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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||8 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%) Sheep, Rabbit (94%) Opossum (89%).
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Dfrizzled2; Frizzled 2; frizzled 2, seven transmembrane spanning receptor; Frizzled family receptor 2; Frizzled homolog 2; Fz2; FZD2; HFz2; Mfz10; Rfz2
fz-2; Fz2; FZD2; fzE2; hFz2