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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:4,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1B5G3 |
Immunogen |
Fascin Fusion Protein Ag6074 (1-187 aa encoded by BC000521) |
Conjugate |
Unconjugated
|
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MTANGTAEA VQIQFGLINC GNKYLTAEAF GFKVNASASS LKKKQIWTLE QPPDEAGSAA VCLRSHLGRY LAADKDGNVT CEREVPGPDC RFLIVAHDDG RWSLQSEAHR RYFGGTEDRL SCFAQTVSPA EKWSVHIAMH PQVNIYSVTR KRYAHLSARP ADEIAVDRDV PWGVDSLITL AFQDQRYS (1-187 aa encoded by BC000521)
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; Fascin homolog 1; fascin homolog 1, actin-bundling protein; Fascin1; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein
Gene Aliases: FAN1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658
Entrez Gene ID: (Human) 6624
Molecular Function:
non-motor actin binding protein
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