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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from the N-terminal region of human and mouse Frizzled-2 (FZD2).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Expression profile of frizzled receptors in human medulloblastomas.
38-4700 was used in western blot to measure the expression of all ten members of the FZD gene family in medulloblastomas.
|Salsano E,Paterra R,Figus M,Menghi F,Maderna E,Pollo B,Solero CL,Massimi L,Finocchiaro G||Journal of neuro-oncology (106:271)||2012|
Dfrizzled2; Frizzled 2; frizzled 2, seven transmembrane spanning receptor; Frizzled family receptor 2; Frizzled homolog 2; Fz2; FZD2; HFz2; Mfz10; Rfz2
fz-2; Fz2; FZD2; fzE2; hFz2