|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 121 and 581 of Human Frizzled 10|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27174 targets Frizzled 10 in WB applications and shows reactivity with Human and mouse samples.
The PA5-27174 immunogen is synthetic peptide corresponding to a region within amino acids 121 and 581 of Human Frizzled 10.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.