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Staining of normal human peripheral blood cells with Anti-Human IgE PE and Mouse IgG2b K Isotype Control FITC (top) or Anti-Human Fc epsilon Receptor I alpha (FceR1) FITC (bottom, A18401). Cells in the lymphocyte gate were used for analysis (note: basophils reside in FSC/SSC position of lymphocytes).
|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b, kappa|
|Immunogen||alpha subunit of human Fc epsilon receptor I (FceR1)|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Fc epsilonR1 alpha is a subunit of the high affinity receptor of IgE to which it directly binds. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FcERI, RP11-550P17.3, FCE1A
Fc IgE receptor, alpha polypeptide, Fc epsilon RI alpha-chain, Fc-epsilon RI-alpha, high affinity immunoglobulin epsilon receptor alpha-subunit, high affinity immunoglobulin epsilon receptor subunit alpha, igE Fc receptor subunit alpha, immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide, High affinity immunoglobulin epsilon receptor subunit alpha, FcERI, FCER1A, FCE1A