|Radioimmune Assays (RIA)||5-10 µg/mL|
|Western Blot (WB)||5 ug/ml|
|Tested Species reactivity||Bovine|
|Host / Isotype||Mouse / IgG1|
|Immunogen||120kD activation peptide of bovine factor V.|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||50% water with 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-43006 detects Factor V in bovine samples.
MA1-43006 has successfully been used in RIA and Western blot applications.
MA1-43006 was derived from an epitope on the 120,000 activation peptide of bovine factor V.
Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activated protein C cofactor; Coagulation factor 5; Coagulation factor V; F5
Gene Aliases: F5
UniProt ID: (Bovine) Q28107
Entrez Gene ID: (Bovine) 280687
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter
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