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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from N-terminal extracellular domain of human FZD3 / Frizzled 3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||3 - 5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Frizzled 3; frizzled 3, seven transmembrane spanning receptor; Frizzled family receptor 3; Frizzled homolog 3; FZD3; HFz3; Wnt receptor frizzled-3