|Tested species reactivity||Bovine, Dog, Horse, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (160 GDDGAFDKLRSWSRSIED 177) of Formin-like protein 3 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. It is suspected be involved in gastric cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.