology
Bertin S,Lozano-Ruiz B,Bachiller V,García-Martínez I,Herdman S,Zapater P,Francés R,Such J,Lee J,Raz E,González-Navajas JM
14-5773 was used in Flow cytometry/Cell sorting to demonstrate that DUSP6 regulates CD4+ T-cell activation and differentiation by inhibiting TCR-dependent ERK1/2 activation.
Fri May 01 00:00:00 EDT 2015
Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection.
Mucosal immunology
Jiang TT,Chaturvedi V,Ertelt JM,Xin L,Clark DR,Kinder JM,Way SS
14-5773 was used in Flow cytometry/Cell sorting to study susceptibility against Candida albicans fungal infectiong following eradication of commensal enteric bacteria, showing loss of commensal bacteria enhances antifungal immunity through robust systemic expansion of Ly6G(hi)Ly6C(int) neutrophils, suggesting that enteric bacteria restrains activation of some immune components.
Wed Jul 01 00:00:00 EDT 2015
Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice.
PLoS pathogens
Mitagami Y,Yasunaga J,Kinosada H,Ohshima K,Matsuoka M
14-5773 was used in Flow cytometry/Cell sorting to investigate the effect of interferon-γ on inflammation and T-cell lymphoma development in HTLV-1 bZIP factor transgenic mice.
Sat Aug 01 00:00:00 EDT 2015
Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection.
PLoS pathogens
Hewitson JP,Filbey KJ,Esser-von Bieren J,Camberis M,Schwartz C,Murray J,Reynolds LA,Blair N,Robertson E,Harcus Y,Boon L,Huang SC,Yang L,Tu Y,Miller MJ,Voehringer D,Le Gros G,Harris N,Maizels RM
14-5773 was used in Flow cytometry/Cell sorting to show that vaccine-induced immunity to intestinal helminths involves both IgG1 antibodies and IL-25-dependent Type 2 myeloid effector populations.
Sun Mar 01 00:00:00 EST 2015
Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine.
Cancer science
Ohshio Y,Teramoto K,Hanaoka J,Tezuka N,Itoh Y,Asai T,Daigo Y,Ogasawara K
14-5773 was used in Immunohistochemistry on frozen tissues to study the immunosuppressive trait of CAFs, and systematically explore the alteration of tumour-associated immune responses by CAF-targeted therapy.
Sun Feb 01 00:00:00 EST 2015
Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis.
Molecular medicine (Cambridge, Mass.)
Li CH,Lin MH,Chu SH,Tu PH,Fang CC,Yen CH,Liang PI,Huang JC,Su YC,Sytwu HK,Chen YM
14-5773 was used in Immunocytochemistry to investigate whether glycine N-methyltransferase plays an immunomodulatory role in the pathogenesis of experimental autoimmune encephalomyelitis.
Tue Mar 24 00:00:00 EDT 2015
Down-regulation of survivin alleviates experimental arthritis.
Journal of leukocyte biology
Andersson KM,Svensson MN,Erlandsson MC,Jonsson IM,Bokarewa MI
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Thu Jan 01 00:00:00 EST 2015
Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models.
Molecular cancer therapeutics
Cuadrado-Castano S,Ayllon J,Mansour M,de la Iglesia-Vicente J,Jordan S,Tripathi S,García-Sastre A,Villar E
14-5773 was used in Flow cytometry/Cell sorting to demonstrate an augmented agent for cancer therapy which exploits the oncolytic properties of Newcastle disease virus.
Fri May 01 00:00:00 EDT 2015
Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors.
Molecular cancer therapeutics
Sato T,Shimosato T,Ueda A,Ishigatsubo Y,Klinman DM
14-5773 was used in Immunohistochemistry to examine the effect of instilling CpG oligonucleotides into the lungs of mice with non-small cell lung cancer.
Thu Oct 01 00:00:00 EDT 2015
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.
International journal of obesity (2005)
Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance.
Journal of immunology (Baltimore, Md. : 1950)
O'Hagan KL,Choi J,Pryshchep O,Chernoff J,Phee H
14-5773 was used in Flow cytometry/Cell sorting to show a novel role for the actin cytoskeletal remodeling protein, p21-activated kinase 2, in Treg development and homeostasis.
