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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant C-terminal fragment of human FXR2 (residues 414-658).|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||20 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||20 µg/ml|
|Western Blot (WB)||1:500-1:2500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: Hela whole cell extract, HeLa whole cell lysate.
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FMR1L2; fragile X mental retardation gene 2, autosomal homolog; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X mental retardation-related protein 2; fragile X-mental retardation 1-like 2
FMR1L2; FXR2; Fxr2h; FXR2P