|Immunohistochemistry (Paraffin) (IHC (P))||8 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%) Sheep, Rabbit (94%) Opossum (89%).
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dfrizzled2; Frizzled 2; frizzled 2, seven transmembrane spanning receptor; Frizzled family receptor 2; Frizzled homolog 2; Frizzled-2; Fz-2; Fz2; FZD2; FzE2; HFz2; Mfz10; Rfz2
Gene Aliases: fz-2; Fz2; FZD2; fzE2; hFz2
UniProt ID: (Human) Q14332
Entrez Gene ID: (Human) 2535
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