|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Sheep / IgG|
|Immunogen||Recombinant human basic FGF.|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18362 detects Basic FGF from human, mouse, and rat samples.
PA1-18362 has been successfully used in immunohistochemistry procedures.
The PA1-18362 immunogen is recombinant human basic FGF.
After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent.
Reconstitute with 100 ul of distilled water. Glycerol (1:1) may be added for additional stability.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.