|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-32846 detects GPCR TAS1R1 from human samples.
PA1-32846 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32846 immunogen is: Synthetic peptide, KLH conjugated.
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 70; G-protein coupled receptor 70; gm148; GPR70; seven transmembrane helix receptor; T1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR1
Gene Aliases: GM148; GPR70; T1R1; TAS1R1; TR1
UniProt ID: (Human) Q7RTX1
Entrez Gene ID: (Human) 80835
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