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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (KLH conjugated) to the C-terminus.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
OPA1-15110 detects GPR105 from human samples.
OPA1-15110 has been successfully used in immunohistochemistry(frozen) procedures.
The OPA1-15110 immunogen is a synthetic peptide (KLH conjugated) corresponding to the C-terminus.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
GPR105 is a Sugar-Sensing Receptor. GPR105 is a G-protein -coupled receptor identifying a quiescent, primitive population of hematopoietic cells restricted to bone marrow. GPC105 has been suggested to mediates primitive cell responses to specific hematopoietic microenvironments and extends the known immune system functions of P2Y receptors to the stem cell level. GPR105 has also been suggested to play an important role in peripheral and neuroimmune function in response to extracellular UDP-sugars. GPR105 has been reported to be expressed in brain. ESTs have been isolated from kidney, placenta,uterus and heart/melanocyte/uterus libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
G protein coupled receptor for UDP-glucose; G protein-coupled receptor 105; G-protein coupled receptor 105; GPCR105; P2Y(14) receptor; P2Y14 receptor; purinergic receptor P2Y, G-protein coupled, 14; UDP-glucose receptor
BPR105; GPR105; KIAA0001; P2RY14; P2Y14