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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (SYPKQMPLSQV) corresponding to the C-terminus amino acids of FZD8|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
frizzled (Drosophila) homolog 8; frizzled 8; frizzled 8, seven transmembrane spanning receptor; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); Frizzled-8; FZ-8; FZD8; hFZ8; HGNC:4046
FZ-8; FZD8; hFZ8