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|Tested species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Residues 42-54 [TRGAPRPPPSSPP] of GABAB2 protein|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30052 detects GPR51 from various samples.
PA1-30052 has been successfully used in Western blot applications.
The PA1-30052 immunogen is: Residues 42-54 [TRGAPRPPPSSPP] of GABAB2 protein
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FLJ36928; GABABR2; GPR51; GPRC3B; HRIHFB2099