This antibody recognizes native human FPRL1 protein expressed in transfected mammalian cells.
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALXR; FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl Peptide Receptor Like-1; Formyl peptide receptor-like 1; FPRH1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); LXA4 receptor; LXA4R; N-formyl peptide receptor 2; RFP
Gene Aliases: ALXR; FMLP-R-II; FMLPX; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090
Entrez Gene ID: (Human) 2358