|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified full length native protein (Human).|
|Storage buffer||PBS, pH 7.2|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay-dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-21363 detects FGF Basic in Human samples.
MA1-21363 has been successfully used in ELISA and Western Blot procedures.
MA1-21363 immunogen corresponds to purified full length native protein (Human).
FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.