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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||10 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||1-10ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25945 detects FGF basic from human samples.
MA1-25945 has been successfully used in immunohistochemistry (paraffin) and ELISA procedures.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
basic fibroblast growth factor bFGF; BFGF; FGFB; fibroblast growth factor 2 (basic); HBGF-2; heparin-binding growth factor 2; prostatropin
BFGF; FGF-2; FGF2; FGFB; HBGF-2