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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Factor VII (CaFVII-22) purified from plasma.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17631 targets Factor VII 22 in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17631 immunogen is human Factor VII (CaFVII-22) purified from plasma.
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Coagulation factor 7; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; FVII coagulation protein; proconvertin; SPCA