|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat, Bovine, Human, Mouse, Not Applicable, Rhesus monkey|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant fibronectin protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||1:500-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-11981 targets Fibronectin in IF, WB and IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The MA5-11981 immunogen is recombinant fibronectin protein.
Fibronectin is a dimeric glycoprotein which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Characterization of chondrocyte sheets prepared using a co-culture method with temperature-responsive culture inserts.
MA5-11981 was used in immunohistochemistry - frozen section to characterize chondrocyte sheets culture prepared using synovial tissue co-culture
|Kokubo M,Sato M,Yamato M,Mitani G,Kutsuna T,Ebihara G,Okano T,Mochida J||Journal of tissue engineering and regenerative medicine (10:486)||2016|
|Not Applicable||Not Cited||
Effects of decellularized matrices derived from periodontal ligament stem cells and SHED on the adhesion, proliferation and osteogenic differentiation of human dental pulp stem cells in vitro.
MA5-11981 was used in immunocytochemistry to characterize the effects of decellularized matrices derived from SHED and periodontal ligament stem cells on proliferation, adhesion and osteogenic differentiation of human dental pulp stem cells in vitro
|Heng BC,Zhu S,Xu J,Yuan C,Gong T,Zhang C||Tissue and cell (48:133)||2016|
The immunohistochemical characterization of human fetal olfactory bulb and olfactory ensheathing cells in culture as a source for clinical CNS restoration.
MA5-11981 was used in immunocytochemistry to study human fetal olfactory bulb and olfactory ensheathing cells in culture as a source for clinical CNS restoration
|Liu K,Li Y,Wang H,Jiang X,Zhao Y,Sun D,Chen L,Young W,Huang H,Zhou C||Anatomical record (Hoboken, N.J. : 2007) (293:359)||2010|
|Rhesus monkey||20 ug/ml||
Progesterone withdrawal up-regulates fibronectin and integrins during menstruation and repair in the rhesus macaque endometrium.
MA5-11981 was used in immunocytochemistry to investigate the expression and cellular localization of fibronectin and fibronectin receptors during menstruation and repair in the primate endometrium
|Cao W,Mah K,Carroll RS,Slayden OD,Brenner RM||Human reproduction (Oxford, England) (22:3223)||2007|
|Rhesus monkey||Not Cited||
Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.
MA5-11981 was used in immunohistochemistry to study the ability of probiotic/prebiotic administration to improve gastrointestinal immune parameters in macaques infected with SIV
|Klatt NR,Canary LA,Sun X,Vinton CL,Funderburg NT,Morcock DR,Quiñones M,Deming CB,Perkins M,Hazuda DJ,Miller MD,Lederman MM,Segre JA,Lifson JD,Haddad EK,Estes JD,Brenchley JM||The Journal of clinical investigation (123:903)||2013|
RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy.
MA5-11981 was used in immunohistochemistry to investigate the importance of RhoB in thymocyte development
|Bravo-Nuevo A,O'Donnell R,Rosendahl A,Chung JH,Benjamin LE,Odaka C||International immunology (23:593)||2011|
Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin.
MA5-11981 was used in immunohistochemistry to develop an elastic 3-dimensional scaffold for fibroblst growth based in the use of symthetic human elastin
|Rnjak J,Li Z,Maitz PK,Wise SG,Weiss AS||Biomaterials (30:6469)||2009|
Molecular alteration of Ca(v)1.2 calcium channel in chronic myocardial infarction.
MA5-11981 was used in immunohistochemistry to study the role of Cav1.2 calcium channels in chronic myocardial infarction
|Liao P,Li G,Yu DJ,Yong TF,Wang JJ,Wang J,Soong TW||Pflugers Archiv : European journal of physiology (458:701)||2009|
The properties of bioengineered chondrocyte sheets for cartilage regeneration.
MA5-11981 was used in immunohistochemistry to evaluate a new cell-sheet technique for autologous chondrocyte implantation
|Mitani G,Sato M,Lee JI,Kaneshiro N,Ishihara M,Ota N,Kokubo M,Sakai H,Kikuchi T,Mochida J||BMC biotechnology (9:null)||2009|
A physical mechanism for coupling bone resorption and formation in adult human bone.
MA5-11981 was used in immunohistochemistry to investigate the molecular mechanism of bone remodeling with osteoclasts and osteoblasts
|Andersen TL,Sondergaard TE,Skorzynska KE,Dagnaes-Hansen F,Plesner TL,Hauge EM,Plesner T,Delaisse JM||The American journal of pathology (174:239)||2009|
Flow shear stress affects macromolecular accumulation through modulation of internal elastic lamina fenestrae.
MA5-11981 was used in immunohistochemistry to examine the role of flow shear stress in atherogenesis
|Guo ZY,Yan ZQ,Bai L,Zhang ML,Jiang ZL||Clinical biomechanics (Bristol, Avon) (23 Suppl 1:S104)||2008|
Uterine stretch regulates temporal and spatial expression of fibronectin protein and its alpha 5 integrin receptor in myometrium of unilaterally pregnant rats.
MA5-11981 was used in immunohistochemistry to study the role of uterine stretch in regulating the expression of fibronectin and its alpha 5 integrin receptor in pregnant rat myometrium
|Shynlova O,Williams SJ,Draper H,White BG,MacPhee DJ,Lye SJ||Biology of reproduction (77:880)||2007|
Melatonin protects against epirubicin-induced cardiotoxicity.
MA5-11981 was used in immunohistochemistry to study the role of melatonin in protecting against epirubicin-induced cardiotoxicity
|Guven A,Yavuz O,Cam M,Ercan F,Bukan N,Comunoglu C||Acta histochemica (109:52)||2007|
Expression of laminin and fibronectin in renal dysplasia.
MA5-11981 was used in immunohistochemistry to study the expression of laminin and fibronectin in renal dysplasia
|Menon S,Kakkar N,Radotra BD||Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society (7:568)||2005|
Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation.
MA5-11981 was used in immunohistochemistry to study the effect of the ACE inhibitor captopril on volume overload cardiomyopathy
|Plante E,Gaudreau M,Lachance D,Drolet MC,Roussel E,Gauthier C,Lapointe E,Arsenault M,Couet J||Canadian journal of physiology and pharmacology (82:191)||2004|
Mammary localization and abundance of laminin, fibronectin, and collagen IV proteins in prepubertal heifers.
MA5-11981 was used in immunohistochemistry and western blot to study the distribution of extracellular matrix proteins in mammary tissues in prepubertal heifers
|Berry SD,Howard RD,Akers RM||Journal of dairy science (86:2864)||2003|