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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Purified, native human Factor VIII A2 domain.|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27389 detects Factor VIII A2 domain from human samples.
MA1-27389 has been successfully used in Western blot procedures. This antibody binds both human factor VIII and human factor VIIIa in solid-phase ELISA. It binds human factor VIII A2 domain in immunoblotting techniques.
The MA1-27389 immunogen is purified, native human Factor VIII A2 domain.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
Haemophilia A is an X-linked, recessive, bleeding disorder caused by a deficiency in the activity of coagulation factor VIII. Affected individuals develop a variable phenotype of haemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disorder is caused by heterogeneous mutations in the factor VIII gene. Up to 30% of haemophilia A patients given therapeutic fVIII can make inhibitory antibodies, the majority of which are reactive with its C2 and A2 domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AHF; antihemophilic factor; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIIIc; DXS1253E; F8B; F8C; factor VIII F8B; FVIII; HEMA; RP11-115M6.7
AHF; DXS1253E; F8; F8B; F8C; FVIII; HEMA