Sat Aug 15 00:00:00 EDT 2015
The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
Journal of immunology (Baltimore, Md. : 1950)
Presa M,Chen YG,Grier AE,Leiter EH,Brehm MA,Greiner DL,Shultz LD,Serreze DV
14-5773 was used in Flow cytometry/Cell sorting to indicate NSG recipients might be efficiently employed to test the activity of T1D patient-derived β cell-autoreactive T cell clones and lines.
Thu Oct 01 00:00:00 EDT 2015
IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production.
Journal of immunology (Baltimore, Md. : 1950)
Yokota S,Yoshida O,Dou L,Spadaro AV,Isse K,Ross MA,Stolz DB,Kimura S,Du Q,Demetris AJ,Thomson AW,Geller DA
14-5773 was used in Flow cytometry/Cell sorting to determine the role of IRF-1 during ischemia/reperfusion injury following allogeneic liver transplant, showing that it promotes injury via hepatocyte IL-15/IL-15Rα production.
Mon Jun 15 00:00:00 EDT 2015
Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Krishnamoorthy N,Burkett PR,Dalli J,Abdulnour RE,Colas R,Ramon S,Phipps RP,Petasis NA,Kuchroo VK,Serhan CN,Levy BD
14-5773 was used in Flow cytometry/Cell sorting to reveal that lung MaR1 augments de novo Treg generation, and that both Tregs and MaR1 inhibit ILC2s to restrain allergic lung inflammation.
Sun Feb 01 00:00:00 EST 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-5773-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 EDT 2015
Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.
Journal of immunology (Baltimore, Md. : 1950)
Suryawanshi A,Manoharan I,Hong Y,Swafford D,Majumdar T,Taketo MM,Manicassamy B,Koni PA,Thangaraju M,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-5773 was used in Flow cytometry/Cell sorting to study the factors in the tissue microenvironment and signalling networks critical for programming dendritic cells to control chronic inflammation and promote tolerance, showing that Th1/Th17 responses are regulated by canonical Wnt signalling in dendritic cells and suppresses autoimmune neuroinflammation.
Wed Apr 01 00:00:00 EDT 2015
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.
Journal of immunology (Baltimore, Md. : 1950)
Evonuk KS,Baker BJ,Doyle RE,Moseley CE,Sestero CM,Johnston BP,De Sarno P,Tang A,Gembitsky I,Hewett SJ,Weaver CT,Raman C,DeSilva TM
14-5773 was used in Flow cytometry/Cell sorting to investigate the link between inflammation and glutamate dysregulation in EAE, showing that inhibition of system Xc(-) transporter attenuates autoimmune inflammatory demyelination.
Wed Jul 15 00:00:00 EDT 2015
Regulatory T cells require TCR signaling for their suppressive function.
Journal of immunology (Baltimore, Md. : 1950)
Schmidt AM,Lu W,Sindhava VJ,Huang Y,Burkhardt JK,Yang E,Riese MJ,Maltzman JS,Jordan MS,Kambayashi T
14-5773 was used in Flow cytometry/Cell sorting to reveal that T cell receptor-mediated PLCγ activation is required for Tregs to inhibit Tconv proliferation.
Fri May 01 00:00:00 EDT 2015
PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Park HJ,Park JS,Jeong YH,Son J,Ban YH,Lee BH,Chen L,Chang J,Chung DH,Choi I,Ha SJ
14-5773 was used in Flow cytometry/Cell sorting to define PD-1 upregulated on Treg cells and its interaction with PD-1 ligand on effector T cells as one cause for the potent T cell suppression.
Mon Jun 15 00:00:00 EDT 2015
Leptin receptor signaling in T cells is required for Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Reis BS,Lee K,Fanok MH,Mascaraque C,Amoury M,Cohn LB,Rogoz A,Dallner OS,Moraes-Vieira PM,Domingos AI,Mucida D
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance.
Transplantation
Lal G,Nakayama Y,Sethi A,Singh AK,Burrell BE,Kulkarni N,Brinkman CC,Iwami D,Zhang T,Bromberg JS
14577382 was used in flow cytometry and immunohistochemistry to determine if specific B cell subsets or if B cell-derived interleukin-10 contributes to tolerance
Tue Sep 01 00:00:00 EDT 2015
Cytotoxic T lymphocyte-associated antigen 4 inhibition increases the antitumor activity of adoptive T-cell therapy when carried out with naïve rather than differentiated T cells.
