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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-32707 detects GPCR SLC/MCH1 from human samples.
PA1-32707 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32707 immunogen is: Synthetic peptide, KLH conjugated.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
beta chemokine exodus-2; C-C motif chemokine 21; CKb9; Efficient Chemoattractant for Lymphocytes; MGC34555; SCYA21; secondary lymphoid tissue chemokine; SLC; small inducible cytokine subfamily A (Cys-Cys), member 21; TCA4
6Ckine; CKb9; ECL; RP11-195F19.22-001; SCYA21; SLC; TCA4
Signal transduction Cell surface receptor mediated signal transduction Cytokine and chemokine mediated signaling pathway Cell communication Ligand-mediated signaling Immunity and defense Cytokine/chemokine mediated immunity