|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues M(1) R G P G T A A S H S P C(12) of mouse Frizzled.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4137 detects mouse frizzled.
PA1-4137 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~40 kDa protein representing mouse fz in mouse pancreas lysate.
The PA1-4137 immunogen is a synthetic peptide corresponding to residues M(1) R G P G T A A S H S P C(12) of mouse Frizzled. This sequence is 91% conserved in rat.
A member of the frizzled (fz) family, which has been shown to be the transmembrane receptors for the Wnt molecules. Wnts have been implicated in embryonic induction, cell fate determination, control of cell polarity and malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.