Oncology reports
Ishikawa T,Adachi S,Okayama T,Kokura S,Mizushima K,Doi T,Matsuyama T,Sakamoto N,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Naito Y,Itoh Y,Yoshikawa T
14-5773 was used in Immunohistochemistry to explore the effect of combination therapy with cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibition and adoptive T-cell therapy in a clinical setting.
Fri May 01 00:00:00 EDT 2015
Introduction of Zinc-salt Fixation for Effective Detection of Immune Cell-related Markers by Immunohistochemistry.
Toxicologic pathology
Mori H,Soonsawad P,Schuetter L,Chen Q,Hubbard NE,Cardiff RD,Borowsky AD
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Sat Aug 01 00:00:00 EDT 2015
Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.
Journal for immunotherapy of cancer
Liao JB,Ovenell KJ,Curtis EE,Cecil DL,Koehnlein MR,Rastetter LR,Gad EA,Disis ML
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Immunohistochemistry
Wed May 20 00:00:00 EDT 2015
Injectable cryogel-based whole-cell cancer vaccines.
Nature communications
Bencherif SA,Warren Sands R,Ali OA,Li WA,Lewin SA,Braschler TM,Shih TY,Verbeke CS,Bhatta D,Dranoff G,Mooney DJ
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Wed Aug 12 00:00:00 EDT 2015
BTLA associates with increased Foxp3 expression in CD4(+) T cells in dextran sulfate sodium-induced colitis.
International journal of clinical and experimental pathology
Zhang HX,Zhu B,Fu XX,Zeng JC,Zhang JA,Wang WD,Kong B,Xiang WY,Zhong J,Wang CY,Zheng XB,Xu JF
14-5773 was used in Flow cytometry/Cell sorting to study the role of BLTA in ulcerative colitis, showing that the frequency Foxp3-expressing BLTA+CD4(+) T cells from the lamina propria was higher in mice with colitis, and treatment downregulated Foxp3 and IL-17 in BTLA+ cells.
Tue Mar 01 00:00:00 EST 2016
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.
Nature communications
Baruch K,Rosenzweig N,Kertser A,Deczkowska A,Sharif AM,Spinrad A,Tsitsou-Kampeli A,Sarel A,Cahalon L,Schwartz M
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2015
Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.
Neoplasia (New York, N.Y.)
Rios-Doria J,Durham N,Wetzel L,Rothstein R,Chesebrough J,Holoweckyj N,Zhao W,Leow CC,Hollingsworth R
14-5773 was used in Flow cytometry/Cell sorting to investigate the ability of doxorubicin and liposomal doxorubicin to enhance the antitumor response of different cancer immunotherapies in mouse models.
Sat Aug 01 00:00:00 EDT 2015
Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice.
PloS one
Kornete M,Mason ES,Girouard J,Lafferty EI,Qureshi S,Piccirillo CA
14-5773 was used in Flow cytometry/Cell sorting to reveal that CXCR3-mediated trafficking of Tregs could represent a mechanism of homeostatic immunoregulation during diabetogenesis.
Mon Apr 25 00:00:00 EDT 2016
Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance.
PloS one
Houlden A,Hayes KS,Bancroft AJ,Worthington JJ,Wang P,Grencis RK,Roberts IS
14-5773 was used in Flow cytometry/Cell sorting to investigate the effects of T. muris infection on the faecal microbiota of mice.
Wed Apr 06 00:00:00 EDT 2016
Matrix Metalloproteinase-2 Mediates Intestinal Immunopathogenesis in Campylobacter Jejuni-Infected Infant Mice.
European journal of microbiology & immunology
Alutis ME,Grundmann U,Hagen U,Fischer A,Kühl AA,Göbel UB,Bereswill S,Heimesaat MM
14-5773 was used in Immunohistochemistry to suggest an important role of MMP-2 in mediating Campylobacter jejuni-induced intestinal immunopathogenesis.
Tue Sep 01 00:00:00 EDT 2015
Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer.
Oncotarget
Patel MR,Jacobson BA,Ji Y,Drees J,Tang S,Xiong K,Wang H,Prigge JE,Dash AS,Kratzke AK,Mesev E,Etchison R,Federspiel MJ,Russell SJ,Kratzke RA
Published figure using FOXP3 monoclonal antibody (Product # 14-5773-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2015